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Advanced Search Results For "EBOLA virus disease"

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Novel Antiviral Molecules against Ebola Virus Infection.

Publication Type: Academic Journal

Source(s): International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 19, p14791. 17p.

Abstract: Infection with Ebola virus (EBOV) is responsible for hemorrhagic fever in humans with a high mortality rate. Combined efforts of prevention and therapeutic intervention are required to tackle highly variable RNA viruses, whose infections often lead to ...

Effect of Interferon Gamma on Ebola Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line.

Publication Type: Academic Journal

Source(s): Viruses (1999-4915). Oct2023, Vol. 15 Issue 10, p2077. 17p.

Abstract: Ebola virus disease (EVD) represents a global health threat. The etiological agents of EVD are six species of Orthoebolaviruses, with Orthoebolavirus zairense (EBOV) having the greatest public health and medical significance. EVD pathogenesis occurs as...

Adipose Tissues from Human and Bat-Derived Cell Lines Support Ebola Virus Infection.

Publication Type: Academic Journal

Source(s): Viruses (1999-4915). Sep2023, Vol. 15 Issue 9, p1827. 11p.

Abstract: Ebola virus is a zoonotic pathogen with a geographic range covering diverse ecosystems that are home to many potential reservoir species. Although researchers have detected Ebola virus RNA and serological evidence of previous infection in different rod...

The Effect of Previous Exposure to Malaria Infection and Clinical Malaria Episodes on the Immune Response to the Two-Dose Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccine Regimen.

Publication Type: Academic Journal

Source(s): Vaccines. Aug2023, Vol. 11 Issue 8, p1317. 14p.

Abstract: We assessed whether the immunogenicity of the two-dose Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen with a 56-day interval between doses was affected by exposure to malaria before dose 1 vaccination and by clinical episodes of malaria in the period im...

The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection.

Publication Type: Academic Journal

Source(s): Viruses (1999-4915). Jul2023, Vol. 15 Issue 7, p1590. 11p.

Abstract: Ebola virus (EBOV) causes Ebola virus disease (EVD), which is characterized by hemorrhagic fever with high mortality rates in humans. EBOV sexual transmission has been a concern since the 2014–2016 outbreak in Africa, as persistent infection in the tes...

Cheminformatics-Based Study Identifies Potential Ebola VP40 Inhibitors.

Publication Type: Academic Journal

Source(s): International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 7, p6298. 34p.

Abstract: The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in primates. However, there are no regulatorily approved drugs against the Ebola virus disease (EVD). The highly virulent and lethal nature of EVD highlights the nee...

COVID-19 Vaccine Perceptions among Ebola-Affected Communities in North Kivu, Democratic Republic of the Congo, 2021.

Publication Type: Academic Journal

Source(s): Vaccines. May2023, Vol. 11 Issue 5, p973. 18p.

Abstract: Populations affected by humanitarian crises and emerging infectious disease outbreaks may have unique concerns and experiences that influence their perceptions toward vaccines. In March 2021, we conducted a survey to examine the perceptions toward COVI...

Preventive Measures against Ebola and COVID-19 and Their Impact on Human Dirty-Hand Disease Mitigation in Côte d'Ivoire.

Publication Type: Academic Journal

Source(s): Sustainability (2071-1050). Apr2023, Vol. 15 Issue 8, p6810. 14p.

Abstract: Hygiene is the most useful public health measure for preventing infections of important endemic and emerging diseases of global significance. This study aimed to assess the impact of these public health preventive measures on dirty hand diseases. A ret...

The potential epidemic threat of Ebola virus and the development of a preventive vaccine.

Publication Type: Academic Journal

Source(s): Journal of Biosafety & Biosecurity. Jun2023, Vol. 5 Issue 2, p67-78. 12p.

Abstract: Ebola virus (EBOV) is classified as a category A pathogen as it causes viral hemorrhagic fever, one of the most-deadly virus-related diseases. Since its discovery in 1976, EBOV has caused a number of global public health incidents, which have posed a s...

A retrospective cohort investigation of seroprevalence of Marburg virus and ebolaviruses in two different ecological zones in Uganda.

Publication Type: Academic Journal

Source(s): BMC infectious diseases [BMC Infect Dis] 2020 Jul 01; Vol. 20 (1), pp. 461. Date of Electronic Publication: 2020 Jul 01.

Abstract: Background: Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining com...

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