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Advanced Search Results For "ESTROGEN"

1 - 10 of 199,830 results for
 "ESTROGEN"
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Estrogen Receptor Signaling in the Immune System.

Publication Type: Academic Journal

Source(s): Endocrine reviews [Endocr Rev] 2023 Jan 12; Vol. 44 (1), pp. 117-141.

Abstract: The immune system functions in a sexually dimorphic manner, with females exhibiting more robust immune responses than males. However, how female sex hormones affect immune function in normal homeostasis and in autoimmunity is poorly understood. In this...

ERα/ERβ-directed CBS transcription mediates E2β-stimulated hUAEC H2S production.

Publication Type: Academic Journal

Source(s): Journal of molecular endocrinology [J Mol Endocrinol] 2023 Jan 09; Vol. 70 (2). Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2023).

Abstract: Elevated endogenous estrogens stimulate human uterine artery endothelial cell (hUAEC) hydrogen sulfide (H2S) production by selectively upregulating the expression of H2S synthesizing enzyme cystathionine β-synthase (CBS), but the underlying mechanisms ...

Comprehensive analysis of cellular estrogen signaling in representative estrogen receptor ligands.

Publication Type: Academic Journal

Source(s): Chemico-biological interactions [Chem Biol Interact] 2023 Jan 05; Vol. 369, pp. 110303. Date of Electronic Publication: 2022 Dec 10.

Authors:

Abstract: The estrogen receptor (ER)-mediated signaling pathway in physiological and biochemical aspects is very important in the environment, including food. The physiological action of estrogen is mediated by ER alpha (ERα) and beta (ERβ), whose physiological ...

Human cell-based estrogen receptor beta dimerization assay.

Publication Type: Academic Journal

Source(s): Chemico-biological interactions [Chem Biol Interact] 2023 Jan 05; Vol. 369, pp. 110264. Date of Electronic Publication: 2022 Nov 17.

Authors:

Abstract: Estrogen is not only responsible for important functions in the human body, such as cell growth, reproduction, differentiation, and development, but it is also deeply related to pathological processes, such as cancer, metabolic and cardiovascular disea...

Sex and age differences in the distribution of estrogen receptors in mice.

Publication Type: Academic Journal

Source(s): Neuroscience letters [Neurosci Lett] 2023 Jan 10; Vol. 793, pp. 136973. Date of Electronic Publication: 2022 Nov 19.

Abstract: Estrogen receptors (ERα and ERβ) are crucial for the regulation of socio-sexual behaviors and the organization of sex-specific neural networks in the developing brain. However, how the distribution patterns of ERα and ERβ change throughout life is uncl...

The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens.

Publication Type: Academic Journal

Source(s): The Journal of biological chemistry [J Biol Chem] 2023 Jan; Vol. 299 (1), pp. 102757. Date of Electronic Publication: 2022 Nov 30.

Abstract: Antiestrogens (AEs) are used to treat all stages of estrogen receptor (ER)-positive breast cancer. Selective estrogen receptor modulators such as tamoxifen have tissue-specific partial agonist activity, while selective estrogen receptor downregulators ...

The hormonal environment and estrogen receptor signaling alters Chlamydia muridarum infection in vivo .

Publication Type: Academic Journal

Source(s): Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Dec 27; Vol. 12, pp. 939944. Date of Electronic Publication: 2022 Dec 27 (Print Publication: 2022).

Abstract: Genital Chlamydia is the most common bacterial sexually transmitted infection in the United States and worldwide. Previous studies indicate that the progression of chlamydial infection is influenced by various factors, including the female sex hormones...

Membrane Estrogen Receptor β Is Sufficient to Mitigate Cardiac Cell Pathology.

Publication Type: Academic Journal

Source(s): Endocrinology [Endocrinology] 2022 Dec 19; Vol. 164 (2).

Abstract: Estrogen acting through estrogen receptor β (ERβ) has been shown to oppose the stimulation of cardiac myocytes and cardiac fibroblasts that results in cardiac hypertrophy and fibrosis. Previous work has implicated signal transduction from ERβ as being ...

Extracellular Acidosis Differentially Regulates Estrogen Receptor β-Dependent EMT Reprogramming in Female and Male Melanoma Cells.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 Dec 06; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 06.

Abstract: Clinical outcomes of melanoma patients pointed out a gender disparity that supports a correlation between sex hormone activity on estrogen receptors (ER) and melanoma development and progression. Here, we found that the epithelial-to-mesenchymal transi...

BRAFV600E Mutation Enhances Estrogen-Induced Metastatic Potential of Thyroid Cancer by Regulating the Expression of Estrogen Receptors.

Publication Type: Academic Journal

Source(s): Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2022 Dec; Vol. 37 (6), pp. 879-890. Date of Electronic Publication: 2022 Dec 26.

Authors:

Abstract: Backgruound: Cross-talk between mitogen-activated protein kinase and estrogen has been reported; however, the role of BRAFV600E in the estrogen responsiveness of thyroid cancer is unknown. We elucidated the effect of BRAFV600E on the estrogen-induced i...

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