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Advanced Search Results For "Usui, Noriyoshi"

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 "Usui, Noriyoshi"
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Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight

Publication Type: Academic Journal

Source(s): Frontiers in Endocrinology, Vol 13 (2022)

Abstract: Methamphetamine (METH) is a psychostimulant drug that induces addiction. Previous epidemiological studies have demonstrated that maternal METH abuse during pregnancy causes low birthweight (LBW) in the offspring. As a source of essential nutrients, in ...

Neuroinflammation and Oxidative Stress in the Pathogenesis of Autism Spectrum Disorder

Publication Type: Academic Journal

Source(s): International Journal of Molecular Sciences, Vol 24, Iss 5487, p 5487 (2023)

Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by impairments in social communication, repetitive behaviors, restricted interests, and hyperesthesia/hypesthesia caused by genetic and/or environmental factors. In rec...

Prenatal Sex Hormone Exposure Is Associated with the Development of Autism Spectrum Disorder

Publication Type: Academic Journal

Source(s): International Journal of Molecular Sciences, Vol 24, Iss 2203, p 2203 (2023)

Abstract: Sexual differentiation is a major developmental process. Sex differences resulting from sexual differentiation have attracted the attention of researchers. Unraveling what contributes to and underlies sex differences will provide valuable insights into...

Genomic Strategies for Understanding the Pathophysiology of Autism Spectrum Disorder

Publication Type: Academic Journal

Source(s): Frontiers in Molecular Neuroscience, Vol 15 (2022)

Abstract: Recent breakthroughs in sequencing technology and technological developments have made it easier to analyze the entire human genome than ever before. In addition to disease-specific genetic mutations and chromosomal aberrations, epigenetic alterations ...

Evolution of the Human Brain Can Help Determine Pathophysiology of Neurodevelopmental Disorders

Publication Type: Academic Journal

Source(s): Frontiers in Neuroscience, Vol 16 (2022)

Abstract: The evolution of humans brought about a co-occurring evolution of the human brain, which is far larger and more complex than that of many other organisms. The brain has evolved characteristically in humans in many respects, including macro-and micro-an...

Social Communication of Maternal Immune Activation-Affected Offspring Is Improved by Si-Based Hydrogen-Producing Agent

Publication Type: Academic Journal

Source(s): Frontiers in Psychiatry, Vol 13 (2022)

Abstract: Maternal immune activation (MIA) is triggered by infection or autoimmune predisposition during pregnancy, and cytokines produced by MIA are transmitted through the placenta to the fetal brain, implicating at the onset risks and vulnerability for develo...

Prenatal Environment and Neurodevelopmental Disorders

Publication Type: Academic Journal

Source(s): Frontiers in Endocrinology, Vol 13 (2022)

Abstract: The internal and external environment of the mother during the developmental stages of the fetus affects the offspring’s health. According to the developmental origins of health and disease (DOHaD) theory, environmental factors influence the offspring ...

Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment

Publication Type: Academic Journal

Source(s): Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract: Abstract We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was inversely proportional to the patient’s p...

Zbtb16 regulates social cognitive behaviors and neocortical development

Publication Type: Academic Journal

Source(s): Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract: Abstract Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor cell proliferation and neuronal differentiation during development, however, how the function of ZBTB16 is involved in brain function and behaviors unkno...

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