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Advanced Search Results For "Wang, Ming���Shan"

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 "Wang, Ming���Shan"
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Unveiling the functional and evolutionary landscape of RNA editing in chicken using genomics and transcriptomics

Publication Type: Academic Journal

Source(s): Zoological Research, Vol 43, Iss 6, Pp 1011-1022 (2022)

Abstract: The evolutionary and functional features of RNA editing are well studied in mammals, cephalopods, and insects, but not in birds. Here, we integrated transcriptomic and whole-genomic analyses to exhaustively characterize the expansive repertoire of aden...

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Genome-wide scan for selection signatures and genes related to heat tolerance in domestic chickens in the tropical and temperate regions in Asia

Publication Type: Academic Journal

Source(s): Poultry Science, Vol 101, Iss 7, Pp 101821- (2022)

Abstract: ABSTRACT: Heat stress is one of the major environmental stressors challenging the global poultry industry. Identifying the genes responsible for heat tolerance is fundamentally important for direct breeding programs. To uncover the genetic basis underl...

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Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription

Publication Type: Academic Journal

Source(s): Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)

Abstract: Abstract Background Epidemiological studies have confirmed that abnormal circadian rhythms are associated with tumorigenesis in breast cancer. However, few studies have investigated the pathological roles of rhythm genes in breast cancer progression. I...

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Interleukin 22 and its association with neurodegenerative disease activity

Publication Type: Academic Journal

Source(s): Frontiers in Pharmacology, Vol 13 (2022)

Abstract: It is worth noting that neuroinflammation is well recognized as a symptom of neurodegenerative diseases (NDs). The regulation of neuroinflammation becomes an attractive focus for innovative ND treatment technologies. There is evidence that IL-22 is ass...

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Construction Dispute Potentials: Mechanism versus Empiricism in Artificial Neural Networks

Publication Type: Academic Journal

Source(s): Sustainability, Vol 14, Iss 15239, p 15239 (2022)

Abstract: The booming development of neural network algorithms has shifted the research focus in the field of construction project management from causal investigation to statistical approximation and hence from mechanistic models to empirical models. This paper...

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Circulating Glycan Monosaccharide Composite-Based Biomarker Diagnoses Colorectal Cancer at Early Stages and Predicts Prognosis

Publication Type: Academic Journal

Source(s): Frontiers in Oncology, Vol 12 (2022)

Abstract: IntroductionEarly diagnosis could lead to a cure of colorectal cancer (CRC). Since CRC is related to aging and lifestyles, we tested if the environmental information-enriched monosaccharide composite (MC) of circulating glycans could serve as an early ...

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Genomes reveal selective sweeps in kiang and donkey for high-altitude adaptation

Publication Type: Academic Journal

Source(s): Zoological Research, Vol 42, Iss 4, Pp 450-460 (2021)

Abstract: Over the last several hundred years, donkeys have adapted to high-altitude conditions on the Tibetan Plateau. Interestingly, the kiang, a closely related equid species, also inhabits this region. Previous reports have demonstrated the importance of spe...

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Large-scale genomic analysis reveals the genetic cost of chicken domestication

Publication Type: Academic Journal

Source(s): BMC Biology, Vol 19, Iss 1, Pp 1-16 (2021)

Abstract: Abstract Background Species domestication is generally characterized by the exploitation of high-impact mutations through processes that involve complex shifting demographics of domesticated species. These include not only inbreeding and artificial sel...

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Evaluating the Risk of Breast Cancer Recurrence and Metastasis After Adjuvant Tamoxifen Therapy by Integrating Polymorphisms in Cytochrome P450 Genes and Clinicopathological Characteristics

Publication Type: Academic Journal

Source(s): Frontiers in Oncology, Vol 11 (2021)

Abstract: Tamoxifen (TAM) is the most commonly used adjuvant endocrine drug for hormone receptor-positive (HR+) breast cancer patients. However, how to accurately evaluate the risk of breast cancer recurrence and metastasis after adjuvant TAM therapy is still a ...

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Revisiting the evolutionary history of domestic and wild ducks based on genomic analyses

Publication Type: Academic Journal

Source(s): Zoological Research, Vol 42, Iss 1, Pp 43-50 (2021)

Abstract: Although domestic ducks have been important poultry species throughout human history, their origin remains enigmatic, with mallards and/or Chinese spot-billed ducks being proposed as the direct wild ancestor(s) of domestic ducks. Here, we analyzed 118 ...

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