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Simultaneous Determination of Aesculin, Aesculetin, Fraxetin, Fraxin and Polydatin in Beagle Dog Plasma by UPLC-ESI-MS/MS and Its Application in a Pharmacokinetic Study after Oral Administration Extracts of Ledum palustre L.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2018 Sep 07; Vol. 23 (9). Date of Electronic Publication: 2018 Sep 07.
Abstract: A rapid, simple and sensitive ultra-performance liquid chromatography-electrospray-ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed and validated for the simultaneous determination of aesculin, aesculetin, fraxetin, fraxin and ...
UHPLC-MS/MS Quantification Combined with Chemometrics for Comparative Analysis of Different Batches of Raw, Wine-Processed, and Salt-Processed Radix Achyranthis Bidentatae.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2018 Mar 26; Vol. 23 (4). Date of Electronic Publication: 2018 Mar 26.
Abstract: An accurate and reliable method using ultra-high performance liquid chromatography combined with triple quadrupole tandem mass spectrometry (UHPLC-MS/MS) was established for simultaneous quantification of five major bioactive analytes in raw, wine-proc...
Decentral gene expression analysis: analytical validation of the Endopredict genomic multianalyte breast cancer prognosis test.
Publication Type: Academic Journal
Source(s): BMC cancer [BMC Cancer] 2012 Oct 05; Vol. 12, pp. 456. Date of Electronic Publication: 2012 Oct 05.
Abstract: Background: EndoPredict (EP) is a clinically validated multianalyte gene expression test to predict distant metastasis in ER-positive, HER2-negative breast cancer treated with endocrine therapy alone. The test is based on the combined analysis of 12 ge...
Validation of quantitative polymerase chain reaction assays for measuring cytokine expression in equine macrophages.
Publication Type: Academic Journal
Source(s): Journal of immunological methods [J Immunol Methods] 2007 Dec 01; Vol. 328 (1-2), pp. 59-69. Date of Electronic Publication: 2007 Sep 04.
Abstract: The study of the equine immune system and inflammatory responses, by measuring cytokine expression, can provide important insight into disease pathogenesis in the horse. A set of quantitative real-time polymerase chain reaction (QPCR) assays for the eq...
A UPLC-MS Method for Simultaneous Determination of Geniposidic Acid, Two Lignans and Phenolics in Rat Plasma and its Application to Pharmacokinetic Studies of Eucommia ulmoides Extract in Rats.
Publication Type: Academic Journal
Source(s): European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2016 Oct; Vol. 41 (5), pp. 595-603.
Abstract: The bark of Eucommia ulmoides is a well-known Chinese herbal medicine that is used to regulate blood pressure and reduce blood sugar and fats, as well as an antioxidant and antimicrobial agent. Here we describe the development of a sensitive ultrahigh ...
An LC-MS/MS method for the simultaneous determination of lycorine and galanthamine in rat plasma and its application to pharmacokinetic study of Lycoris radiata extract in rats.
Publication Type: Academic Journal
Source(s): Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban [J Huazhong Univ Sci Technolog Med Sci] 2014 Dec; Vol. 34 (6), pp. 861-868. Date of Electronic Publication: 2014 Dec 06.
Abstract: A rapid, sensitive, and selective liquid chromatography-tandem mass spectrometry was developed for the simultaneous determination of lycorine and galanthamine, two major constituents in Lycoris radiata extract, in rat plasma. Liquid-liquid extraction w...
A LC-ESI-MS method for the simultaneous determination of madecassoside and its metabolite madecassic acid in rat plasma: comparison pharmacokinetics in normal and collagen-induced arthritic rats.
Publication Type: Academic Journal
Source(s): Chinese journal of natural medicines [Chin J Nat Med] 2014 Dec; Vol. 12 (12), pp. 943-51.
Abstract: To develop a simple and highly sensitive high performance liquid chromatography with electrospray ionization mass spectrometric (LC-ESI-MS) method for the simultaneous determination of madecassoside and its major metabolite madecassic acid in rat plasm...
Analysis of hupehenine in the total alkaloids from Fritillaria hupehensis by HPLC-ELSD.
Publication Type: Academic Journal
Source(s): Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban [J Huazhong Univ Sci Technolog Med Sci] 2008 Feb; Vol. 28 (1), pp. 118-20.
Abstract: A reverse-phase high pressure liquid chromatography (HPLC) method with evaporative light scattering detection (ELSD) has been developed for the quantitative analysis of hupehenine in the total alkaloids from Fritillaria hupehensis. Samples were analyze...