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Advanced Search Results For "DYNAMICS"

1 - 10 of 862,587 results for
 "DYNAMICS"
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Stability of a class of nonlinear hierarchical size-structured population model.

Publication Type:Academic Journal

Source(s):Mathematical biosciences and engineering : MBE [Math Biosci Eng] 2022 Jul 19; Vol. 19 (10), pp. 10143-10159.

Abstract:This paper investigates the existence of positive equilibrium as well as the stability of positive equilibrium and zero equilibrium in a nonlinear size-structured hierarchical population model. Under the condition that larger individuals are more compe...

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A nonlinear population dynamics model of patient diagnosis and treatment involving in two level medical institutions and its qualitative analysis of positive singularity.

Publication Type:Academic Journal

Source(s):Mathematical biosciences and engineering : MBE [Math Biosci Eng] 2022 Jan 07; Vol. 19 (3), pp. 2575-2591.

Abstract:In this article, we firstly establish a nonlinear population dynamical model to describe the changes and interaction of the density of patient population of China's primary medical institutions (PHCIs) and hospitals in China's medical system. Next we g...

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Exploring Mechanisms of Allosteric Regulation and Communication Switching in the Multiprotein Regulatory Complexes of the Hsp90 Chaperone with Cochaperones and Client Proteins: Atomistic Insights from Integrative Biophysical Modeling and Network Analysis of Conformational Landscapes.

Publication Type:Academic Journal

Source(s):Journal of molecular biology [J Mol Biol] 2022 Sep 15; Vol. 434 (17), pp. 167506. Date of Electronic Publication: 2022 Feb 21.

Abstract:Understanding molecular principles underlying Hsp90 chaperone functions and modulation of client activity is fundamental to dissect activation mechanisms of many proteins. In this work, we performed a computational investigation of the Hsp90-Hsp70-Hop-...

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Regulation of mitochondrial fusion and mitophagy by intra-tumoral delivery of membrane-fused mitochondria or Midiv-1 enhances sensitivity to doxorubicin in triple-negative breast cancer.

Publication Type:Academic Journal

Source(s):Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Sep; Vol. 153, pp. 113484. Date of Electronic Publication: 2022 Aug 02.

Abstract:Increasing mitochondrial fusion by intra-tumoral grafting of membrane-fused mitochondria created with Pep-1 conjugation (P-Mito) contributes to breast cancer treatment, but it needs to be validated. Using mitochondrial division inhibitor-1 (Mdivi-1, Md...

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Prediction of self-diffusion coefficients of chemically diverse pure liquids by all-atom molecular dynamics simulations.

Publication Type:Academic Journal

Source(s):Journal of computational chemistry [J Comput Chem] 2022 Oct 30; Vol. 43 (28), pp. 1892-1900. Date of Electronic Publication: 2022 Aug 09.

Abstract:Molecular self-diffusion coefficients underlie various kinetic properties of the liquids involved in chemistry, physics, and pharmaceutics. In this study, 547 self-diffusion coefficients are calculated based on all-atom molecular dynamics (MD) simulati...

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Brownian dynamics simulations of shear-induced aggregation of charged colloidal particles in the presence of hydrodynamic interactions.

Publication Type:Academic Journal

Source(s):Journal of colloid and interface science [J Colloid Interface Sci] 2022 Oct 15; Vol. 624, pp. 637-649. Date of Electronic Publication: 2022 May 13.

Abstract:Hypothesis: In spite of the abundant literature on Brownian simulations of the aggregation behavior of colloidal suspensions both under quiescent conditions and in the presence of shear, few works performed simulations including the effect of hydrodyna...

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Mitochondria oxidative stress mediated nicotine-promoted activation of pancreatic stellate cells by regulating mitochondrial dynamics.

Publication Type:Academic Journal

Source(s):Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2022 Oct; Vol. 84, pp. 105436. Date of Electronic Publication: 2022 Jul 14.

Abstract:Nicotine, one of the main ingredients of cigarettes, promotes activation of pancreatic stellate cells(PSCs) and exacerbates pancreatic fibrosis in previous studies. Here we focus on the inner relationship between mitochondrial oxidative stress and mito...

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Novel optimal trajectory tracking for nonlinear affine systems with an advanced critic learning structure.

Publication Type:Academic Journal

Source(s):Neural networks : the official journal of the International Neural Network Society [Neural Netw] 2022 Oct; Vol. 154, pp. 131-140. Date of Electronic Publication: 2022 Jul 16.

Abstract:In this paper, a critic learning structure based on the novel utility function is developed to solve the optimal tracking control problem with the discount factor of affine nonlinear systems. The utility function is defined as the quadratic form of the...

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Tamoxifen modulates mitochondrial dynamics through AMPK and MAPK during nutrition deprivation.

Publication Type:Academic Journal

Source(s):Cell biology international [Cell Biol Int] 2022 Oct; Vol. 46 (10), pp. 1661-1671. Date of Electronic Publication: 2022 Jul 12.

Abstract:The interaction of cancer cells with their tumor microenvironment determines key events in the progression of the disease, therapeutic efficacy, and the development of drug resistance. Here, we presented evidence that tamoxifen support breast cancer gr...

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Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.

Publication Type:Academic Journal

Source(s):Journal of applied toxicology : JAT [J Appl Toxicol] 2022 Oct; Vol. 42 (10), pp. 1618-1627. Date of Electronic Publication: 2022 May 22.

Abstract:There is in vivo and in vitro evidence that exposure to benzene or its metabolites could affect the mitochondrial function. However, the underlying molecular mechanism of mitochondrial damage remains to be elucidated. In this study, exposure of human p...

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