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A harmonized and standardized in vitro approach produces reliable results on silver nanoparticles toxicity in different cell lines.
Publication Type: Academic Journal
Source(s): Journal of applied toxicology : JAT [J Appl Toxicol] 2021 Dec; Vol. 41 (12), pp. 1980-1997. Date of Electronic Publication: 2021 May 12.
Abstract: Despite the widespread use of silver nanoparticles (AgNPs) in different fields and the amount of investigations available, to date, there are many contradictory results on their potential toxicity. In the present study, extensively characterized 20-nm ...
Metallic, metal oxide, and metalloid nanoparticles toxic effects on freshwater microcrustaceans: An update and basis for the use of new test species.
Publication Type: Academic Journal
Source(s): Water environment research : a research publication of the Water Environment Federation [Water Environ Res] 2021 Nov; Vol. 93 (11), pp. 2505-2526. Date of Electronic Publication: 2021 Oct 03.
Abstract: In this article, we performed a literature review on the metallic, metal oxide, and metalloid nanoparticles (NP) effects on freshwater microcrustaceans, specifically focusing on (i) the main factors influencing the NP toxicity and (ii) their main ecoto...
Spatial omics and multiplexed imaging to explore cancer biology.
Publication Type: Academic Journal
Source(s): Nature methods [Nat Methods] 2021 Sep; Vol. 18 (9), pp. 997-1012. Date of Electronic Publication: 2021 Aug 02.
Abstract: Understanding intratumoral heterogeneity-the molecular variation among cells within a tumor-promises to address outstanding questions in cancer biology and improve the diagnosis and treatment of specific cancer subtypes. Single-cell analyses, especiall...
Imaging Transcriptomics in Neurodegenerative Diseases.
Publication Type: Academic Journal
Source(s): Journal of neuroimaging : official journal of the American Society of Neuroimaging [J Neuroimaging] 2021 Mar; Vol. 31 (2), pp. 244-250. Date of Electronic Publication: 2020 Dec 26.
Abstract: Imaging transcriptomics investigates the relationship between neuroanatomical/neuroimaging features and gene expression. The spatial and temporal distribution of the expressed genes and their pattern of spreading over time can contribute to elucidating...
Quantification of titanium dioxide nanoparticles in human urine by single-particle ICP-MS.
Publication Type: Academic Journal
Source(s): Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Jan; Vol. 413 (1), pp. 171-181. Date of Electronic Publication: 2020 Oct 29.
Abstract: The increasing use of titanium dioxide nanoparticles in daily use consumer products such as cosmetics, personal care products, food additives, and even medicine has led to growing concerns regarding human safety. It would be ideal to track exposure to ...
Screening on platelet LncRNA expression profile discloses novel residual platelet reactivity biomarker.
Publication Type: Academic Journal
Source(s): International journal of laboratory hematology [Int J Lab Hematol] 2020 Oct; Vol. 42 (5), pp. 661-668. Date of Electronic Publication: 2020 Jun 22.
Abstract: Introduction: Double antiplatelet therapy (DAPT) has wide inter-individual variabilities in coronary heart disease (CHD) patients' responses, which undermines the prognosis effect in clinical practice. Long noncoding RNAs (lncRNAs) have been reported t...
An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity.
Publication Type: Academic Journal
Source(s): PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Jun 24; Vol. 14 (6), pp. e0008366. Date of Electronic Publication: 2020 Jun 24 (Print Publication: 2020).
Abstract: Snakebite envenoming is a major neglected tropical disease that affects millions of people every year. The only effective treatment against snakebite envenoming consists of unspecified cocktails of polyclonal antibodies purified from the plasma of immu...
A fluorometric clenbuterol immunoassay based on the use of organic/inorganic hybrid nanoflowers modified with gold nanoclusters and artificial antigen.
Publication Type: Academic Journal
Source(s): Mikrochimica acta [Mikrochim Acta] 2018 Jul 07; Vol. 185 (8), pp. 366. Date of Electronic Publication: 2018 Jul 07.
Abstract: Organic/inorganic hybrid nanoflowers were synthesized from calcium phosphate and protein modified fluorescent gold nanoclusters and antigens. These nanoflowers are shown to be well suited labels for bioassay because they fulfill the functions of biolog...
Reverse engineering directed gene regulatory networks from transcriptomics and proteomics data of biomining bacterial communities with approximate Bayesian computation and steady-state signalling simulations.
Publication Type: Academic Journal
Source(s): BMC bioinformatics [BMC Bioinformatics] 2020 Jan 21; Vol. 21 (1), pp. 23. Date of Electronic Publication: 2020 Jan 21.
Abstract: Background: Network inference is an important aim of systems biology. It enables the transformation of OMICs datasets into biological knowledge. It consists of reverse engineering gene regulatory networks from OMICs data, such as RNAseq or mass spectro...
Transcriptome analysis of the key role of GAT2 gene in the hyper-accumulation of copper in the oyster Crassostrea angulata.
Publication Type: Academic Journal
Source(s): Scientific reports [Sci Rep] 2015 Dec 09; Vol. 5, pp. 17751. Date of Electronic Publication: 2015 Dec 09.
Abstract: One paradigm of oysters as the hyper-accumulators of many toxic metals is the inter-individual variation of metals, but the molecular mechanisms remain very elusive. A comprehensive analysis of the transcriptome of Crassostrea angulata was conducted to...