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Advanced Search Results For "CANCER chemotherapy"

1 - 10 of 151,283 results for
 "CANCER chemotherapy"
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Neo‐adjuvant FOLFIRINOX in borderline resectable and locally advanced pancreatic adenocarcinoma.

Publication Type: Academic Journal

Source(s): Asia Pacific Journal of Clinical Oncology. Dec2022, Vol. 18 Issue 6, p735-742. 8p.

Abstract: Background: Surgery and systemic therapy provide the best option for long‐term cancer control in localized resectable pancreas cancer. The present study assessed the efficacy and safety of neoadjuvant treatment with FOLFIRINOX in patients with borderli...

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Taxane‐based versus platinum‐based chemotherapy in early recurrent gastric cancer after radical surgery with S‐1 adjuvant chemotherapy: A multi‐institutional retrospective analysis.

Publication Type: Academic Journal

Source(s): Asia Pacific Journal of Clinical Oncology. Dec2022, Vol. 18 Issue 6, p540-545. 6p.

Abstract: Aim: This study aimed to compare the efficacy of taxane‐based and platinum‐based regimens in patients with early recurrent gastric cancer after radical surgery with S‐1 adjuvant chemotherapy. Methods: The medical records of 118 patients from six instit...

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Efficacy and safety of FLOT regimen vs DCF, FOLFOX, and ECF regimens as perioperative chemotherapy treatments for resectable gastric cancer patients; a report from the middle east.

Publication Type: Academic Journal

Source(s): Journal of Research in Pharmaceutical Sciences. Dec2022, Vol. 17 Issue 6, p621-634. 14p.

Abstract: Background and purpose: This study aimed to compare the efficacy and toxicity of perioperative chemotherapy regimens including epirubicin, cisplatin, 5-fluorouracil (ECF), docetaxel, cisplatin, 5-fluorouracil (DCF), leucovorin, 5-fluorouracil, oxalipla...

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Total neoadjuvant therapy versus standard therapy in locally advanced rectal cancer: A systematic review and meta-analysis of 15 trials.

Publication Type: Academic Journal

Source(s): PLoS ONE. 11/4/2022, Vol. 17 Issue 11, p1-13. 13p.

Abstract: Background: Neoadjuvant chemoradiotherapy (nCRT) before total mesorectal excision (TME) and followed systemic chemotherapy is widely accepted as the standard therapy for locally advanced rectal cancer (LARC). This meta-analysis was to evaluate the curr...

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Nationwide trends and outcomes of neoadjuvant chemotherapy in pancreatic cancer – an analysis of the Swedish national pancreatic cancer registry.

Publication Type: Academic Journal

Source(s): Scandinavian Journal of Gastroenterology. Nov2022, Vol. 57 Issue 11, p1361-1366. 6p.

Abstract: During the last decade, neoadjuvant therapy (NAT) for pancreatic cancer has become more frequent. Pathological response and overall survival are promising; however, various post-operative complications have been reported. Our primary aim was to compare...

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Neoadjuvant versus adjuvant chemotherapy in bladder cancer: a nationwide cohort study.

Publication Type: Academic Journal

Source(s): Journal of Cancer Research & Clinical Oncology. Nov2022, Vol. 148 Issue 11, p3135-3144. 10p.

Abstract: Purpose: Radical cystectomy is the standard of care for muscle-invasive bladder cancer. However, the 5-year survival rate is only about 50%. Therefore, additional treatments are needed. We compared the perioperative outcomes, overall survival, and trea...

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Ferroptosis molecular inducers: A future direction for malignant tumor chemotherapy.

Publication Type: Academic Journal

Source(s): Biocell. 2022, Vol. 46 Issue 7, p1599-1611. 13p.

Abstract: Iron-dependent ferroptosis is a form of cell death dependent on iron levels. Cells that undergo ferroptosis have glutathione (GSH) deficiency, reduced Glutathione peroxidase-4 (GPX4) activity and intracellular lipid peroxidation, Mitochondria, lysosome...

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PCDH7 knockdown potentiates colon cancer cells to chemotherapy via inducing ferroptosis and changes in autophagy through restraining MEK1/2/ERK/c-Fos axis.

Publication Type: Academic Journal

Source(s): Biochemistry & Cell Biology. 2022, Vol. 100 Issue 6, p445-457. 13p.

Abstract: La chimiothérapie est une stratégie de traitement couramment utilisée dans le cancer du côlon, une tumeur maligne répandue. Cette étude a pour but de sonder la fonction et le mécanisme d'action de la protocadhérine 7 (PCDH7) dans le cancer du côlon. De...

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Dual role of quercetin in enhancing the efficacy of cisplatin in chemotherapy and protection against its side effects: a review.

Publication Type: Academic Journal

Source(s): Archives of Physiology & Biochemistry. Dec2022, Vol. 128 Issue 6, p1438-1452. 15p.

Abstract: Chemotherapy has opened a new window in cancer therapy. However, the resistance of cancer cells has dramatically reduced the efficacy of chemotherapy. Cisplatin is a chemotherapeutic agent and its potential in cancer therapy has been restricted by resi...

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Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer.

Publication Type: Academic Journal

Source(s): International Journal of Biological Macromolecules. Dec2022:Part A, Vol. 222, p562-572. 11p.

Abstract: Chemotherapy resistance is one of the most critical challenges in colorectal cancer (CRC) treatment. The occurrence and development of chemotherapy resistance closely related to the tumor immune microenvironment (TIME). As the most important immunosupp...

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