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Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer’s Disease?
Publication Type: Academic Journal
Source(s): Nutrients, Vol 15, Iss 3004, p 3004 (2023)
Abstract: The nuclear liver X receptors (LXRα/β) and peroxisome proliferator-activated receptors (PPARα/γ) are involved in the regulation of multiple biological processes, including lipid metabolism and inflammation. The activation of these receptors has been fo...
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences, Vol 24, Iss 1290, p 1290 (2023)
Abstract: The nuclear receptors—liver X receptors (LXR α and β) are potential therapeutic targets in cardiovascular and neurodegenerative diseases because of their key role in the regulation of lipid homeostasis and inflammatory processes. Specific oxy(phyto)ste...
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease
Publication Type: Academic Journal
Source(s): Marine Drugs, Vol 19, Iss 190, p 190 (2021)
Abstract: We recently found that dietary supplementation with the seaweed Sargassum fusiforme, containing the preferential LXRβ-agonist 24(S)-saringosterol, prevented memory decline and reduced amyloid-β (Aβ) deposition in an Alzheimer’s disease (AD) mouse model...
Spontaneous index finger extensor tendon rupture in a SNAC wrist
Publication Type: Periodical
Source(s): Hand Surgery and Rehabilitation; September 2021, Vol. 40 Issue: 4 p524-528, 5p
Abstract: We present two recent cases of spontaneous rupture of both index finger extensor digitorum communis and extensor indices proprius tendons caused by a dorsal carpus osteophyte. Both patients had a history of scaphoid fracture non-union with evolution to...
The role of receptor MAS in microglia-driven retinal vascular development.
Publication Type: Academic Journal
Source(s): Angiogenesis; Nov2019, Vol. 22 Issue 4, p481-489, 9p
Abstract: Copyright of Angiogenesis is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email ...
Radiological measurement of trapezial dysplasia – variation of trapezial tilt and trapezial inclination
Publication Type: Periodical
Source(s): Hand Surgery and Rehabilitation; February 2021, Vol. 40 Issue: 1 p44-50, 7p
Abstract: Trapeziometacarpal instability is a well-known condition that could lead to trapeziometacarpal osteoarthritis. With the focus in the literature being on ligament insufficiency, bony deformity has received much less attention. Although trapezial tilt is...
Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease?
Publication Type: Academic Journal
Source(s): Nutrients. Jul2023, Vol. 15 Issue 13, p3004. 24p.
Abstract: The nuclear liver X receptors (LXRα/β) and peroxisome proliferator-activated receptors (PPARα/γ) are involved in the regulation of multiple biological processes, including lipid metabolism and inflammation. The activation of these receptors has been fo...
Reversible Temperature-Switching of Hydrogel Stiffness of Coassembled, Silk-Collagen-LikeHydrogels.
Publication Type: Academic Journal
Source(s): Biomacromolecules; Aug2015, Vol. 16 Issue 8, p2506-2513, 8p
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.
Publication Type: Academic Journal
Source(s): Diabetes; Mar2012, Vol. 61 Issue 3, p659-664, 6p
Abstract: Copyright of Diabetes is the property of American Diabetes Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download,...
The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease.
Publication Type: Academic Journal
Source(s): Acta Psychiatrica Scandinavica; Sep2011, Vol. 124 Issue 3, p184-192, 9p, 2 Diagrams, 2 Charts, 1 Graph
Abstract: Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, d...