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ROptimus: a parallel general-purpose adaptive optimization engine.
Publication Type: Academic Journal
Source(s): Bioinformatics (Oxford, England) [Bioinformatics] 2023 May 04; Vol. 39 (5).
Abstract: Motivation: Various computational biology calculations require a probabilistic optimization protocol to determine the parameters that capture the system at a desired state in the configurational space. Many existing methods excel at certain scenarios, ...
Knowledge of handling medical emergencies among general dental practitioners pan India: a cross-sectional survery
Publication Type: Academic Journal
Source(s): BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract: Abstract Background Medical emergency situations in dental clinics have been contemplated to be an issue in most of the countries by reason of dentist’s lack of knowledge and preparedness to attend emergency situations in dental offices. The aim of thi...
Does macro-level general trust influence second language communication?: targeting prefectural capitals
Publication Type: Academic Journal
Source(s): BMC Research Notes, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract: Abstract Objectives This study investigated the macro-level effects of general trust on second language willingness to communicate (WTC) among Japanese individuals residing in 20 prefectural capitals. Previous research has shown the impact of individua...
ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data
Publication Type: Academic Journal
Source(s): Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract: Abstract Clustering is a critical component of single-cell RNA sequencing (scRNA-seq) data analysis and can help reveal cell types and infer cell lineages. Despite considerable successes, there are few methods tailored to investigating cluster-specific...
The influence of the water-salt extract of the medicinal leech Hirudo verbana Carena, 1820 on the general course of embryogenesis in rats after intraperitoneal administration
Publication Type: Academic Journal
Source(s): Біологічні студії, Vol 17, Iss 2, Pp 85-94 (2023)
Abstract: Background. The increase in infectious and non-infectious diseases occurrence during pregnancy prompts scientists to search for substances that can fight these ailments. This especially applies to natural substances that have virtually no side effects....
Cryo-ET study from in vitro to in vivo revealed a general folding mode of chromatin with two-start helical architecture
Publication Type: Academic Journal
Source(s): Cell Reports, Vol 42, Iss 9, Pp 113134- (2023)
Abstract: Summary: The organization and dynamics of chromatin fiber play crucial roles in regulating DNA accessibility for gene expression. Here we combine cryoelectron tomography (cryo-ET), sub-volume averaging, and 3D segmentation to visualize the in vitro and...
The association between sarcopenia and incident chronic lung disease in the general population: A longitudinal study based on CHARLS data
Publication Type: Academic Journal
Source(s): Experimental Gerontology, Vol 180, Iss , Pp 112257- (2023)
Abstract: Background: Data regarding the association of sarcopenia with chronic lung disease (CLD) has led to inconclusive results. The main goal of this research was to investigate the association between sarcopenia and CLD in middle-aged and elderly individual...
Iron metabolism and peripheral eosinophil count do not correlate in the general population
Publication Type: Academic Journal
Source(s): Journal of Biological Research (2023)
Abstract: Iron is a primary component of the human body and exerts many functions, mainly concerning red cells and the immune system. In addition, there is evidence that iron-deficiency anemia is associated with allergic diseases. Type 2 inflammation characteriz...
Identification of miR-671-5p and Its Related Pathways as General Mechanisms of Both Form-Deprivation and Lens-Induced Myopia in Mice
Publication Type: Academic Journal
Source(s): Current Issues in Molecular Biology, Vol 45, Iss 132, Pp 2060-2072 (2023)
Abstract: Animal models have been indispensable in shaping the understanding of myopia mechanisms, with form-deprivation myopia (FDM) and lens-induced myopia (LIM) being the most utilized. Similar pathological outcomes suggest that these two models are under the...
SMaSH: a scalable, general marker gene identification framework for single-cell RNA-sequencing.
Publication Type: Academic Journal
Source(s): BMC bioinformatics [BMC Bioinformatics] 2022 Aug 08; Vol. 23 (1), pp. 328. Date of Electronic Publication: 2022 Aug 08.
Abstract: Background: Single-cell RNA-sequencing is revolutionising the study of cellular and tissue-wide heterogeneity in a large number of biological scenarios, from highly tissue-specific studies of disease to human-wide cell atlases. A central task in single...