Advanced Search Results For "Tomohisa Hattori"
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Ghrelin Enhancer, the Latest Evidence of Rikkunshito
Publication Type: Academic Journal
Source(s): Frontiers in Nutrition, Vol 8 (2021)
Abstract: Rikkunshito is a Japanese herbal medicine (Kampo) that has been attracting attention and researched by many researchers not only in Japan but also worldwide. There are 214 rikkunshito articles that can be searched on PubMed by August 2021. The reason w...
Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats
Publication Type: Academic Journal
Source(s): Molecules, Vol 20, Iss 10, Pp 18031-18046 (2015)
Abstract: Most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or unchanged forms. Metabolic and pharmacokinetic studies are therefore necessary to understand the pharmacological mechanisms of polyphenols. Jumihaidokut...
Yokukansan and Yokukansankachimpihange Ameliorate Aggressive Behaviors in Rats with Cholinergic Degeneration in the Nucleus Basalis of Meynert
Publication Type: Academic Journal
Source(s): Frontiers in Pharmacology, Vol 8 (2017)
Abstract: Yokukansan (YKS) and yokukansankachimpihange (YKSCH) are traditional Japanese Kampo medicines. The latter comprises YKS along with the medicinal herbs Citrus unshiu peel and Pinellia tuber. Both of these Kampo medicines are indicated for the treatment ...
Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 12, Iss 3, p e0173113 (2017)
Abstract: Cancer cachexia (CC) is a multifactorial disease characterized by decreased food intake and loss of body weight due to reduced musculature with or without loss of fat mass. Patients with gastric cancer have a high incidence of cachexia. We previously e...
Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 12, Iss 11, p e0187937 (2017)
Abstract: Sex differences exist in the activation of the hypothalamic-pituitary-adrenal axis following exposure to stress, and the stress response is further affected by aging. This study was conducted to elucidate the mechanism of hypophagia in aged female mice...
A New Strategy Using Rikkunshito to Treat Anorexia and Gastrointestinal Dysfunction
Publication Type: Academic Journal
Source(s): Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Abstract: Because the clinical condition of gastrointestinal dysfunction, including functional dyspepsia, involves tangled combinations of pathologies, there are some cases of insufficient curative efficacy. Thus, traditional herbal medicines (Kampo medicines) u...
Yokukansan Increases 5-HT1A Receptors in the Prefrontal Cortex and Enhances 5-HT1A Receptor Agonist-Induced Behavioral Responses in Socially Isolated Mice
Publication Type: Academic Journal
Source(s): Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Abstract: The traditional Japanese medicine yokukansan has an anxiolytic effect, which occurs after repeated administration. In this study, to investigate the underlying mechanisms, we examined the effects of repeated yokukansan administration on serotonin 1A (5...
Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 10, Iss 7, p e0133159 (2015)
Abstract: Rikkunshito, a traditional Japanese (Kampo) medicine, has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux. This study investigated the exposure and pharmacokinetics of the ingredients of rikk...
Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex
Publication Type: Academic Journal
Source(s): Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Rikkunshito Ameliorates Cancer Cachexia Partly through Elevation of Glucarate in Plasma
Publication Type: Academic Journal
Source(s): Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Abstract: Cancer cachexia, which is characterized by decreased food intake, weight loss and systemic inflammation, increases patient’s morbidity and mortality. We previously showed that rikkunshito (RKT), a Japanese traditional herbal medicine (Kampo), ameliorat...