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The rapid and highly parallel identification of antibodies with defined biological activities by SLISY
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract: The covid pandemic has highlighted the need for rapid antibody development. Here, authors develop an approach called SLISY, which uses NGS with phage display to simultaneously assess millions of clones to rapidly isolate specific antibodies against SAR...
Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects.
Publication Type: Academic Journal
Source(s): Biophysical Reviews; Mar2014, Vol. 6 Issue 1, p89-95, 7p
Abstract: Copyright of Biophysical Reviews is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or...
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract: Chimeric antigen receptor T cells in the clinic currently target cell-type-specific extracellular antigens on malignant cells. Here, authors engineer tumor-specific chimeric antigen receptor T cells that target human leukocyte antigen-presented neoanti...
Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Publication Type: Academic Journal
Source(s): Oncogene; 4/22/2010, Vol. 29 Issue 16, p2337-2345, 9p, 2 Diagrams, 3 Graphs
Abstract: Copyright of Oncogene is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email arti...
Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma.
Publication Type: Academic Journal
Source(s): Calcified Tissue International; Mar2001, Vol. 68 Issue 3, p151-155, 5p
Abstract: Copyright of Calcified Tissue International is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, d...
APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis.
Publication Type: Academic Journal
Source(s): Gut; Apr1997, Vol. 40 Issue 4, p521-525, 5p
Abstract: Copyright of Gut is the property of BMJ Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email arti...
Germline SMAD4 or BMPRIA mutations and phenotype of juvenile polyposis.
Publication Type: Academic Journal
Source(s): Annals of Surgical Oncology: An Oncology Journal for Surgeons; Nov2002, Vol. 9 Issue 9, p901-906, 6p
Abstract: Copyright of Annals of Surgical Oncology: An Oncology Journal for Surgeons is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permissi...
Protein factor(s) from mitotic CHO cells induce meiotic maturation in Xenopus laevisoocytes
Publication Type: Periodical
Source(s): FEBS Letters; January 1980, Vol. 109 Issue: 2 p233-238, 6p
Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected].
Publication Type: Academic Journal
Source(s): JAMA: Journal of the American Medical Association; 6/2/89, Vol. 261 Issue 21, p3099-3103, 5p
Abstract: Copyright of JAMA: Journal of the American Medical Association is the property of American Medical Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permiss...
Different scaling of linear models and deep learning in UKBiobank brain images versus machine-learning datasets
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract: Schulz et al. systematically benchmark performance scaling with increasingly sophisticated prediction algorithms and with increasing sample size in reference machine-learning and biomedical datasets. Complicated nonlinear intervariable relationships re...