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Advanced Search Results For "Ziegler, Hanne L."

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 "Ziegler, Hanne L."
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19α-Hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum.

Publication Type: Academic Journal

Source(s): Natural Product Research; Aug2009, Vol. 23 Issue 12, p1108-1111, 4p, 1 Graph

Abstract: Copyright of Natural Product Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, do...

Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure–activity relationships for betulinic acid analogues

Publication Type: Academic Journal

Source(s): Bioorganic & Medicinal Chemistry. Jan2004, Vol. 12 Issue 1, p119. 9p.

Abstract: The natural triterpene betulinic acid and its analogues (betulinic aldehyde, lupeol, betulin, methyl betulinate and betulinic acid amide) caused concentration-dependent alterations of erythrocyte membrane shape towards stomatocytes or echinocytes accor...

The Antiparasitic Compound Licochalcone A Is a Potent Echinocytogenic Agent That Modifies the Erythrocyte Membrane in the Concentration Range Where Antiplasmodial Activity Is Observed

Publication Type: Periodical

Source(s): Antimicrobial Agents and Chemotherapy; October 2004, Vol. 48 Issue: 10 p4067-4071, 5p

Abstract: ABSTRACTThe well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparumcultures, the in vitro antiplasmodial ...

In Vitro Plasmodium falciparumDrug Sensitivity Assay: Inhibition of Parasite Growth by Incorporation of Stomatocytogenic Amphiphiles into the Erythrocyte Membrane

Publication Type: Periodical

Source(s): Antimicrobial Agents and Chemotherapy; May 2002, Vol. 46 Issue: 5 p1441-1446, 6p

Abstract: ABSTRACTLupeol, which shows in vitro inhibitory activity against Plasmodium falciparum3D7 strain with a 50% inhibitory concentration (IC50) of 27.7 ± 0.5 μM, was shown to cause a transformation of the human erythrocyte shape toward that of stomatocytes...

Combining HPLC-PDA-MS-SPE-NMR with Circular Dichroism for Complete Natural Product Characterization in Crude Extracts: Levorotatory Gossypol in Thespesia danis

Publication Type: Periodical

Source(s): Journal of Natural Products; February 2008, Vol. 71 Issue: 4 p516-519, 4p

Abstract: Despite recent demonstration of the power of HPLC-PDA-MS-SPE-NMR (high-performance liquid chromatography−photodiode-array detection−mass spectrometry−solid-phase extraction−nuclear magnetic resonance) in structure determination of natural products dire...