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    • How mouse RAG recombinase avoids DNA transposition.

    Publication Type: Academic Journal

    Source(s): Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Feb; Vol. 27 (2), pp. 127-133. Date of Electronic Publication: 2020 Feb 03.

    Authors:

    Abstract: The RAG1-RAG2 recombinase (RAG) cleaves DNA to initiate V(D)J recombination, but RAG also belongs to the RNH-type transposase family. To learn how RAG-catalyzed transposition is inhibited in developing lymphocytes, we determined the structure of a DNA-...

    Self-assembled DNA nanostructures for distance-dependent multivalent ligand-protein binding.

    Publication Type: Academic Journal

    Source(s): Nature nanotechnology [Nat Nanotechnol] 2008 Jul; Vol. 3 (7), pp. 418-22. Date of Electronic Publication: 2008 Jun 22.

    Authors:

    Abstract: An important goal of nanotechnology is to assemble multiple molecules while controlling the spacing between them. Of particular interest is the phenomenon of multivalency, which is characterized by simultaneous binding of multiple ligands on one biolog...

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