Advanced Search Results For "C-reactive protein"
Your filters
Fueling the flames of colon cancer - does CRP play a direct pro-inflammatory role?
Publication Type: Academic Journal
Source(s): Frontiers in immunology [Front Immunol] 2023 Mar 17; Vol. 14, pp. 1170443. Date of Electronic Publication: 2023 Mar 17 (Print Publication: 2023).
Abstract: Background: Systemic inflammation, diagnostically ascribed by measuring serum levels of the acute phase reactant C-reactive protein (CRP), has consistently been correlated with poor outcomes across cancer types. CRP exists in two structurally and funct...
C-reactive protein - My perspective on its first half century, 1930-1982.
Publication Type: Academic Journal
Source(s): Frontiers in immunology [Front Immunol] 2023 Mar 02; Vol. 14, pp. 1150103. Date of Electronic Publication: 2023 Mar 02 (Print Publication: 2023).
Abstract: C-reactive protein (CRP) was discovered in 1930 in the sera of patients during the acute phase of pneumococcal pneumonia and was so named because it bound to the C-polysaccharide of the pneumococcal cell wall. During the next half century many question...
Association between the FABP2 Ala54Thr and CRP+1059C/G polymorphisms and small dense LDL level in patients with atherosclerosis: a case-control study.
Publication Type: Academic Journal
Source(s): Archives of physiology and biochemistry [Arch Physiol Biochem] 2023 Feb; Vol. 129 (1), pp. 246-252. Date of Electronic Publication: 2020 Sep 24.
Abstract: Background: The polymorphisms of fatty acid-binding protein 2 (FABP2) and C-reactive protein (CRP) might act as genetic risk factors for atherosclerosis. The study aimed to investigate the relationship between FABP2 Ala54Thr and CRP+1059C/G polymorphis...
C-reactive protein isoforms as prognostic markers of COVID-19 severity.
Publication Type: Academic Journal
Source(s): Frontiers in immunology [Front Immunol] 2023 Jan 18; Vol. 13, pp. 1105343. Date of Electronic Publication: 2023 Jan 18 (Print Publication: 2022).
Abstract: C-reactive protein (CRP), an active regulator of the innate immune system, has been related to COVID-19 severity. CRP is a dynamic protein undergoing conformational changes upon activation in inflammatory microenvironments between pentameric and monome...
Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women.
Publication Type: Academic Journal
Source(s): BMC endocrine disorders [BMC Endocr Disord] 2023 Jan 06; Vol. 23 (1), pp. 7. Date of Electronic Publication: 2023 Jan 06.
Abstract: Background: Animal model studies suggest that change in the members of the suppressor of the cytokine signaling (SOCS) family (mainly SOCS1 and SOCS3) is linked to the pathogenesis of obesity-related metabolic disorders. Moreover, epigenetic modificati...
Regulation of Conformational Changes in C-reactive Protein Alters its Bioactivity.
Publication Type: Academic Journal
Source(s): Cell biochemistry and biophysics [Cell Biochem Biophys] 2022 Dec; Vol. 80 (4), pp. 595-608. Date of Electronic Publication: 2022 Aug 23.
Abstract: The acute phase C-reactive protein (CRP) is mainly synthesized and secreted by the liver in a cytokine-mediated response to infection or inflammation and circulates as a pentamer (pCRP) in plasma. Recent studies indicate that CRP is not only a marker b...
Evaluation of a point-of-care benchtop analyzer for quantitative measurement of C-reactive protein in canine serum and plasma.
Publication Type: Academic Journal
Source(s): Veterinary clinical pathology [Vet Clin Pathol] 2022 Dec; Vol. 51 (4), pp. 511-523. Date of Electronic Publication: 2022 May 16.
Abstract: Background: Canine C-reactive protein (cCRP) is an acute-phase protein that increases dramatically with inflammation and has potential utility in monitoring disease progression and response to treatment. Rapid, automated point-of-care test (POCT) forma...
Soluble klotho as an effective biomarker to characterize inflammatory states.
Publication Type: Academic Journal
Source(s): Annals of medicine [Ann Med] 2022 Dec; Vol. 54 (1), pp. 1520-1529.
Abstract: Background & Aims: Soluble α-Klotho (s-Klotho) is a circulating protein with pleiotropic effects that mainly induce protective effects. Our study investigates the associations between s-Klotho and several established inflammatory biomarkers, with the a...
Cholesterol-binding sequence is a key regulatory motif of cellular folding and conformational activation for C-reactive protein.
Publication Type: Academic Journal
Source(s): Molecular immunology [Mol Immunol] 2022 Dec; Vol. 152, pp. 123-128. Date of Electronic Publication: 2022 Nov 02.
Abstract: Human, rat, and mouse C-reactive protein (CRP) possess distinct expression patterns, but have similar conformations and conserved in vivo functions. We have previously demonstrated that this level-function mismatch is delicately tuned by the hidden act...
Weight loss via a low-carbohydrate diet improved the intestinal permeability marker, zonulin, in prostate cancer patients.
Publication Type: Academic Journal
Source(s): Annals of medicine [Ann Med] 2022 Dec; Vol. 54 (1), pp. 1221-1225.
Abstract: Background: Accumulating evidence suggest that gut microbiota may impact urologic health including prostate cancer (PC), potentially via affecting intestinal permeability (IP). Studies have indicated that disrupted IP may be improved by healthy diets a...