Advanced Search Results For "WRIGHT, CRAIG"
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Multiparty Reach and Frequency Histogram: Private, Secure, and Practical
Publication Type: Academic Journal
Source(s): Proceedings on Privacy Enhancing Technologies, Vol 2022, Iss 1, Pp 373-395 (2022)
Abstract: Consider the setting where multiple parties each hold a multiset of users and the task is to estimate the reach (i.e., the number of distinct users appearing across all parties) and the frequency histogram (i.e., fraction of users appearing a given num...
GWAS Explorer: an open-source tool to explore, visualize, and access GWAS summary statistics in the PLCO Atlas
Publication Type: Academic Journal
Source(s): Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract: Abstract The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a prospective cohort study of nearly 155,000 U.S. volunteers aged 55–74 at enrollment in 1993–2001. We developed the PLCO Atlas Project, a large resource for multi-tra...
Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract: RAS mutations are commonly found in multiple myeloma (MM). Here, the authors show that oncogenic RAS mutations activate mTORC1 signalling in MM and combining mTORC1 and MEK/ERK inhibitors synergize to improve survival in preclinical models.
Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 12, Iss 11 (2022)
Abstract: Objectives Hospital-acquired pressure injuries (PIs) are a source of morbidity and mortality, and many are potentially preventable.Design This study prospectively evaluated the prevalence and the associated factors of PIs in adult critical care patient...
Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
Publication Type: Academic Journal
Source(s): BMJ Global Health, Vol 7, Iss 10 (2022)
Abstract: Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pan...
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface.
Publication Type: Academic Journal
Source(s): PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010791 (2022)
Abstract: Trypanosoma vivax is a unicellular hemoparasite, and a principal cause of animal African trypanosomiasis (AAT), a vector-borne and potentially fatal livestock disease across sub-Saharan Africa. Previously, we identified diverse T. vivax-specific genes ...
Family-Based Telehealth Initiative to Improve Nutrition and Physical Activity for Children With Obesity and Its Utility During COVID-19: A Mixed Methods Evaluation
Publication Type: Academic Journal
Source(s): Frontiers in Nutrition, Vol 9 (2022)
Abstract: Guidelines recommend primary care providers refer children with obesity to behavioral interventions, but given limited program availability, access, and parental engagement, referrals remain rare. We developed telehealth coaching interventions for fami...
An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia: the Journeying through Dementia RCT
Publication Type: Academic Journal
Source(s): Health Technology Assessment, Vol 26, Iss 24 (2022)
Abstract: Background: There are few effective interventions for dementia. Aim: To determine the clinical effectiveness and cost-effectiveness of an intervention to promote self-management, independence and self-efficacy in people with early-stage dementia. Objec...
The effects of normobaric hypoxia on the leukocyte responses to resistance exercise
Publication Type: Academic Journal
Source(s): Biology of Sport, Vol 40, Iss 1, Pp 101-109 (2022)
Abstract: There is growing interest in the use of systemic hypoxia to improve the training adaptations to resistance exercise. Hypoxia is a well-known stimulator of the immune system, yet the leukocyte responses to this training modality remain uncharacterised. ...
Multicenter, randomized, double‐blinded, placebo‐controlled study of rabacfosadine in dogs with lymphoma
Publication Type: Academic Journal
Source(s): Journal of Veterinary Internal Medicine, Vol 36, Iss 1, Pp 215-226 (2022)
Abstract: Abstract Background Rabacfosadine (RAB, Tanovea‐CA1) is a novel chemotherapy agent conditionally approved for the treatment of lymphoma in dogs. Hypothesis/Objectives To determine the efficacy and safety of RAB in dogs with lymphoma. Animals One hundre...