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Controlling lipid crystallization across multiple length scales by directed shear flow.
Publication Type: Academic Journal
Source(s): Journal of colloid and interface science [J Colloid Interface Sci] 2023 Jan 15; Vol. 630 (Pt A), pp. 731-741. Date of Electronic Publication: 2022 Oct 06.
Abstract: The crystallization behavior of lipids is relevant in many fields such as adipose tissue formation and regeneration, forensic investigations and food production. Using a lipid model system composed of triacylglycerols, we study the formation of crystal...
Shaping droplet by semiflexible micro crystallizer for high quality crystal harvest.
Publication Type: Academic Journal
Source(s): Journal of colloid and interface science [J Colloid Interface Sci] 2023 Jan; Vol. 629 (Pt A), pp. 334-345. Date of Electronic Publication: 2022 Aug 28.
Abstract: Droplet crystallization behavior held great potential in crystal preparation, micromaterial engineering, and molecular assembly. However, restricted by natural surface tension, the intrinsic crystallization regulation and efficient harvest of high qual...
Chiral Amplification through the Interplay of Racemizing Conditions and Asymmetric Crystal Growth.
Publication Type: Academic Journal
Source(s): Journal of the American Chemical Society [J Am Chem Soc] 2023 Jan 11; Vol. 145 (1), pp. 436-442. Date of Electronic Publication: 2022 Dec 19.
Abstract: Amplification of enantiomeric excesses (ee) is routinely observed during chiral crystallization of conglomerate crystals for which the enantiomers undergo racemization in solution. Although routes comprising a combination of crystal growth and dissolut...
Controlling polymorphism in molecular cocrystals by variable temperature ball milling.
Publication Type: Academic Journal
Source(s): Faraday discussions [Faraday Discuss] 2023 Jan 05; Vol. 241 (0), pp. 178-193. Date of Electronic Publication: 2023 Jan 05.
Abstract: Mechanochemistry offers a unique opportunity to modify and manipulate crystal forms, often providing new products as compared with conventional solution methods. While promising, there is little known about how to control the solid form through mechano...
Regulation of orientation birefringence for cellulose acetate film: The role of crystallization and orientation.
Publication Type: Academic Journal
Source(s): Carbohydrate polymers [Carbohydr Polym] 2022 Nov 15; Vol. 296, pp. 119915. Date of Electronic Publication: 2022 Jul 25.
Abstract: Cellulose acetate (CA) based films are widely used in liquid crystal displays due to their outstanding transparency, and a certain orientation birefringence of CA films is required when they are used as retardation films. The regulation of orientation ...
Process intensification of atorvastatin calcium crystallization for target polymorph development via continuous combined cooling and antisolvent crystallization using an oscillatory baffled crystallizer.
Publication Type: Academic Journal
Source(s): International journal of pharmaceutics [Int J Pharm] 2022 Nov 05; Vol. 627, pp. 122172. Date of Electronic Publication: 2022 Sep 07.
Abstract: In this paper, continuous crystallization of Atorvastatin calcium (ASC) using a continuous oscillatory baffled crystallizer (COBC) has been investigated. Like most API manufacturing, ASC is manufactured batchwise and the pure API is recovered via batch...
Designing Glass and Crystalline Phases of Metal-Bis(acetamide) Networks to Promote High Optical Contrast.
Publication Type: Academic Journal
Source(s): Journal of the American Chemical Society [J Am Chem Soc] 2022 Dec 07; Vol. 144 (48), pp. 22262-22271. Date of Electronic Publication: 2022 Nov 28.
Abstract: Owing to their high tunability and predictable structures, metal-organic materials offer a powerful platform to study glass formation and crystallization processes and to design glasses with unique properties. Here, we report a novel series of glass-fo...
Discovered two polymorphs and two solvates of lamotrigine-tolfenamic acid salt: Thermal behavior and crystal morphological differences.
Publication Type: Academic Journal
Source(s): International journal of pharmaceutics [Int J Pharm] 2022 Nov 25; Vol. 628, pp. 122310. Date of Electronic Publication: 2022 Oct 18.
Abstract: Multi-component pharmaceutical systems such as cocrystal and salt have gained popularity in academia and industry due to their ability to regulate the poor physicochemical properties of active pharmaceutical ingredients (APIs). However, different cryst...
Recent Advances on the Biological Study of Pharmaceutical Cocrystals.
Publication Type: Academic Journal
Source(s): AAPS PharmSciTech [AAPS PharmSciTech] 2022 Nov 17; Vol. 23 (8), pp. 303. Date of Electronic Publication: 2022 Nov 17.
Abstract: As a low-risk, low-cost, but high-reward route, cocrystallization of drugs with appropriate coformers is applied to improve the physiochemical and biopharmaceutical properties of drugs. Currently, most researchers concentrate their efforts on the prepa...
Ligancy effects on nucleation kinetics.
Publication Type: Academic Journal
Source(s): The Journal of chemical physics [J Chem Phys] 2022 Nov 07; Vol. 157 (17), pp. 174111.
Abstract: Nucleation of particles into crystalline structures can be observed in a wide range of systems from metallic and metal-organic compounds to colloidal and polymeric patch particles. Here, we perform kinetic Monte Carlo simulations to study the nucleatio...