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Advanced Search Results For "van de Waarenburg MPH"

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 "van de Waarenburg MPH"
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Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study.

Publication Type: Academic Journal

Source(s): Diabetologia [Diabetologia] 2023 Jan; Vol. 66 (1), pp. 213-222. Date of Electronic Publication: 2022 Sep 17.

Abstract: Aims/hypothesis: Serum sex hormone-binding globulin (SHBG) has been proposed to act as a hepatokine that contributes to the extrahepatic complications observed in non-alcoholic fatty liver disease (NAFLD). However, it remains uncertain whether serum SH...

Association of α-Dicarbonyls and Advanced Glycation End Products with Insulin Resistance in Non-Diabetic Young Subjects: A Case-Control Study.

Publication Type: Academic Journal

Source(s): Nutrients [Nutrients] 2022 Nov 21; Vol. 14 (22). Date of Electronic Publication: 2022 Nov 21.

Abstract: α-Dicarbonyls and advanced glycation end products (AGEs) may contribute to the pathogenesis of insulin resistance by a variety of mechanisms. To investigate whether young insulin-resistant subjects present markers of increased dicarbonyl stress, we det...

Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2021 Nov 22; Vol. 11 (1), pp. 22675. Date of Electronic Publication: 2021 Nov 22.

Abstract: There has been increasing interest in finding non-invasive biomarkers for neurodegenerative diseases such as Alzheimer's disease (AD). This observational study investigated AD-specific biomarkers in tear fluid. Tear fluid was collected from a total of ...

Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility.

Publication Type: Academic Journal

Source(s): Food research international (Ottawa, Ont.) [Food Res Int] 2021 Sep; Vol. 147, pp. 110547. Date of Electronic Publication: 2021 Jun 18.

Abstract: Scope: Dietary advanced glycation endproducts (AGEs) are associated with negative biological effects, possibly due to accumulation in plasma and tissues and through modulation of inflammation and gut microbiota. Whether these biological consequences ar...

Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.

Publication Type: Academic Journal

Source(s): Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2021 Sep; Vol. 38 (9), pp. e14405. Date of Electronic Publication: 2020 Oct 16.

Abstract: Aim: Angiotensin receptor blockers (ARBs) reduce vascular complications in diabetes independently of blood pressure. Experimental studies suggested that ARBs may restore the detoxifying enzyme glyoxalase 1, thereby lowering dicarbonyls such as methylgl...

Hepatic Fat Content and Liver Enzymes Are Associated with Circulating Free and Protein-Bound Advanced Glycation End Products, Which Are Associated with Low-Grade Inflammation: The CODAM Study.

Publication Type: Academic Journal

Source(s): Journal of diabetes research [J Diabetes Res] 2019 May 14; Vol. 2019, pp. 6289831. Date of Electronic Publication: 2019 May 14 (Print Publication: 2019).

Abstract: Advanced glycation end products (AGEs) accumulate in fatty livers and may contribute to low-grade inflammation (LGI), potentially via their receptor, RAGE. It is unknown if the AGE accumulation in fatty livers results in elevated circulating AGEs. In a...

RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr -/- mice.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2018 Oct 15; Vol. 8 (1), pp. 15256. Date of Electronic Publication: 2018 Oct 15.

Abstract: Non-alcoholic fatty liver disease is a spectrum of liver diseases ranging from steatosis only to non-alcoholic steatohepatitis (NASH). The latter is characterized by hepatic inflammation, which increases the risk of cardiovascular disease. It is poorly...

Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men.

Publication Type: Academic Journal

Source(s): The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2018 Feb 01; Vol. 103 (2), pp. 759-767.

Abstract: Context: Impaired insulin-mediated muscle microvascular recruitment (IMMR) may add to the development of insulin resistance and hypertension. Increased aldosterone levels have been linked to these obesity-related complications in severely to morbidly o...