Advanced Search Results For "ALCOHOLIC cardiomyopathy"
Your filters
Myocardial Injury Caused by Chronic Alcohol Exposure-A Pilot Study Based on Proteomics.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2022 Jul 03; Vol. 27 (13). Date of Electronic Publication: 2022 Jul 03.
Abstract: Chronic alcohol exposure can cause myocardial degenerative diseases, manifested as cardiac insufficiency, arrhythmia, etc. These are defined as alcoholic cardiomyopathy (ACM). Alcohol-mediated myocardial injury has previously been studied through metab...
Knockdown of lectin-like oxidized low-density lipoprotein-1 ameliorates alcoholic cardiomyopathy via inactivating the p38 mitogen-activated protein kinase pathway.
Publication Type: Academic Journal
Source(s): Bioengineered [Bioengineered] 2022 Apr; Vol. 13 (4), pp. 8926-8936.
Abstract: LOX-1 triggers myocardial fibrosis, but its roles and mechanisms in alcoholic cardiomyopathy and the involvement of the downstream signaling pathways had not been fully reported. We planned to explore how LOX-1 facilitated myocardial fibrosis in alcoho...
Ectopic accumulation of ceramide in cardiomyocytes modulates alcoholic cardiomyopathy via the TLR4-dependent pathway.
Publication Type: Academic Journal
Source(s): Alcoholism, clinical and experimental research [Alcohol Clin Exp Res] 2022 Jun; Vol. 46 (6), pp. 1011-1022. Date of Electronic Publication: 2022 Apr 11.
Abstract: Background and Aims: Excessive alcohol consumption predisposes drinkers to develop alcoholic cardiomyopathy. Although cardiomyocyte loss is the hallmark of cardiomyopathy, the underlying mechanism remains elusive. This study examined the potential mech...
Characterization of myocardial oxidative metabolism and myocardial external efficiency in high-risk alcohol cardiotoxicity and alcoholic cardiomyopathy via dynamic 11 C-Acetate positron emission tomography.
Publication Type: Academic Journal
Source(s): Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2022 Feb; Vol. 29 (1), pp. 278-288. Date of Electronic Publication: 2020 Jun 18.
Abstract: Introduction: The purpose of this study was to evaluate subjects with high-risk alcohol cardiotoxicity and patients with alcoholic cardiomyopathy (ACM) via dynamic 11 C-Acetate positron emission tomography (PET) imaging as a myocardial oxidative metabo...
Epigenetic modification in alcohol use disorder and alcoholic cardiomyopathy: From pathophysiology to therapeutic opportunities.
Publication Type: Academic Journal
Source(s): Metabolism: clinical and experimental [Metabolism] 2021 Dec; Vol. 125, pp. 154909. Date of Electronic Publication: 2021 Oct 08.
Abstract: Alcohol consumption prompts detrimental psychological, pathophysiological and health issues, representing one of the major causes of death worldwide. Alcohol use disorder (AUD), which is characterized by compulsive alcohol intake and loss of control ov...
FGF21: a promising therapeutic agent for alcoholic cardiomyopathy? † .
Publication Type: Academic Journal
Source(s): The Journal of pathology [J Pathol] 2021 Jul; Vol. 254 (3), pp. 213-215. Date of Electronic Publication: 2021 Mar 26.
Abstract: The metabolic regulator fibroblast growth factor 21 (FGF21) has been reported as a cardioprotective factor regulating cardiac remodeling in several cardiac diseases. In a recent issue of The Journal of Pathology, Ferrer-Curriu, Guitart-Mampel et al inv...
On the Mechanism of Cardioprotective Effect of Fabomotizole in Alcoholic Cardiomyopathy.
Publication Type: Academic Journal
Source(s): Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2021 May; Vol. 171 (1), pp. 41-44. Date of Electronic Publication: 2021 May 29.
Abstract: The molecular mechanisms underlying the cardioprotective effect of fabomotizole were studied using the translational rat model of alcoholic cardiomyopathy developed by us. It was shown that intraperitoneal administration of fabomotizole (15 mg/kg) for ...
Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy.
Publication Type: Academic Journal
Source(s): Indian heart journal [Indian Heart J] 2021 May-Jun; Vol. 73 (3), pp. 389-391. Date of Electronic Publication: 2021 Apr 02.
Abstract: This study aimed to evaluate the effect of thiamine supplementation on left ventricular (LV) systolic function in patients of alcoholic cardiomyopathy(ACM) presenting with acute heart failure(HF). 11 newly diagnosed patients were included. They were tr...
A Pilot Metabolomic Study on Myocardial Injury Caused by Chronic Alcohol Consumption-Alcoholic Cardiomyopathy.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2021 Apr 09; Vol. 26 (8). Date of Electronic Publication: 2021 Apr 09.
Abstract: Chronic alcohol consumption leads to myocardial injury, ventricle dilation, and cardiac dysfunction, which is defined as alcoholic cardiomyopathy (ACM). To explore the induced myocardial injury and underlying mechanism of ACM, the Liber-DeCarli liquid ...