Abstract:An efficient continuous flow process for the macrolactonization of seco acids and diacids using diols in the presence of Mukaiyama reagent ( N -methyl-2-chloropyridinium iodide) has been developed for medium to large sized macrocyclic lactones. In comp...
Abstract:Herein, we have developed a new approach for the synthesis of 11 to 21-membered macrolactones via intramolecular dehydrogenative coupling of primary alcohols by using Ru-MACHO as a catalyst and Cs 2 CO 3 as a base. This protocol generated 11-21-ring-si...
Abstract:Herein we describe a new approach for end-to-end cyclization to construct macrocycles through the inter/intramolecular dehydrogenative coupling of alcohols and ketones in the presence of a Ru-MACHO catalyst. This method is highly atom economical and su...
Abstract:A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels. The results are obtained from a simultaneous fit to the reconstructed invaria...