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Conjugated Linoleic Acids Have Anti-Inflammatory Effects in Cultured Endothelial Cells.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Jan 03; Vol. 24 (1). Date of Electronic Publication: 2023 Jan 03.
Abstract: Conjugated linoleic acid (CLA) isomers may have a role in preventing atherosclerosis through the modulation of inflammation, particularly of the endothelium. However, whether low concentrations of CLAs are able to affect basal unstimulated endothelial ...
Synergistic anti-inflammatory effects and mechanisms of the combination of resveratrol and curcumin in human vascular endothelial cells and rodent aorta.
Publication Type: Academic Journal
Source(s): The Journal of nutritional biochemistry [J Nutr Biochem] 2022 Oct; Vol. 108, pp. 109083. Date of Electronic Publication: 2022 Jun 10.
Abstract: Chronic increased pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) play critical roles in the development of endothelial dysfunction and therefore induce cardiovascular disease. Although phytochemicals have the potential ability t...
Expression of anti and pro-inflammatory genes in human endothelial cells activated by 25-hydroxycholesterol: A comparison of rivaroxaban and dabigatran.
Publication Type: Academic Journal
Source(s): Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Aug; Vol. 49 (8), pp. 805-812. Date of Electronic Publication: 2022 Jun 08.
Abstract: Atherosclerosis is associated with a haemostatic imbalance characterized by excessive activation of pro-inflammatory and pro-coagulant pathways. Non-vitamin K antagonists oral anticoagulant (NOACs) may reduce the incidence of cardiovascular events, cer...
Rheum rhaponticum and Rheum rhabarbarum Extracts as Modulators of Endothelial Cell Inflammatory Response.
Publication Type: Academic Journal
Source(s): Nutrients [Nutrients] 2023 Feb 14; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 14.
Abstract: Background: Inflammation, endothelial dysfunction, and alterations in blood physiology are key factors contributing to atherosclerosis and other cardiovascular disorders. Hence, modulation of endothelial function and reducing its pro-inflammatory and p...
Effects of Y-27632, a Rho-associated Kinase Inhibitor, on Human Corneal Endothelial Cells Cultured by Isolating Human Corneal Endothelial Progenitor Cells.
Publication Type: Academic Journal
Source(s): Korean journal of ophthalmology : KJO [Korean J Ophthalmol] 2023 Feb; Vol. 37 (1), pp. 31-41. Date of Electronic Publication: 2022 Dec 22.
Abstract: Conclusions: Y-27632 enabled the isolation and expansion of HCEPs. It also enhanced the proliferation, viability, and migration of differentiated HCEPs.Methods: HCEPs were isolated and expanded in a medium with and without 10μM Y-27632, and then differ...
Sb -Phenyl- N -methyl-5,6,7,12-tetrahydrodibenz[ c,f ][1,5]azastibocine Induces Perlecan Core Protein Synthesis in Cultured Vascular Endothelial Cells.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Feb 11; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 11.
Abstract: Vascular endothelial cells synthesize and secrete perlecan, a large heparan sulfate proteoglycan that increases the anticoagulant activity of vascular endothelium by inducing antithrombin III and intensifying fibroblast growth factor (FGF)-2 activity t...
Resolvin E1 attenuates doxorubicin-induced endothelial senescence by modulating NLRP3 inflammasome activation.
Publication Type: Academic Journal
Source(s): Biochemical pharmacology [Biochem Pharmacol] 2022 Jul; Vol. 201, pp. 115078. Date of Electronic Publication: 2022 May 10.
Abstract: Endothelial cell senescence contributes to chronic inflammation and endothelial dysfunction, while favoring cardiovascular disorders and frailty. Senescent cells acquire a pro-inflammatory secretory phenotype that further propagates inflammation and se...
Butein and Frondoside-A Combination Exhibits Additive Anti-Cancer Effects on Tumor Cell Viability, Colony Growth, and Invasion and Synergism on Endothelial Cell Migration.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2021 Dec 31; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 31.
Abstract: Despite the significant advances in targeted- and immuno-therapies, lung and breast cancer are at the top list of cancer incidence and mortality worldwide as of 2020. Combination therapy consisting of a mixture of different drugs taken at once is curre...
Effects of Human Deciduous Dental Pulp-Derived Mesenchymal Stem Cell-Derived Conditioned Medium on the Metabolism of HUVECs, Osteoblasts, and BMSCs.
Publication Type: Academic Journal
Source(s): Cells [Cells] 2022 Oct 14; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 14.
Abstract: In this study, we assessed the effects of human deciduous dental pulp-derived mesenchymal stem cell-derived conditioned medium (SHED-CM) on the properties of various cell types. The effects of vascular endothelial growth factor (VEGF) in SHED-CM on the...
Remifentanil pretreatment ameliorates H/R-induced cardiac microvascular endothelial cell dysfunction by regulating the PI3K/Akt/HIF-1α signaling pathway.
Publication Type: Academic Journal
Source(s): Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 7872-7881.
Abstract: Restoration of blood supply through medical or surgical intervention is a commonly adopted method for acute myocardial ischemia, but is also a trigger for cardiac ischemia/reperfusion injury. Studies have shown that remifentanil (REM) displays cardiopr...