Advanced Search Results For "BRAIN"
Your filters
Reorganized Hubs of Brain Functional Networks after Acute Mild Traumatic Brain Injury.
Publication Type: Academic Journal
Source(s): Journal of neurotrauma [J Neurotrauma] 2023 Jan; Vol. 40 (1-2), pp. 63-73. Date of Electronic Publication: 2022 Sep 20.
Abstract: Mild traumatic brain injury (mTBI)-associated damage to hub regions can lead to disrupted modular structures of functional brain networks and may result in widespread cognitive and behavioral deficits. The spatial layout of brain connections and module...
Cerebral Metabolic Dysfunction at the Acute Phase of Traumatic Brain Injury Correlates with Long-Term Tissue Loss.
Publication Type: Academic Journal
Source(s): Journal of neurotrauma [J Neurotrauma] 2023 Mar; Vol. 40 (5-6), pp. 472-481. Date of Electronic Publication: 2022 Nov 04.
Abstract: Following traumatic brain injury (TBI), cerebral metabolic dysfunction, characterized by an elevated cerebral microdialysis (CMD) lactate/pyruvate (LP) ratio, is associated with poor outcome. However, the exact pathophysiological mechanisms underlying ...
Aberrant brain functional hubs convergence in the acute severe traumatic brain injury patients with rapidly recovering.
Publication Type: Academic Journal
Source(s): Neuroradiology [Neuroradiology] 2023 Jan; Vol. 65 (1), pp. 145-155. Date of Electronic Publication: 2022 Sep 03.
Abstract: Purpose: We aimed to identify the aberrant functional hubs in patients with acute severe traumatic brain injury (sTBI) and investigate whether they could help inform prognosis.Methods: Twenty-eight sTBI patients and health controls underwent imaging sc...
Early DNase-I therapy delays secondary brain damage after traumatic brain injury in adult mice.
Publication Type: Academic Journal
Source(s): Scientific reports [Sci Rep] 2023 Mar 16; Vol. 13 (1), pp. 4348. Date of Electronic Publication: 2023 Mar 16.
Abstract: Traumatic brain injury (TBI) causes the release of danger-associated molecular patterns (DAMP) from damaged or dead cells, which contribute to secondary brain damage after TBI. Cell-free DNA (cfDNA) is a DAMP known to cause disruption of the blood-brai...
Traumatic Brain Injury: Intraoperative Management and Intensive Care Unit Multimodality Monitoring.
Publication Type: Academic Journal
Source(s): Anesthesiology clinics [Anesthesiol Clin] 2023 Mar; Vol. 41 (1), pp. 39-78.
Abstract: Traumatic brain injury is a devastating event associated with substantial morbidity. Pathophysiology involves the initial trauma, subsequent inflammatory response, and secondary insults, which worsen brain injury severity. Management entails cardiopulm...
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption.
Publication Type: Academic Journal
Source(s): Mitochondrion [Mitochondrion] 2023 Mar; Vol. 69, pp. 71-82. Date of Electronic Publication: 2023 Jan 26.
Abstract: Blood-brain barrier disruption plays an important role in central nervous system diseases. This review provides information on the role of mitochondrial oxidative stress in brain microvascular endothelial cells in cellular dysfunction, the disruption o...
Roles of Astrocytic Endothelin ET B Receptor in Traumatic Brain Injury.
Publication Type: Academic Journal
Source(s): Cells [Cells] 2023 Feb 24; Vol. 12 (5). Date of Electronic Publication: 2023 Feb 24.
Abstract: Traumatic brain injury (TBI) is an intracranial injury caused by accidents, falls, or sports. The production of endothelins (ETs) is increased in the injured brain. ET receptors are classified into distinct types, including ET A receptor (ET A -R) and ...
YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Feb 20; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 20.
Abstract: The brain-gut axis (BGA) is a significant bidirectional communication pathway between the brain and gut. Traumatic brain injury (TBI) induced neurotoxicity and neuroinflammation can affect gut functions through BGA. N 6 -methyladenosine (m 6 A), as the...
Effects of whole-brain radiation therapy on the blood-brain barrier in immunocompetent and immunocompromised mouse models.
Publication Type: Academic Journal
Source(s): Radiation oncology (London, England) [Radiat Oncol] 2023 Feb 03; Vol. 18 (1), pp. 22. Date of Electronic Publication: 2023 Feb 03.
Abstract: Background: Approximately 20% of all cancer patients will develop brain metastases in their lifespan. The standard of care for patients with multiple brain metastases is whole-brain radiation therapy, which disrupts the blood-brain barrier. Previous st...
Temporal Patterns in Brain Tissue and Systemic Oxygenation Associated with Mortality After Severe Traumatic Brain Injury in Children.
Publication Type: Academic Journal
Source(s): Neurocritical care [Neurocrit Care] 2023 Feb; Vol. 38 (1), pp. 71-84. Date of Electronic Publication: 2022 Sep 28.
Abstract: Background: Brain tissue hypoxia is an independent risk factor for unfavorable outcomes in traumatic brain injury (TBI); however, systemic hyperoxemia encountered in the prevention and/or response to brain tissue hypoxia may also impact risk of mortali...