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    • Anticarcinogenic Potency of EF24: An Overview of Its Pharmacokinetics, Efficacy, Mechanism of Action, and Nanoformulation for Drug Delivery.

    Publication Type: Academic Journal

    Source(s): Cancers. Nov2023, Vol. 15 Issue 22, p5478. 31p.

    Abstract: Simple Summary: This study summarizes the current state of knowledge about the anticancer potential of the curcumin analog EF24, including its pharmacokinetic profile, therapeutic efficacy, underlying mechanisms, and advancements in nanoformulations fo...

    Changing Trends in B-Cell Non-Hodgkin Lymphoma Treatment: The Role of Novel Monoclonal Antibodies in Clinical Practice.

    Publication Type: Academic Journal

    Source(s): Cancers. Nov2023, Vol. 15 Issue 22, p5397. 21p.

    Abstract: Simple Summary: We are entering an exciting new phase in the history of non-Hodgkin lymphoma treatment. Advances in monoclonal antibody-based therapies, which began with rituximab in the 1990s but have only recently started to show their full potential...

    A Comparison of the Antitumor Efficacy of Novel Multi-Specific Tribodies with Combinations of Approved Immunomodulatory Antibodies.

    Publication Type: Academic Journal

    Source(s): Cancers. Nov2023, Vol. 15 Issue 22, p5345. 18p.

    Abstract: Simple Summary: One of the main challenges faced by cancer immunotherapy is the emergence of resistance against monotherapies, mediated by several immune escape mechanisms, which are able to impair therapy outcomes. Here, we investigated the biological...

    Bridging the Gap: Exploring the Preclinical Potential of Pereskia grandifolia in Metabolic-Associated Fatty Liver Disease.

    Publication Type: Academic Journal

    Source(s): Evidence-based Complementary & Alternative Medicine (eCAM). 11/9/2023, p1-14. 14p.

    Abstract: Metabolic-associated fatty liver disease (MAFLD) is a complex condition characterized by steatosis and metabolic disturbances. Risk factors such as diabetes, cigarette smoking, and dyslipidaemia contribute to its development and progression. Effective ...

    A Real-World Safety Analysis of Upadacitinib Based on FDA Adverse Event Reporting System (FAERS).

    Publication Type: Academic Journal

    Source(s): Journal of Clinical Pharmacy & Therapeutics. 11/2/2023, p1-13. 13p.

    Abstract: Objectives. To investigate adverse events (AEs) associated with upadacitinib in the real world using data mining from the FDA Adverse Event Reporting System (FAERS). Methods. Disproportionality analysis, including the reporting odds ratio (ROR), the pr...

    A Phase II Study of S-1 plus Oxaliplatin for Patients with Recurrent Non-Squamous Cell Carcinoma of the Uterine Cervix (Tohoku Gynecologic Cancer Unit: TGCU206 Study).

    Publication Type: Academic Journal

    Source(s): Cancers. Nov2023, Vol. 15 Issue 21, p5201. 9p.

    Abstract: Simple Summary: Cervical cancer is the fourth most common cancer in the world and the fourth leading cause of cancer death in women. In 2020, there were 604,000 new cases and 342,000 deaths from cervical cancer worldwide. Among these, non-squamous cell...

    Complications of Intrathecal Baclofen Pump Therapy: An Institutional Experience from Saudi Arabia.

    Publication Type: Academic Journal

    Source(s): Healthcare (2227-9032). Nov2023, Vol. 11 Issue 21, p2820. 16p.

    Abstract: The intrathecal baclofen pump (ITB) is one of the advanced treatment options in the management of spasticity. This retrospective cohort study was conducted to identify the complications of ITB treatment at a tertiary care rehabilitation facility. Vario...

    A Phase II Study of Osimertinib in Patients with Advanced-Stage Non-Small Cell Lung Cancer following Prior Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) Therapy with EGFR and T790M Mutations Detected in Plasma Circulating Tumour DNA (PLASMA Study)

    Publication Type: Academic Journal

    Source(s): Cancers. Oct2023, Vol. 15 Issue 20, p4999. 16p.

    Abstract: Simple Summary: Lung cancers with EGFR gene mutations treated with targeted therapy often develop another genetic change (T790M) that allows them to be treated with a further targeted therapy, Osimertinib, with good outcomes. The gold standard for the ...

    Development of a Single-Neurosphere Culture to Assess Radiation Toxicity and Pre-Clinical Cancer Combination Therapy Safety.

    Publication Type: Academic Journal

    Source(s): Cancers. Oct2023, Vol. 15 Issue 20, p4916. 17p.

    Abstract: Simple Summary: Exposure to radiation during nuclear catastrophes, natural sources such as space travel, or during cancer treatment can lead to central nervous system toxicity. The high sensitivity of neural progenitor cells (NPCs) to radiation poses a...

    Efficacy, Safety and Economic Evaluation of Wolbigachul-Tang for Chronic Cough Due to Upper Airway Cough Syndrome (UACS): A Study Protocol for Randomized, Double-Blind, Active-Comparator Controlled, Parallel, Exploratory Clinical Trial.

    Publication Type: Academic Journal

    Source(s): Healthcare (2227-9032). Oct2023, Vol. 11 Issue 20, p2733. 13p.

    Abstract: Upper airway cough syndrome (UACS) is a common cause of chronic cough characterized by upper airway symptoms, including nasal discharge and throat discomfort. Empirical treatments for UASC-induced chronic cough, such as first-generation antihistamines,...

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