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Advanced Search Results For "CELLULAR therapy"

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 "CELLULAR therapy"
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The Autologous Hematopoietic Stem Cells Transplantation Combination-Based Chimeric Antigen Receptor T-Cell Therapy Improves Outcomes of Relapsed/Refractory Central Nervous System B-Cell Lymphoma.

Publication Type: Academic Journal

Source(s): Journal of Oncology. 11/29/2022, Vol. 2022, p1-20. 20p.

Abstract: Objective. The objective is to explore the effectiveness and safety of CAR T-cell therapy in advanced relapsed/refractory central nervous system B-cell lymphoma and compare the impact of autologous stem cell transplantation (ASCT) plus CAR T-cell thera...

Soluble and Immobilized Anti-CD3/28 Distinctively Expand and Differentiate Primary Human T Cells: An Implication for Adoptive T Cell Therapy.

Publication Type: Academic Journal

Source(s): Iranian Journal of Allergy, Asthma & Immunology. Dec2022, Vol. 21 Issue 6, p630-637. 8p.

Abstract: Cell-based cancer therapies have led to a paradigm shift in the treatment of patients with various cancers. To date, a vast majority of cancer immunotherapies have used genetically engineered T cells to target tumors. Stimulation and ex vivo expansion ...

Characterization of three-dimensional multipotent adipose-derived stem cell spheroids.

Publication Type: Academic Journal

Source(s): Biocell. 2022, Vol. 46 Issue 7, p1705-1716. 12p.

Abstract: Human adipose stem cells (hADSCs) are reliable sources for cell therapy. However, the clinical applications are limited by the decrease in activity during in vitro culture. We used a knockout serum replacement (KSR) medium, Eppendorf (EP) tube culture,...

Mesenchymal Stem Cells for Perianal Crohn's Disease.

Publication Type: Academic Journal

Source(s): Turkish Journal of Colorectal Disease. Sep2022, Vol. 32 Issue 3, p161-169. 9p.

Abstract: Unfortunately, perianal fistulizing Crohn's disease (CD) is notoriously difficult to cure. The ulceration and inflammation in CD which leads to fistulizing disease is the likely reason fistulas are notoriously difficult to treat. Most studies which eva...

Umbilical Cord Mesenchymal Stem Cells Ameliorate Premature Ovarian Insufficiency in Rats.

Publication Type: Academic Journal

Source(s): Evidence-based Complementary & Alternative Medicine (eCAM). 5/30/2022, p1-12. 12p. 7 Graphs, 1 Map.

Abstract: Premature ovarian insufficiency (POI) or premature ovarian failure (POF) is known as a state of hypergonadotropic hypogonadism. Stem cell therapy is expected to be used in the treatment of POI. The aim of the present study was to explore the feasibilit...

Effects of CIK Cell Therapy Combined with Camrelizumab on the Quality of Life in Patients with Nasopharyngeal Carcinoma and Analysis of Prognostic Factors.

Publication Type: Academic Journal

Source(s): Computational Intelligence & Neuroscience. 5/9/2022, p1-8. 8p.

Abstract: Objective. To investigate the effects of CIK (cytokine-induced killer) cell therapy combined with camrelizumab on the quality of life in patients with nasopharyngeal carcinoma and prognostic factors. Methods. In this retrospective study, the materials ...

Alloreactivity of Allogeneic Mesenchymal Stem/Stromal Cells and Other Cellular Therapies: A Concise Review.

Publication Type: Academic Journal

Source(s): Stem Cells International. 3/9/2022, p1-8. 8p.

Abstract: Cellular therapies, deemed live medicine, have brought a wave of new generation biological therapies to treat previously untreatable diseases such as cancers and degenerative diseases like osteoarthritis. These cellular therapies have gained significan...

Applications of covariate adjusted nonparametric methods to CCTRN clinical trials.

Publication Type: Academic Journal

Source(s): Communications in Statistics: Case Studies & Data Analysis. 2022, Vol. 8 Issue 4, p728-737. 10p.

Abstract: CCTRN is a Cardiovascular Cell Therapy Research Network. There were three randomized double blinded controlled stem cell clinical trials conducted in its first phase. The main results of these three clinical trials were published with conventional para...

Mesenchymal stem cells derived secretome as an innovative cell-free therapeutic approach.

Publication Type: Academic Journal

Source(s): Biocell. 2022, Vol. 46 Issue 3, p907-911. 5p.

Abstract: The paracrine and immunomodulatory cytokines secreted by mesenchymal stem cells (MSCs), generally referred to as the MSCs derived secretome, has substantial potential for the treatment of many chronic and degenerative diseases. MSCs secretome contains ...

Exosome engineering in cell therapy and drug delivery.

Publication Type: Academic Journal

Source(s): Inflammopharmacology. Feb2023, Vol. 31 Issue 1, p145-169. 25p.

Abstract: Cell-derived exosomes have opened new horizons in modern therapy for advanced drug delivery and therapeutic applications, due to their key features such as low immunogenicity, high physicochemical stability, capacity to penetrate into tissues, and the ...