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Advanced Search Results For "DELTAS"

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 "DELTAS"
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Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus.

Publication Type: Academic Journal

Source(s): Virology journal [Virol J] 2022 Oct 17; Vol. 19 (1), pp. 163. Date of Electronic Publication: 2022 Oct 17.

Abstract: Background: Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated with the most severe form of hepatitis and progressive chronic liver disease and cirrhosis. Chronic hepatitis D, ...

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N 6 -Methyladenine Modification of Hepatitis Delta Virus Regulates Its Virion Assembly by Recruiting YTHDF1.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Oct 12; Vol. 96 (19), pp. e0112422. Date of Electronic Publication: 2022 Sep 14.

Abstract: Hepatitis delta virus (HDV) is a defective satellite virus that uses hepatitis B virus (HBV) envelope proteins to form its virions and infect hepatocytes via the HBV receptors. Concomitant HDV/HBV infection continues to be a major health problem, with ...

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C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration.

Publication Type: Academic Journal

Source(s): Cells [Cells] 2022 Oct 22; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 22.

Abstract: Pancreatic Ductal Adenocarcinoma (PDAC) is among the most aggressive human cancers and occurs globally at an increasing incidence. Metastases are the primary cause of cancer-related death and, in the majority of cases, PDAC is accompanied by metastatic...

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Memory and naïve gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy.

Publication Type: Academic Journal

Source(s): Clinical immunology (Orlando, Fla.) [Clin Immunol] 2021 Sep; Vol. 230, pp. 108820. Date of Electronic Publication: 2021 Aug 06.

Abstract: Background: Peanut oral immunotherapy (POIT) has provided desensitization to peanut allergic individuals. Limited immunological evaluation exists during the first 24-weeks of POIT.Objective: Regulatory T-cells (Tregs) are antigen induced immunosuppress...

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Bulevirtide 2mg-based real-life treatment of hepatitis Delta with genotypes 1 and 5 viruses at more than 20 months of follow-up.

Publication Type: Editorial & Opinion

Source(s): Clinics and research in hepatology and gastroenterology [Clin Res Hepatol Gastroenterol] 2022 Dec; Vol. 46 (10), pp. 102035. Date of Electronic Publication: 2022 Oct 20.

Abstract: Competing Interests: Declaration of interests P.B. and R.G received funding from Gilead Sciences. C.D. and P.C. have no conflicts of interest to declare. Funding sources had no role in the design and conduct of the study; collection, management, analys...

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Novel concepts on mechanisms underlying Hepatitis Delta virus persistence and related pathogenesis.

Publication Type: Academic Journal

Source(s): Journal of viral hepatitis [J Viral Hepat] 2022 Dec; Vol. 29 (12), pp. 1038-1047. Date of Electronic Publication: 2022 Oct 18.

Abstract: Hepatitis Delta virus is the smallest known human virus, exploiting the HBV surface proteins (HBsAg) for the release of its progeny and de novo entry into hepatocytes. Ever growing evidence have highlighted the existence of multiple mechanisms underlyi...

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Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells.

Publication Type: Academic Journal

Source(s): Archives of biochemistry and biophysics [Arch Biochem Biophys] 2022 Nov 30; Vol. 731, pp. 109428. Date of Electronic Publication: 2022 Oct 10.

Abstract: Cannabidiolic acid (CBDA) can activate peroxisome proliferator-activated receptor-α (PPARα) and PPARγ. Whether CBDA can activate PPARβ/δ has not been examined sufficiently to date. Since previous studies showed that triple-negative breast cancer cells ...

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Direct regulation of TCR rearrangement and expression by E proteins during early T cell development.

Publication Type: Academic Journal

Source(s): WIREs mechanisms of disease [WIREs Mech Dis] 2022 Nov; Vol. 14 (6), pp. e1578. Date of Electronic Publication: 2022 Jul 18.

Abstract: γδ T cells are widely distributed throughout mucosal and epithelial cell-rich tissues and are an important early source of IL-17 in response to several pathogens. Like αβ T cells, γδ T cells undergo a stepwise process of development in the thymus that ...

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Brazil Nut Supplementation Does Not Regulate PPARβ/δ Signaling Pathway in Peripheral Blood Mononuclear Cells from Coronary Artery Disease Patients.

Publication Type: Academic Journal

Source(s): Journal of the American Nutrition Association [J Am Nutr Assoc] 2022 Nov-Dec; Vol. 41 (8), pp. 780-787. Date of Electronic Publication: 2021 Sep 13.

Abstract: Background: Peroxisome proliferator-activated receptor (PPAR)β/δ activation is a potential target for modulation of inflammation in cardiovascular disease. PPARβ/δ activation depends on the presence of a ligand, which may be pharmacological or natural,...

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Grape seed extract supplementation modulates hepatic lipid metabolism in rats. Implication of PPARβ/δ.

Publication Type: Academic Journal

Source(s): Food & function [Food Funct] 2022 Oct 31; Vol. 13 (21), pp. 11353-11368. Date of Electronic Publication: 2022 Oct 31.

Abstract: In mammals, the liver is involved in nutrient metabolism and in the regulation of lipid and glucose homeostasis. Multiple studies have described improvements in liver disorders after regular consumption of grape seed extract (GSE). GSE prevents or amel...

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