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Ehrlichia canis: Molecular characterization and genetic diversity based on the p28 and trp36 genes.
Publication Type: Academic Journal
Source(s): Research in veterinary science [Res Vet Sci] 2023 Feb; Vol. 155, pp. 88-102. Date of Electronic Publication: 2022 Dec 13.
Abstract: Ehrlichia canis is a common tick-borne intracellular pathogen causing canine monocytic ehrlichiosis (CME) in dogs worldwide. The aims of this study were to investigate the genetic diversity and antigenicity of E. canis based on the p28 and trp36 genes ...
Haplotypes of Dirofilaria repens from Poland and selected countries of Central, North-Eastern Europe and the Middle East: An evaluation on the relation between the genetic diversity and the geographic distribution of the fast-spreading parasite.
Publication Type: Academic Journal
Source(s): Veterinary parasitology [Vet Parasitol] 2023 Mar; Vol. 315, pp. 109882. Date of Electronic Publication: 2023 Jan 20.
Abstract: Subcutaneous dirofilariosis is a fast-spreading infection of dogs, and occasionally of other carnivores and humans. Several factors contribute to its spread, including climate change, which facilitates development and survival of Dirofilaria repens in ...
Prevalence and genetic diversity of canine coronavirus in northeastern China during 2019-2021.
Publication Type: Academic Journal
Source(s): Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2023 Mar; Vol. 94, pp. 101956. Date of Electronic Publication: 2023 Feb 14.
Abstract: Canine coronavirus (CCoV) is associated with diarrhea in dogs, with a high incidence and sometimes even death. However, there is currently limited information about its prevalence and molecular characterization in northeastern China. Therefore, in this...
Establishment of a reverse genetics system for rabies virus strain Komatsugawa.
Publication Type: Academic Journal
Source(s): The Journal of veterinary medical science [J Vet Med Sci] 2022 Nov 07; Vol. 84 (11), pp. 1508-1513. Date of Electronic Publication: 2022 Sep 29.
Abstract: The rabies virus strain Komatsugawa isolated from a dog in Tokyo in the 1940s retains biological properties as a field strain, providing an effective model for studying rabies pathogenesis. To facilitate molecular studies on the pathogenesis, this stud...
A genome-wide association study to investigate genetic loci associated with primary glaucoma in American Cocker Spaniels.
Publication Type: Academic Journal
Source(s): American journal of veterinary research [Am J Vet Res] 2022 Oct 03; Vol. 83 (11), pp. 1-8. Date of Electronic Publication: 2022 Oct 03.
Abstract: Objective: To identify genetic associations with primary glaucoma (PG) in American Cocker Spaniels using a genome-wide association study (GWAS).Animals: A nationwide ambidirectional case-control cohort study was performed in American Cocker Spaniels th...
SCN9A variant in a family of mixed breed dogs with congenital insensitivity to pain.
Publication Type: Academic Journal
Source(s): Journal of veterinary internal medicine [J Vet Intern Med] 2023 Jan; Vol. 37 (1), pp. 230-235. Date of Electronic Publication: 2023 Jan 11.
Abstract: Background: Congenital insensitivity to pain (CIP) and hereditary sensory and autonomic neuropathies (HSANs) are a rare group of genetic disorders causing inability to feel pain. Three different associated variants have been identified in dogs: 1 in Bo...
Serum levels and genetic variations of cytokines in two canine breeds (Ibizan hound and boxer) in the Mediterranean region, in terms of Leishmania infantum infection.
Publication Type: Academic Journal
Source(s): Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2022 Nov-Dec; Vol. 90-91, pp. 101908. Date of Electronic Publication: 2022 Nov 14.
Abstract: Leishmaniosis, endemic to the Mediterranean area and considered to be the most important zoonosis in Europe, is caused by Leishmania infantum, an intracellular protozoan parasite transmitted by sandflies Phlebotomus. On the one hand, the Ibizan hound, ...
Interleukin 6 and interferon gamma haplotypes are related to cytokine serum levels in dogs in an endemic Leishmania infantum region.
Publication Type: Academic Journal
Source(s): Infectious diseases of poverty [Infect Dis Poverty] 2023 Feb 10; Vol. 12 (1), pp. 9. Date of Electronic Publication: 2023 Feb 10.
Abstract: Background: The Ibizan Hound is a canine breed native to the Mediterranean region, where leishmaniasis is an endemic zoonosis. Several studies indicate a low prevalence of this disease in Ibizan Hound dogs, whereas other canine breeds present a high pr...
Inflammatory phenotype, clinicopathologic variables, and effects of long-term methylene blue in dogs with hereditary methemoglobinemia caused by cytochrome b5 reductase deficiency.
Publication Type: Academic Journal
Source(s): American journal of veterinary research [Am J Vet Res] 2023 Jan 19; Vol. 84 (2). Date of Electronic Publication: 2023 Jan 19.
Abstract: Objective: To determine whether dogs with cytochrome b5 reductase (CYB5R) deficiency have a constitutive proinflammatory phenotype, characterize hematologic and serum chemistry results, and describe changes in methemoglobin (MetHb) levels and serum C-r...
Canine and feline P-glycoprotein deficiency: What we know and where we need to go.
Publication Type: Academic Journal
Source(s): Journal of veterinary pharmacology and therapeutics [J Vet Pharmacol Ther] 2023 Jan; Vol. 46 (1), pp. 1-16. Date of Electronic Publication: 2022 Nov 03.
Abstract: In 2001 the molecular genetic basis of so-called "ivermectin sensitivity" in herding breed dogs was determined to be a P-glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called "the MDR1 mutation." We have learned a gr...