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Advanced Search Results For "Vumbaca G"

1 - 10 of 12 results for
 "Vumbaca G"
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Transitions from Compulsory Detention to Community-Based Treatment: No Transparency without Data, No Accountability without Independent Evaluations.

Publication Type: Academic Journal

Source(s): Health and human rights [Health Hum Rights] 2022 Jun; Vol. 24 (1), pp. 179-181.

Abstract: Competing Interests: Competing interests: None declared.

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Transcription Factor Activation Profiles (TFAP) identify compounds promoting differentiation of Acute Myeloid Leukemia cell lines.

Publication Type: Academic Journal

Source(s): Cell death discovery [Cell Death Discov] 2022 Jan 10; Vol. 8 (1), pp. 16. Date of Electronic Publication: 2022 Jan 10.

Abstract: Repurposing of drugs for new therapeutic use has received considerable attention for its potential to limit time and cost of drug development. Here we present a new strategy to identify chemicals that are likely to promote a desired phenotype. We used ...

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Characterization of the Skeletal Muscle Secretome Reveals a Role for Extracellular Vesicles and IL1α/IL1β in Restricting Fibro/Adipogenic Progenitor Adipogenesis.

Publication Type: Academic Journal

Source(s): Biomolecules [Biomolecules] 2021 Aug 08; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 08.

Abstract: Repeated mechanical stress causes injuries in the adult skeletal muscle that need to be repaired. Although muscle regeneration is a highly efficient process, it fails in some pathological conditions, compromising tissue functionality. This may be cause...

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A Resource for the Network Representation of Cell Perturbations Caused by SARS-CoV-2 Infection.

Publication Type: Academic Journal

Source(s): Genes [Genes (Basel)] 2021 Mar 22; Vol. 12 (3). Date of Electronic Publication: 2021 Mar 22.

Abstract: The coronavirus disease 2019 (COVID-19) pandemic has caused more than 2.3 million casualties worldwide and the lack of effective treatments is a major health concern. The development of targeted drugs is held back due to a limited understanding of the ...

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Skeletal Muscle Subpopulation Rearrangements upon Rhabdomyosarcoma Development through Single-Cell Mass Cytometry.

Publication Type: Academic Journal

Source(s): Journal of clinical medicine [J Clin Med] 2021 Feb 17; Vol. 10 (4). Date of Electronic Publication: 2021 Feb 17.

Abstract: The embryonal rhabdomyosarcoma (eRMS) is a soft tissue sarcoma commonly affecting the head and neck, the extremities and the genitourinary tract. To contribute to revealing the cell types that may originate this tumor, we exploited mass cytometry, a si...

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SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors.

Publication Type: Academic Journal

Source(s): Cell death & disease [Cell Death Dis] 2021 Jan 25; Vol. 12 (1), pp. 122. Date of Electronic Publication: 2021 Jan 25.

Abstract: The term micro-heterogeneity refers to non-genetic cell to cell variability observed in a bell-shaped distribution of the expression of a trait within a population. The contribution of micro-heterogeneity to physiology and pathology remains largely unc...

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Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2020 Mar 24; Vol. 10 (1), pp. 5363. Date of Electronic Publication: 2020 Mar 24.

Abstract: Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-physiological contexts (myopathies, atrophy, aging) FAPs cause fibrotic a...

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Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration.

Publication Type: Academic Journal

Source(s): Frontiers in physiology [Front Physiol] 2019 Sep 27; Vol. 10, pp. 1216. Date of Electronic Publication: 2019 Sep 27 (Print Publication: 2019).

Abstract: Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell-cell interactions and/or parac...

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Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis.

Publication Type: Academic Journal

Source(s): Life science alliance [Life Sci Alliance] 2019 Jun 25; Vol. 2 (3). Date of Electronic Publication: 2019 Jun 25 (Print Publication: 2019).

Abstract: Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis and fatty infiltrations. Here we show that the NOTCH pathway negati...

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Metformin Delays Satellite Cell Activation and Maintains Quiescence.

Publication Type: Academic Journal

Source(s): Stem cells international [Stem Cells Int] 2019 Apr 24; Vol. 2019, pp. 5980465. Date of Electronic Publication: 2019 Apr 24 (Print Publication: 2019).

Abstract: The regeneration of the muscle tissue relies on the capacity of the satellite stem cell (SC) population to exit quiescence, divide asymmetrically, proliferate, and differentiate. In age-related muscle atrophy (sarcopenia) and several dystrophies, regen...

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