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Brain activation during fear extinction recall in unmedicated patients with obsessive-compulsive disorder.
Publication Type: Academic Journal
Source(s): Psychiatry research. Neuroimaging [Psychiatry Res Neuroimaging] 2023 Dec; Vol. 336, pp. 111733. Date of Electronic Publication: 2023 Oct 19.
Abstract: Specific brain activation patterns during fear conditioning and the recall of previously extinguished fear responses have been associated with obsessive-compulsive disorder (OCD). However, further replication studies are necessary. We measured skin-con...
Learning bias predicts fear acquisition under stress but not cognitive flexibility.
Publication Type: Academic Journal
Source(s): Physiology & behavior [Physiol Behav] 2023 Dec 01; Vol. 272, pp. 114384. Date of Electronic Publication: 2023 Oct 20.
Abstract: Individuals differ in their ability to learn from reinforcement and in avoiding punishment, which can be measured by the Probabilistic Selection Task (PST). Recently, some studies have demonstrated that this learning bias is regulated by the dopaminerg...
The interactive effects of different facets of threat uncertainty and cognitive load in shaping fear and anxiety responses.
Publication Type: Academic Journal
Source(s): Psychophysiology [Psychophysiology] 2023 Dec; Vol. 60 (12), pp. e14404. Date of Electronic Publication: 2023 Aug 09.
Abstract: A large body of research indicates that exaggerated response to uncertainty of a future threat is at the core of anxiety and related disorders, underscoring the need for a better understanding of the underlying mechanisms. Although behavioral and neuro...
Combining impact of velocity, fear and refuge for the predator-prey dynamics.
Publication Type: Academic Journal
Source(s): Journal of biological dynamics [J Biol Dyn] 2023 Dec; Vol. 17 (1), pp. 2181989.
Abstract: We develop a deterministic predator-prey compartmental model to investigate the impact of their velocities on their interactions. Prey hides in a refuge area and comes out of this area when predation pressure declines. To avoid predation, prey can limi...
A network analytic investigation of avoidance, dampening, and devaluation of positivity.
Publication Type: Academic Journal
Source(s): Journal of behavior therapy and experimental psychiatry [J Behav Ther Exp Psychiatry] 2023 Dec; Vol. 81, pp. 101870. Date of Electronic Publication: 2023 May 06.
Abstract: Background and Objectives: Reward Devaluation Theory suggests that devaluation of positivity may be integral in understanding depression (Winer & Salem, 2016). Specifically, the anticipatory (e.g., fear of happiness) and responsive (e.g., dampening) be...
Heterotypic Stressors Unmask Behavioral Influences of PMAT Deficiency in Mice.
Publication Type: Academic Journal
Source(s): International journal of molecular sciences [Int J Mol Sci] 2023 Nov 18; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 18.
Abstract: Certain life stressors having enduring physiological and behavioral consequences, in part by eliciting dramatic signaling shifts in monoamine neurotransmitters. High monoamine levels can overwhelm selective transporters like the serotonin transporter. ...
Behavioral and genetic architecture of fear conditioning and related phenotypes.
Publication Type: Academic Journal
Source(s): Neurobiology of learning and memory [Neurobiol Learn Mem] 2023 Nov; Vol. 205, pp. 107837. Date of Electronic Publication: 2023 Oct 05.
Abstract: Contextual fear conditioning is a form of Pavlovian learning during which an organism learns to fear previously neutral stimuli following their close temporal presentation with an aversive stimulus. In mouse models, freezing behavior is typically used ...
Increased hippocampal CREB phosphorylation after retrieval of remote contextual fear memories in Carioca high-conditioned freezing rats.
Publication Type: Academic Journal
Source(s): Neurobiology of learning and memory [Neurobiol Learn Mem] 2023 Nov; Vol. 205, pp. 107828. Date of Electronic Publication: 2023 Sep 18.
Abstract: The participation of the hippocampal formation in consolidation and reconsolidation of contextual fear memories has been widely recognized and known to be dependent on the activation of the cAMP response element (CRE) binding protein (CREB) pathway. Re...
The impact of physical exercise on the consolidation of fear extinction memories.
Publication Type: Academic Journal
Source(s): Psychophysiology [Psychophysiology] 2023 Nov; Vol. 60 (11), pp. e14373. Date of Electronic Publication: 2023 Jun 23.
Abstract: Based on the mechanisms of fear extinction, exposure therapy is the most common treatment for anxiety disorders. However, extinguished fear responses can reemerge even after successful treatment. Novel interventions enhancing exposure therapy efficacy ...
The overgeneralization of pain-related fear in individuals with higher pain sensitivity: A behavioral and event-related potential study.
Publication Type: Academic Journal
Source(s): Brain research [Brain Res] 2023 Nov 01; Vol. 1818, pp. 148473. Date of Electronic Publication: 2023 Jul 04.
Abstract: Fear generalization contributes to the development and maintenance of pain. Pain sensitivity has been proposed to predict the strength of fear responses to aversive stimuli. However, whether individual variation in pain sensitivity affects pain-related...