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Advanced Search Results For "Carcinoma genetics"

1 - 10 of 154,510 results for
 "Carcinoma genetics"
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Genetics and genomics in healthcare: the future is now.

Publication Type: Academic Journal

Source(s): Singapore Medical Journal. Jan2023, Vol. 64 Issue 1, p4-6. 3p.

Abstract: An introduction is presented in which author discusses articles on topics including focuses on paradigm that progressed over the past decade is how to view and manage hereditary disorders, with heritable cancer leading the way.

Gene Mutation and Its Association with Clinicopathological Features in Young Patients with Non-Small-Cell Lung Cancer.

Publication Type: Academic Journal

Source(s): Emergency Medicine International. 7/5/2022, p1-6. 6p.

Abstract: Background. We investigated the correlation between genetic mutations and clinical-pathological features in young patients with NSCLC. Methods. Clinicopathologic information of 102 young NSCLC patients was collected. Direct ctDNA sequencing of a portio...

The Role of American Thyroid Association Pediatric Thyroid Cancer Risk Stratification and BRAFV600E Mutation in Predicting the Response to Treatment in Papillary Thyroid Cancer Patients ≤18 Years Old.

Publication Type: Academic Journal

Source(s): Journal of Clinical Research in Pediatric Endocrinology. Jun2022, Vol. 14 Issue 2, p196-206. 11p.

Abstract: Objective: This study aimed to evaluate the role of risk stratification by the American Thyroid Association (ATA) pediatric thyroid cancer risk levels and BRAFV600E mutation to predict the response to treatment in papillary thyroid cancer (PTC) patient...

Overexpression of miRNA-93-5p Promotes Proliferation and Migration of Bladder Urothelial Carcinoma via Inhibition of KLF9.

Publication Type: Academic Journal

Source(s): Computational & Mathematical Methods in Medicine. 4/21/2022, p1-12. 12p.

Abstract: We focused on studying the effects of a key miRNA-mRNA axis in bladder urothelial carcinoma (BUC). Firstly, miRNAs and mRNAs differentially expressed in BUC were analyzed. Clinical information in the TCGA database was used for survival analysis, and th...

miR-1251-5p Overexpression Inhibits Proliferation, Migration, and Immune Escape in Clear Cell Renal Cell Carcinoma by Targeting NPTX2.

Publication Type: Academic Journal

Source(s): Journal of Oncology. 3/10/2022, p1-9. 9p.

Abstract: Background. miR-1251-5p was identified as a tumor suppressor in a variety of malignancies; however, its biological function in clear cell renal cell carcinoma (ccRCC) is unknown. Methods. The Cancer Genome Atlas (TCGA) database was used to download exp...

Loss of EphA7 Expression in Basal Cell Carcinoma by Hypermethylation of CpG Islands in the Promoter Region.

Publication Type: Academic Journal

Source(s): Analytical Cellular Pathology: Cellular Oncology. 1/22/2022, p1-7. 7p.

Abstract: Basal cell carcinoma (BCC) is the most common malignancy worldwide, with increasing incidence. BCCs present low mortality but high morbidity, and its pathogenesis remains unclear. Eph receptors have been implicated in tumorigenesis. EphA7 plays a role ...

Solitary extramedullary plasmacytoma of the left main bronchus: A case report and literature review.

Publication Type: Academic Journal

Source(s): Thoracic Cancer. Feb2023, Vol. 14 Issue 4, p419-422. 4p.

Abstract: Tracheal tumors are rare, accounting for 0.1% of all malignancies. Squamous cell carcinoma and adenoid cystic carcinoma are the two most prevalent tracheal cancers. Less than 20 cases of extramedullary plasmacytoma in the trachea and main bronchus have...

Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis.

Publication Type: Academic Journal

Source(s): Journal of Hepatology. Mar2023, Vol. 78 Issue 3, p584-595. 12p.

Abstract: Identifying individuals at higher risk of developing hepatocellular carcinoma (HCC) is pivotal to improve the performance of surveillance strategies. Herein, we aimed to evaluate the ability of single nucleotide polymorphisms (SNPs) to refine HCC risk ...

Optimized Detection of Unknown MET Exon 14 Skipping Mutations in Routine Testing for Patients With Non–Small-Cell Lung Cancer.

Publication Type: Academic Journal

Source(s): JCO Precision Oncology. 2/27/2023, Vol. 7, p1-9. 9p.

Abstract: PURPOSE: MET exon 14 (MET ex14) skipping is an actionable biomarker in non–small-cell lung cancer. However, MET variants are highly complex and diverse, and not all variants lead to exon 14 skipping. Assessing the skipping effect of unknown variants is...

Cost Savings of Expedited Care with Upfront Next-Generation Sequencing Testing versus Single-Gene Testing among Patients with Metastatic Non-Small Cell Lung Cancer Based on Current Canadian Practices.

Publication Type: Academic Journal

Source(s): Current Oncology. Feb2023, Vol. 30 Issue 2, p2348-2365. 18p. 4 Charts, 3 Graphs.

Abstract: This study assessed the total costs of testing, including the estimated costs of delaying care, associated with next-generation sequencing (NGS) versus single-gene testing strategies among patients with newly diagnosed metastatic non-small cell lung ca...

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