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Advanced Search Results For "CELL lines"

1 - 10 of 925,756 results for
 "CELL lines"
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Cell line authentication: a necessity for reproducible biomedical research.

Publication Type: Academic Journal

Source(s): The EMBO journal [EMBO J] 2022 Jul 18; Vol. 41 (14), pp. e111307. Date of Electronic Publication: 2022 Jun 27.

Abstract: Immortalized or continuous cell lines are invaluable tools in basic and preclinical research. However, the widespread use of misidentified cell lines is a serious threat to scientific reproducibility. Based on the experiences of mandatory cell line aut...

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Establishment and characterization of NCC-GCTB5-C1: a novel cell line of giant cell tumor of bone.

Publication Type: Academic Journal

Source(s): Human cell [Hum Cell] 2022 Sep; Vol. 35 (5), pp. 1621-1629. Date of Electronic Publication: 2022 Jun 02.

Abstract: Giant cell tumor of bone (GCTB), is a rare intermediate malignant bone tumor with high local infiltrative ability, and is genetically characterized by mutation in the H3-3A gene. Standard treatment is curative surgical tumor resection. GCTB demonstrate...

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Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.

Publication Type: Academic Journal

Source(s): The Prostate [Prostate] 2022 Apr; Vol. 82 (5), pp. 584-597. Date of Electronic Publication: 2022 Jan 27.

Abstract: Background: Primary and metastatic prostate cancers have low mutation rates and recurrent alterations in a small set of genes, enabling targeted sequencing of prostate cancer-associated genes as an efficient approach to characterizing patient samples (...

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Establishment of an immortalized human erythroid cell line sustaining differentiation potential without inducible gene expression system.

Publication Type: Academic Journal

Source(s): Human cell [Hum Cell] 2022 Jan; Vol. 35 (1), pp. 408-417. Date of Electronic Publication: 2021 Nov 24.

Abstract: Ex vivo manufactured red blood cells (RBC) generated from immortalized erythroid cell lines which can continuously grow are expected to become a significant alternative in future transfusion therapies. The ectopic expression of human papilloma virus (H...

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Short tandem repeat profiling for the authentication of cancer stem-like cells.

Publication Type: Academic Journal

Source(s): International journal of cancer [Int J Cancer] 2021 Mar 15; Vol. 148 (6), pp. 1489-1498. Date of Electronic Publication: 2020 Nov 09.

Abstract: Colorectal and glioblastoma cancer stem-like cells (CSCs) are essential for translational research. Cell line authentication by short tandem repeat (STR) profiling ensures reproducibility of results in oncology research. This technique enables to ident...

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FOXN3 Expression Regulated by miR-299-5p Inhibiting the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells.

Publication Type: Academic Journal

Source(s): Protein and peptide letters [Protein Pept Lett] 2022; Vol. 29 (9), pp. 788-795.

Abstract: Background: Oral squamous cell carcinoma (OSCC) is one of the commonest malignancies of the oral cavity. FOXN3 is a tumor suppressor that represses the progression of many tumors. Nonetheless, its role in OSCC has not been elucidated. This work is perf...

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Gold Nanorods are Selective Cytotoxic Agents.

Publication Type: Academic Journal

Source(s): Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2022; Vol. 22 (5), pp. 991-998.

Abstract: Background: Gold nanorods (GNRs) are very promising agents with multiple applications in medicine and biology. However, the cytotoxic effects of GNRs have not been fully explored.Objective: Therefore, the main objective of this study was to determine t...

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Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma.

Publication Type: Academic Journal

Source(s): Disease models & mechanisms [Dis Model Mech] 2022 Jan 01; Vol. 15 (1). Date of Electronic Publication: 2022 Jan 31.

Abstract: There is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, i.e. UN-SCC679 and UN-SCC680, ...

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Development of the CK-MB-1 trastuzumab-resistant HER2-positive breast cancer cell line and xenograft animal models.

Publication Type: Academic Journal

Source(s): Cancer medicine [Cancer Med] 2021 Apr; Vol. 10 (7), pp. 2370-2379. Date of Electronic Publication: 2021 Mar 05.

Abstract: Background: Patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer who fail to respond to anti-HER2 treatments have poor prognoses. Most trastuzumab-resistant breast cancer cell lines available from biobanks feature either...

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Adaptation and characterization of Anatid herpesvirus 1 in different permissible cell lines.

Publication Type: Academic Journal

Source(s): Biologicals : journal of the International Association of Biological Standardization [Biologicals] 2021 Apr; Vol. 70, pp. 1-6. Date of Electronic Publication: 2021 Mar 18.

Authors:

Abstract: Duck viral enteritis is an acute, contagious infection of Anatidae family members. The disease is caused by Anatid herpesvirus 1 (AnHV-1). The infection of AnHV-1 is controlled by vaccination to the flock with chick embryo adapted attenuated vaccine in...

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