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A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.
Publication Type: Academic Journal
Source(s): American journal of veterinary research [Am J Vet Res] 2022 Oct 03; Vol. 83 (11), pp. 1-8. Date of Electronic Publication: 2022 Oct 03.
Abstract: Objective: To identify genetic associations with primary glaucoma (PG) in American Cocker Spaniels using a genome-wide association study (GWAS).Animals: A nationwide ambidirectional case-control cohort study was performed in American Cocker Spaniels th...
Ehrlichia canis: Molecular characterization and genetic diversity based on the p28 and trp36 genes.
Publication Type: Academic Journal
Source(s): Research in veterinary science [Res Vet Sci] 2023 Feb; Vol. 155, pp. 88-102. Date of Electronic Publication: 2022 Dec 13.
Abstract: Ehrlichia canis is a common tick-borne intracellular pathogen causing canine monocytic ehrlichiosis (CME) in dogs worldwide. The aims of this study were to investigate the genetic diversity and antigenicity of E. canis based on the p28 and trp36 genes ...
Haplotypes of Dirofilaria repens from Poland and selected countries of Central, North-Eastern Europe and the Middle East: An evaluation on the relation between the genetic diversity and the geographic distribution of the fast-spreading parasite.
Publication Type: Academic Journal
Source(s): Veterinary parasitology [Vet Parasitol] 2023 Mar; Vol. 315, pp. 109882. Date of Electronic Publication: 2023 Jan 20.
Abstract: Subcutaneous dirofilariosis is a fast-spreading infection of dogs, and occasionally of other carnivores and humans. Several factors contribute to its spread, including climate change, which facilitates development and survival of Dirofilaria repens in ...
Prevalence and genetic diversity of canine coronavirus in northeastern China during 2019-2021.
Publication Type: Academic Journal
Source(s): Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2023 Mar; Vol. 94, pp. 101956. Date of Electronic Publication: 2023 Feb 14.
Abstract: Canine coronavirus (CCoV) is associated with diarrhea in dogs, with a high incidence and sometimes even death. However, there is currently limited information about its prevalence and molecular characterization in northeastern China. Therefore, in this...
Animal models of Alzheimer's disease: Applications, evaluation, and perspectives.
Publication Type: Academic Journal
Source(s): Zoological research [Zool Res] 2022 Nov 18; Vol. 43 (6), pp. 1026-1040.
Abstract: Although great advances in elucidating the molecular basis and pathogenesis of Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches have been developed, AD remains an incurable disease. Evidence shows that AD neuropatho...
High genetic diversity of Babesia canis (Piana & Galli-Valerio, 1895) in a recent local outbreak in Berlin/ Brandenburg, Germany.
Publication Type: Academic Journal
Source(s): Transboundary and emerging diseases [Transbound Emerg Dis] 2022 Sep; Vol. 69 (5), pp. e3336-e3345. Date of Electronic Publication: 2022 Jun 25.
Abstract: Canine babesiosis caused by Babesia canis (Piana & Galli-Valerio, 1895) is emerging in new regions in Europe since its vector Dermacentor reticulatus (Fabricius, 1794) is expanding its geographic range. In the Berlin/Brandenburg area in northeast Germa...
Canine and feline P-glycoprotein deficiency: What we know and where we need to go.
Publication Type: Academic Journal
Source(s): Journal of veterinary pharmacology and therapeutics [J Vet Pharmacol Ther] 2023 Jan; Vol. 46 (1), pp. 1-16. Date of Electronic Publication: 2022 Nov 03.
Abstract: In 2001 the molecular genetic basis of so-called "ivermectin sensitivity" in herding breed dogs was determined to be a P-glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called "the MDR1 mutation." We have learned a gr...
Dog ownership in infancy is protective for persistent wheeze in 17q21 asthma-risk carriers.
Publication Type: Academic Journal
Source(s): The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Feb; Vol. 151 (2), pp. 423-430. Date of Electronic Publication: 2022 Oct 20.
Abstract: Background: Asthma-associated single nucleotide polymorphisms from large genome-wide association studies only explain a fraction of genetic heritability. Likely causes of the missing heritability include broad phenotype definitions and gene-environment...
Inflammatory phenotype, clinicopathologic variables, and effects of long-term methylene blue in dogs with hereditary methemoglobinemia caused by cytochrome b5 reductase deficiency.
Publication Type: Academic Journal
Source(s): American journal of veterinary research [Am J Vet Res] 2023 Jan 19; Vol. 84 (2). Date of Electronic Publication: 2023 Jan 19.
Abstract: Objective: To determine whether dogs with cytochrome b5 reductase (CYB5R) deficiency have a constitutive proinflammatory phenotype, characterize hematologic and serum chemistry results, and describe changes in methemoglobin (MetHb) levels and serum C-r...
Synergistic HA and NS mutations enhanced the virulence of a mouse-adapted H1N1 influenza A virus.
Publication Type: Academic Journal
Source(s): Veterinary microbiology [Vet Microbiol] 2023 Jan; Vol. 276, pp. 109615. Date of Electronic Publication: 2022 Dec 05.
Abstract: H1N1 reassortants between the swine Eurasian avian-like (EA) and H1N1 2009 pandemic (H1N1 pdm/09) viruses have been circulating stably in pig populations for more than ten years, and they may have contributed to increased human infections. Whether thes...