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Remarked suppression of Aβ 42 protomer-protomer dissociation reaction elucidated by molecular dynamics simulation.
Publication Type: Academic Journal
Source(s): Proteins [Proteins] 2022 Jul; Vol. 90 (7), pp. 1367-1375. Date of Electronic Publication: 2022 Feb 28.
Abstract: Multimeric protein complexes are molecular apparatuses to regulate biological systems and often determine their fate. Among proteins forming such molecular assemblies, amyloid proteins have drawn attention over a half-century since amyloid fibril forma...
Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction.
Publication Type: Academic Journal
Source(s): Pharmaceutics. Nov2022, Vol. 14 Issue 11, p2342. 19p.
Abstract: One of the pathological hallmarks of Alzheimer's disease (AD) is the formation of amyloid-β plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the inhibition of this enzyme could slow down the progression of amyloid-β ag...
Amyloid β, Lipid Metabolism, Basal Cholinergic System, and Therapeutics in Alzheimer's Disease.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 20, p12092-N.PAG. 32p.
Abstract: The presence of insoluble aggregates of amyloid β (Aβ) in the form of neuritic plaques (NPs) is one of the main features that define Alzheimer's disease. Studies have suggested that the accumulation of these peptides in the brain significantly contribu...
Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide.
Publication Type: Academic Journal
Source(s): Nano Research; Nov2019, Vol. 12 Issue 11, p2827-2834, 8p
Abstract: Copyright of Nano Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email...
Ratio of serum amyloid A to C‐reactive protein is constant in the same patients but differs greatly between patients with inflammatory diseases.
Publication Type: Academic Journal
Source(s): Scandinavian Journal of Immunology; Feb2022, Vol. 95 Issue 2, p1-9, 9p
Abstract: Copyright of Scandinavian Journal of Immunology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may prin...
Sticker-and-spacer model for amyloid beta condensation and fibrillation.
Publication Type: Academic Journal
Source(s): Frontiers in Molecular Neuroscience; 10/13/2022, Vol. 15, p1-16, 16p
Abstract: Copyright of Frontiers in Molecular Neuroscience is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users ma...
Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol.
Publication Type: Academic Journal
Source(s): Cell & Bioscience; 9/13/2023, Vol. 13 Issue 1, p1-23, 23p
Abstract: Copyright of Cell & Bioscience is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or em...
Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases.
Publication Type: Academic Journal
Source(s): Biochemical Journal; Aug2023, Vol. 480 Issue 15, p1217-1240, 24p
Abstract: Copyright of Biochemical Journal is the property of Portland Press Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download...
Serum Amyloid A 4 as a Common Marker of Persistent Inflammation in Patients with Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy.
Publication Type: Academic Journal
Source(s): Journal of Inflammation Research; Aug2023, Vol. 16, p3783-3797, 15p
Abstract: Copyright of Journal of Inflammation Research is the property of Dove Medical Press Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may...
Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Publication Type: Academic Journal
Source(s): FEBS Open Bio; Aug2023, Vol. 13 Issue 8, p1394-1404, 11p
Abstract: Copyright of FEBS Open Bio is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email...