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Modulating Nanodroplet Formation En Route to Fibrillization of Amyloid Peptides with Designed Flanking Sequences.
Publication Type: Academic Journal
Source(s): Biomacromolecules [Biomacromolecules] 2022 Oct 10; Vol. 23 (10), pp. 4179-4191. Date of Electronic Publication: 2022 Sep 22.
Abstract: Soluble oligomers populating early amyloid aggregation can be regarded as nanodroplets of liquid-liquid phase separation (LLPS). Amyloid peptides typically contain hydrophobic aggregation-prone regions connected by hydrophilic linkers and flanking sequ...
Literacy critical to heart failure management: a scoping review.
Publication Type: Academic Journal
Source(s): Heart failure reviews [Heart Fail Rev] 2021 Nov; Vol. 26 (6), pp. 1413-1419.
Abstract: Heart failure is a complex clinical syndrome most commonly encountered among older adults. This complex clinical syndrome is associated with poor health outcomes such as frequent admissions and mortality. These adverse outcomes are commonly associated ...
Hyperglycaemia, ejection fraction and the risk of heart failure or cardiovascular death in patients with type 2 diabetes and a recent acute coronary syndrome.
Publication Type: Academic Journal
Source(s): European journal of heart failure [Eur J Heart Fail] 2020 Jul; Vol. 22 (7), pp. 1133-1143. Date of Electronic Publication: 2020 Mar 25.
Abstract: Aims: Chronic hyperglycaemia, assessed by elevated glycated haemoglobin (A1C), is a known risk factor for heart failure (HF) and cardiovascular (CV) death among subjects with diabetes. Whether this risk varies with left ventricular ejection fraction (L...
Can we trust a smartwatch ECG? Potential and limitations.
Publication Type: Academic Journal
Source(s): European journal of heart failure [Eur J Heart Fail] 2021 Jun; Vol. 23 (6), pp. 850-853. Date of Electronic Publication: 2021 May 07.
How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).
Publication Type: Academic Journal
Source(s): European journal of heart failure [Eur J Heart Fail] 2020 Mar; Vol. 22 (3), pp. 391-412. Date of Electronic Publication: 2020 Mar 05.
Abstract: Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF) remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA-PEFF diagnostic algorithm'. Step 1 (P=Pre-test assessment) is typically performed in...
Neuroinflammation in heart failure: new insights for an old disease.
Publication Type: Academic Journal
Source(s): The Journal of physiology [J Physiol] 2020 Jan; Vol. 598 (1), pp. 33-59. Date of Electronic Publication: 2019 Dec 03.
Abstract: Heart failure (HF) is a complex clinical syndrome affecting roughly 26 million people worldwide. Increased sympathetic drive is a hallmark of HF and is associated with disease progression and higher mortality risk. Several mechanisms contribute to enha...
Association between prehospital arterial hypercapnia and mortality in acute heart failure: a retrospective cohort study.
Publication Type: Academic Journal
Source(s): BMC emergency medicine [BMC Emerg Med] 2021 Nov 06; Vol. 21 (1), pp. 130. Date of Electronic Publication: 2021 Nov 06.
Abstract: Background: Acute Heart Failure (AHF) is a potentially lethal pathology and is often encountered in the prehospital setting. Although an association between prehospital arterial hypercapnia in AHF patients and admission in high-dependency and intensive...
Review of the impact of donor characteristics on pediatric heart transplant outcomes.
Publication Type: Academic Journal
Source(s): Pediatric transplantation [Pediatr Transplant] 2020 May; Vol. 24 (3), pp. e13680. Date of Electronic Publication: 2020 Mar 21.
Abstract: Heart transplantation (HTx) is a treatment option for end-stage heart failure in children. HTx is limited by the availability and acceptability of donor hearts. Refusal of donor hearts has been reported to be common with reasons for refusal including p...
Assessing the evidence-practice gap for heart failure in China: the Heart Failure Registry of Patient Outcomes (HERO) study design and baseline characteristics.
Publication Type: Academic Journal
Source(s): European journal of heart failure [Eur J Heart Fail] 2020 Apr; Vol. 22 (4), pp. 646-660. Date of Electronic Publication: 2019 Dec 09.
Abstract: Background: Registry studies in high-income countries have defined contemporary management of heart failure (HF), but few such data exist in the large aging population of China. We report the study design and baseline characteristics of the Heart Failu...
Cardiovascular morbidity and long term mortality associated with in hospital small increases of serum creatinine.
Publication Type: Academic Journal
Source(s): Journal of nephrology [J Nephrol] 2018 Feb; Vol. 31 (1), pp. 71-77. Date of Electronic Publication: 2017 May 31.
Abstract: Background: The cardiovascular risk associated with an increase in serum creatinine below the acute kidney injury (AKI) threshold, during hospitalization, has not been studied in depth. We assessed patients' features and outcomes associated with these ...