Advanced Search Results For "ADHESION"
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Cardiac Differentiation Promotes Focal Adhesions Assembly through Vinculin Recruitment.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jan 26; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 26.
Abstract: Cells of the cardiovascular system are physiologically exposed to a variety of mechanical forces fundamental for both cardiac development and functions. In this context, forces generated by actomyosin networks and those transmitted through focal adhesi...
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation.
Publication Type: Academic Journal
Source(s): Biological psychiatry [Biol Psychiatry] 2023 Jan 15; Vol. 93 (2), pp. 187-196. Date of Electronic Publication: 2022 Jul 02.
Abstract: Background: Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated responses and mediating signals acr...
Selective Transcription Factor Blockade Reduces Human Retinal Endothelial Cell Expression of Intercellular Adhesion Molecule-1 and Leukocyte Binding.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Feb 07; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 07.
Abstract: The interaction between leukocytes and cytokine-activated retinal endothelium is an initiating step in non-infectious uveitis involving the posterior eye, mediated by cell adhesion molecules. However, because cell adhesion molecules are required for im...
Organization, dynamics and mechanoregulation of integrin-mediated cell-ECM adhesions.
Publication Type: Academic Journal
Source(s): Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2023 Feb; Vol. 24 (2), pp. 142-161. Date of Electronic Publication: 2022 Sep 27.
Abstract: The ability of animal cells to sense, adhere to and remodel their local extracellular matrix (ECM) is central to control of cell shape, mechanical responsiveness, motility and signalling, and hence to development, tissue formation, wound healing and th...
Surfaceome Profiling of Cell Lines and Patient-Derived Xenografts Confirm FGFR4, NCAM1, CD276, and Highlight AGRL2, JAM3, and L1CAM as Surface Targets for Rhabdomyosarcoma.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jan 30; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 30.
Abstract: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. The prognosis for patients with high-grade and metastatic disease is still very poor, and survivors are burdened with long-lasting side effects. Therefore, more effective and le...
LINC01146/F11R facilitates growth and metastasis of prostate cancer under the regulation of TGF-β.
Publication Type: Academic Journal
Source(s): The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2023 Jan; Vol. 225, pp. 106193. Date of Electronic Publication: 2022 Sep 23.
Abstract: The effect of long intergenic non-protein coding RNAs (lncRNAs) was verified in prostate cancer (PCa), but the mechanism of LINC01146 in PCa is unclear. Bioinformatics was applied to analyze LINC01146 expression in PCa and predict target genes of LINC0...
Quantitative analysis of the roles of IRM cell adhesion molecules in column formation in the fly brain.
Publication Type: Academic Journal
Source(s): Development, growth & differentiation [Dev Growth Differ] 2023 Jan; Vol. 65 (1), pp. 37-47. Date of Electronic Publication: 2022 Dec 28.
Abstract: The Drosophila visual center shows columnar structures, basic structural and functional units of the brain, that are shared with the mammalian cerebral cortex. Visual information received in the ommatidia in the compound eye is transmitted to the colum...
Programming multicellular assembly with synthetic cell adhesion molecules.
Publication Type: Academic Journal
Source(s): Nature [Nature] 2023 Feb; Vol. 614 (7946), pp. 144-152. Date of Electronic Publication: 2022 Dec 12.
Abstract: Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell-cell interactions in processes as diverse as tissue development, immune cell trafficking and the wiring of the nervous system 1-4 . Here we show that a wide arra...
Ihog proteins contribute to integrin-mediated focal adhesions.
Publication Type: Academic Journal
Source(s): Science China. Life sciences [Sci China Life Sci] 2023 Feb; Vol. 66 (2), pp. 366-375. Date of Electronic Publication: 2022 Sep 08.
Abstract: Integrin expression forms focal adhesions, but how this process is physiologically regulated is unclear. Ihog proteins are evolutionarily conserved, playing roles in Hedgehog signaling and serving as trans-homophilic adhesion molecules to mediate cell-...
Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM-1.
Publication Type: Academic Journal
Source(s): EMBO reports [EMBO Rep] 2023 Jan 09; Vol. 24 (1), pp. e55483. Date of Electronic Publication: 2022 Nov 16.
Abstract: Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration "hotspot" regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endothelial...