Advanced Search Results For "Endoplasmic Reticulum Stress genetics"
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RASSF1 is identified by transcriptome coordination analysis as a target of ATF4.
Publication Type: Academic Journal
Source(s): FEBS open bio [FEBS Open Bio] 2023 Mar; Vol. 13 (3), pp. 556-569. Date of Electronic Publication: 2023 Feb 14.
Abstract: Evaluation of gene co-regulation is a powerful approach for revealing regulatory associations between genes and predicting biological function, especially in genetically diverse samples. Here, we applied this strategy to identify transcripts that are c...
Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jan 19; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 19.
Abstract: For the past several years, fundamental research on Sigma-1R (S1R) protein has unveiled its necessity for maintaining proper cellular homeostasis through modulation of calcium and lipid exchange between the endoplasmic reticulum (ER) and mitochondria, ...
Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response.
Publication Type: Academic Journal
Source(s): The Journal of biological chemistry [J Biol Chem] 2023 Feb; Vol. 299 (2), pp. 102836. Date of Electronic Publication: 2022 Dec 23.
Abstract: Gap junctional intercellular communication (GJIC) involving astrocytes is important for proper CNS homeostasis. As determined in our previous studies, trafficking of the predominant astrocyte GJ protein, Connexin43 (Cx43), is disrupted in response to i...
Polystyrene nanoplastics aggravates lipopolysaccharide-induced apoptosis in mouse kidney cells by regulating IRE1/XBP1 endoplasmic reticulum stress pathway via oxidative stress.
Publication Type: Academic Journal
Source(s): Journal of cellular physiology [J Cell Physiol] 2023 Jan; Vol. 238 (1), pp. 151-164. Date of Electronic Publication: 2022 Nov 12.
Abstract: Nanoplastics (NPs) pollution poses a huge threat to the ecosystem and has become one of the environmental pollutants that have attracted much attention. There is increasing evidence that both oxidative stress and endoplasmic reticulum stress (ERS) are ...
Genome-wide screening and identification of potential kinases involved in endoplasmic reticulum stress responses.
Publication Type: Academic Journal
Source(s): Life sciences [Life Sci] 2023 Mar 15; Vol. 317, pp. 121452. Date of Electronic Publication: 2023 Jan 30.
Abstract: Aim: This study aims to identify endoplasmic reticulum stress response elements (ERSE) in the human genome to explore potentially regulated genes, including kinases and transcription factors, involved in the endoplasmic reticulum (ER) stress and its re...
Redox Signaling and Stress in Inherited Myopathies.
Publication Type: Academic Journal
Source(s): Antioxidants & redox signaling [Antioxid Redox Signal] 2022 Aug; Vol. 37 (4-6), pp. 301-323. Date of Electronic Publication: 2022 Apr 18.
Abstract: Significance: Reactive oxygen species (ROS) are highly reactive compounds that behave like a double-edged sword; they damage cellular structures and act as second messengers in signal transduction. Mitochondria and endoplasmic reticulum (ER) a...
METTL3 mediates osteoblast apoptosis by regulating endoplasmic reticulum stress during LPS-induced inflammation.
Publication Type: Academic Journal
Source(s): Cellular signalling [Cell Signal] 2022 Jul; Vol. 95, pp. 110335. Date of Electronic Publication: 2022 Apr 21.
Abstract: Osteoblast apoptosis is a prominent factor for disrupting skeletal homeostasis in multiple inflammatory bone diseases. METTL3, a key methyltransferase that catalyzes the N6-methyladenosine (m 6 A) modification of mRNA, has recently been shown to exert ...
Endogenous BiP reporter system for simultaneous identification of ER stress and antibody production in Chinese hamster ovary cells.
Publication Type: Academic Journal
Source(s): Metabolic engineering [Metab Eng] 2022 Jul; Vol. 72, pp. 35-45. Date of Electronic Publication: 2022 Feb 17.
Abstract: As the biopharmaceutical industry expands, improving the production of therapeutic proteins using Chinese hamster ovary (CHO) cells is important. However, excessive and complicated protein production causes protein misfolding and triggers endoplasmic r...
Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress.
Publication Type: Academic Journal
Source(s): Cells [Cells] 2023 Jan 25; Vol. 12 (3). Date of Electronic Publication: 2023 Jan 25.
Abstract: Through kidney transplantation, ischemia/reperfusion is known to induce tissular injury due to cell energy shortage, oxidative stress, and endoplasmic reticulum (ER) stress. ER stress stems from an accumulation of unfolded or misfolded proteins in the ...
Atg8 and Ire1 in combination regulate the autophagy-related endoplasmic reticulum stress response in Candida albicans.
Publication Type: Academic Journal
Source(s): Research in microbiology [Res Microbiol] 2023 Mar-Apr; Vol. 174 (3), pp. 103996. Date of Electronic Publication: 2022 Oct 31.
Abstract: The unfolded protein response (UPR) is an important pathway to prevent endoplasmic reticulum (ER) stress in eukaryotic cells. In Saccharomyces cerevisiae, Ire1 is a key regulatory factor required for HAC1 gene splicing for further production of functio...