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Advanced Search Results For "ANIONS"

1 - 10 of 80,399 results for
 "ANIONS"
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The synthesis of thermostable, strongly basic Anion-Exchange resins using Cross-Linked biguanide and its application in the extraction of Sodium copper chlorophyllin.

Publication Type: Academic Journal

Source(s): Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2022 Nov 15; Vol. 1211, pp. 123436. Date of Electronic Publication: 2022 Sep 10.

Abstract: Commercially available, strongly basic anion-exchange resins with quaternary ammonium groups have been widely used in the purification of natural plant extracts. However, under the condition of high temperature (greater than 60 °C), these resins could ...

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Tsh Induces Agrp1 Neuron Proliferation in Oatp1c1-Deficient Zebrafish.

Publication Type: Academic Journal

Source(s): The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Nov 02; Vol. 42 (44), pp. 8214-8224. Date of Electronic Publication: 2022 Sep 23.

Abstract: Thyroid hormones (THs), thyroxine (T4), and triiodothyronine (T3), regulate growth, metabolism, and neurodevelopment. THs secretion is controlled by the pituitary thyroid-stimulating hormone (TSH) and the hypothalamic-pituitary-thyroid (HPT) axis. The ...

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Impact of acute inflammation on Band 3 protein anion exchange capability in human erythrocytes.

Publication Type: Academic Journal

Source(s): Archives of physiology and biochemistry [Arch Physiol Biochem] 2022 Oct; Vol. 128 (5), pp. 1242-1248. Date of Electronic Publication: 2020 May 13.

Abstract: Objective: The impact of acute inflammation, revealed by C-reactive protein (CRP) plasma levels, has been studied on the erythrocytes anion exchanger Band 3 protein. Methods: Anion exchange capability through Band 3 protein, lipid peroxidation, -SH mem...

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[ 11 C]glyburide PET imaging for quantitative determination of the importance of Organic Anion-Transporting Polypeptide transporter function in the human liver and whole-body.

Publication Type: Academic Journal

Source(s): Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Dec; Vol. 156, pp. 113994. Date of Electronic Publication: 2022 Nov 09.

Abstract: Organic Anion-Transporting Polypeptides (OATPs) are known to control the liver uptake of many drugs. Non-hepatic expression of OATPs has been reported although functional importance for whole-body pharmacokinetics (WBPK) remains unknown. Glyburide is a...

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Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease.

Publication Type: Academic Journal

Source(s): Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Nov; Vol. 112 (5), pp. 1098-1107. Date of Electronic Publication: 2022 Aug 11.

Abstract: Plasma exposure of the endothelin receptor antagonist atrasentan varies between individuals and is associated with nephroprotective effects and the risk of heart failure. We examined the influence of genetic polymorphisms on atrasentan plasma exposure ...

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Structural insights into light-driven anion pumping in cyanobacteria.

Publication Type: Academic Journal

Source(s): Nature communications [Nat Commun] 2022 Oct 29; Vol. 13 (1), pp. 6460. Date of Electronic Publication: 2022 Oct 29.

Abstract: Transmembrane ion transport is a key process in living cells. Active transport of ions is carried out by various ion transporters including microbial rhodopsins (MRs). MRs perform diverse functions such as active and passive ion transport, photo-sensin...

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Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility.

Publication Type: Academic Journal

Source(s): Nature communications [Nat Commun] 2022 Oct 20; Vol. 13 (1), pp. 6208. Date of Electronic Publication: 2022 Oct 20.

Abstract: Outer hair cell elecromotility, driven by prestin, is essential for mammalian cochlear amplification. Here, we report the cryo-EM structures of thermostabilized prestin (Pres TS ), complexed with chloride, sulfate, or salicylate at 3.52-3.63 Å resoluti...

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Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.

Publication Type: Academic Journal

Source(s): Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2022 Oct; Vol. 46, pp. 100464. Date of Electronic Publication: 2022 May 10.

Abstract: Non-synonymous genetic variants of organic anion-transporting polypeptide (OATP) 1A2 with altered transport activity have been identified. Naringin and narirutin, which are found in grapefruit, and their aglycon naringenin inhibit OATP1A2. However, the...

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Blockade of Organic Anion Transport in Humans After Treatment With the Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine.

Publication Type: Academic Journal

Source(s): Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Sep; Vol. 112 (3), pp. 653-664. Date of Electronic Publication: 2022 May 22.

Abstract: Probenecid is used to treat gout and hyperuricemia as well as increase plasma levels of antiviral drugs and antibiotics. In vivo, probenecid mainly inhibits the renal SLC22 organic anion transporters OAT1 (SLC22A6), OAT3 (SLC22A8), and URAT1 (SLC22A12)...

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The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature.

Publication Type: Academic Journal

Source(s): Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2022 Jul-Aug; Vol. 18 (7-8), pp. 459-468. Date of Electronic Publication: 2022 Aug 30.

Abstract: Introduction: Members of the solute carrier family of organic anion transporting polypeptides are responsible for the cellular uptake of a broad range of endogenous compounds and xenobiotics in multiple tissues. In particular, the polymorphic transport...

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