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Advanced Search Results For "CORONAVIRUSES"

1 - 10 of 128,401 results for
 "CORONAVIRUSES"
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Coronaviruses exploit a host cysteine-aspartic protease for replication.

Publication Type: Academic Journal

Source(s): Nature [Nature] 2022 Sep; Vol. 609 (7928), pp. 785-792. Date of Electronic Publication: 2022 Aug 03.

Authors:

Abstract: Highly pathogenic coronaviruses, including severe acute respiratory syndrome coronavirus 2 (refs.  1,2 ) (SARS-CoV-2), Middle East respiratory syndrome coronavirus 3 (MERS-CoV) and SARS-CoV-1 (ref.  4 ), vary in their transmissibility and pathogenicity...

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Recent Emergence of Bovine Coronavirus Variants with Mutations in the Hemagglutinin-Esterase Receptor Binding Domain in U.S. Cattle.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Sep 27; Vol. 14 (10). Date of Electronic Publication: 2022 Sep 27.

Abstract: Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. The balance of the opposing activities of the surface spike (S) and hemagglutinin-esterase (HE) glycoproteins contro...

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Immunoinformatics Identification of the Conserved and Cross-Reactive T-Cell Epitopes of SARS-CoV-2 with Human Common Cold Coronaviruses, SARS-CoV, MERS-CoV and Live Attenuated Vaccines Presented by HLA Alleles of Indonesian Population.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Oct 24; Vol. 14 (11). Date of Electronic Publication: 2022 Oct 24.

Abstract: Reports on T-cell cross-reactivity against SARS-CoV-2 epitopes in unexposed individuals have been linked with prior exposure to the human common cold coronaviruses (HCCCs). Several studies suggested that cross-reactive T-cells response to live attenuat...

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Human coronaviruses: Origin, host and receptor.

Publication Type: Academic Journal

Source(s): Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [J Clin Virol] 2022 Oct; Vol. 155, pp. 105246. Date of Electronic Publication: 2022 Jul 21.

Authors:

Abstract: Coronavirus is a type of RNA-positive single-stranded virus with an envelope, and the spines on its surface derived its official name. Seven human coronaviruses 229E, OC43, SARS, NL63, HKU1, MERS, SARS-CoV-2 can cause both a mild cold and an epidemic o...

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Pan-coronavirus epitope buried in spike.

Publication Type: Academic Journal

Source(s): Nature reviews. Microbiology [Nat Rev Microbiol] 2022 Sep; Vol. 20 (9), pp. 510.

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Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus strains circulating in China from 2020 to 2021.

Publication Type: Academic Journal

Source(s): BMC veterinary research [BMC Vet Res] 2022 Nov 08; Vol. 18 (1), pp. 392. Date of Electronic Publication: 2022 Nov 08.

Authors:

Abstract: Background: Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, has become the major causative agent of acute gastroenteritis in piglets since 2010 in China.Results: In the current study, 91 complete spike (S) gene sequences were obtained f...

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A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo.

Publication Type: Academic Journal

Source(s): Cell reports. Medicine [Cell Rep Med] 2022 Oct 18; Vol. 3 (10), pp. 100774. Date of Electronic Publication: 2022 Sep 29.

Authors:

Abstract: "Pan-coronavirus" antivirals targeting conserved viral components can be designed. Here, we show that the rationally engineered H84T-banana lectin (H84T-BanLec), which specifically recognizes high mannose found on viral proteins but seldom on healthy h...

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Human seasonal coronavirus neutralization and COVID-19 severity.

Publication Type: Academic Journal

Source(s): Journal of medical virology [J Med Virol] 2022 Oct; Vol. 94 (10), pp. 4820-4829. Date of Electronic Publication: 2022 Jul 18.

Abstract: The virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the global coronavirus disease-2019 (COVID-19) pandemic, spread rapidly around the world causing high morbidity and mortality. However, there are four known, endemi...

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Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Sep 18; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 18.

Authors:

Abstract: The ongoing spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused hundreds of millions of cases and millions of victims worldwide with serious consequences to global health and economies. Although many vaccines protecting ag...

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Binding and neutralizing abilities of antibodies towards SARS-CoV-2 S2 domain.

Publication Type: Academic Journal

Source(s): Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2022 Nov 30; Vol. 18 (5), pp. 2055373. Date of Electronic Publication: 2022 Apr 13.

Authors:

Abstract: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants have been reported to be resistant to several neutralizing antibodies (NAbs) targeting Receptor Binding Domain (RBD) and N Terminal Domain (NTD) of spike (S) protein and thus inducin...

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