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Assessing the potential of surface-immobilized molecular logic machines for integration with solid state technology.

Publication Type: Academic Journal

Source(s): Bio Systems [Biosystems] 2016 Aug; Vol. 146, pp. 3-9. Date of Electronic Publication: 2016 May 18.

Abstract: Molecular computation with DNA has great potential for low power, highly parallel information processing in a biological or biochemical context. However, significant challenges remain for the field of DNA computation. New technology is needed to allow ...

How mouse RAG recombinase avoids DNA transposition.

Publication Type: Academic Journal

Source(s): Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Feb; Vol. 27 (2), pp. 127-133. Date of Electronic Publication: 2020 Feb 03.

Authors:

Abstract: The RAG1-RAG2 recombinase (RAG) cleaves DNA to initiate V(D)J recombination, but RAG also belongs to the RNH-type transposase family. To learn how RAG-catalyzed transposition is inhibited in developing lymphocytes, we determined the structure of a DNA-...

Au nanorod helical superstructures with designed chirality.

Publication Type: Academic Journal

Source(s): Journal of the American Chemical Society [J Am Chem Soc] 2015 Jan 14; Vol. 137 (1), pp. 457-62. Date of Electronic Publication: 2014 Dec 29.

Authors:

Abstract: A great challenge for nanotechnology is to controllably organize anisotropic nanomaterials into well-defined three-dimensional superstructures with customized properties. Here we successfully constructed anisotropic Au nanorod (AuNR) helical superstruc...

Self-assembled DNA nanostructures for distance-dependent multivalent ligand-protein binding.

Publication Type: Academic Journal

Source(s): Nature nanotechnology [Nat Nanotechnol] 2008 Jul; Vol. 3 (7), pp. 418-22. Date of Electronic Publication: 2008 Jun 22.

Authors:

Abstract: An important goal of nanotechnology is to assemble multiple molecules while controlling the spacing between them. Of particular interest is the phenomenon of multivalency, which is characterized by simultaneous binding of multiple ligands on one biolog...

Improved longitudinal [(18)F]-AV45 amyloid PET by white matter reference and VOI-based partial volume effect correction.

Publication Type: Academic Journal

Source(s): NeuroImage [Neuroimage] 2015 Mar; Vol. 108, pp. 450-9. Date of Electronic Publication: 2014 Dec 04.

Abstract: Amyloid positron-emission-tomography (PET) offers an important research and diagnostic tool for investigating Alzheimer's disease (AD). The majority of amyloid PET studies have used the cerebellum as a reference region, and clinical studies have not ac...

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