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Fluticasone furoate plus vilanterol in patients with moderate persistent asthma: a cost-utility analysis.
Publication Type: Academic Journal
Source(s): The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2023 Feb; Vol. 60 (2), pp. 377-384. Date of Electronic Publication: 2022 Mar 17.
Abstract: Background: In recent years, the combination of fluticasone furoate and vilanterol (FF/VI) has emerged as an alternative therapy, since it is administered every 24 h, in contrast to other ICS/LABAs such as fluticasone propionate plus salmeterol (FP/Sal...
Olopatadine/mometasone (Ryaltris) for allergic rhinitis.
Publication Type: Academic Journal
Source(s): The Medical letter on drugs and therapeutics [Med Lett Drugs Ther] 2023 Jan 23; Vol. 65 (1668), pp. 12-14.
Therapeutic potential of cationic bilosomes in the treatment of carrageenan-induced rat arthritis via fluticasone propionate gel.
Publication Type: Academic Journal
Source(s): International journal of pharmaceutics [Int J Pharm] 2023 Mar 25; Vol. 635, pp. 122776. Date of Electronic Publication: 2023 Feb 23.
Abstract: Arthritis is a debilitating disease that affects the patient's mobility and quality of life. This study focused on the development and optimization of a cationic nanosized bilosomal formula for the efficient transdermal treatment of arthritis. An optim...
Eustachian Tube Dysfunction in Children with Adenoid Hypertrophy: The Effect of Intranasal Azelastine-Fluticasone Spray Treatment on Middle Ear Ventilation and Adenoid Tissue.
Publication Type: Academic Journal
Source(s): Ear, nose, & throat journal [Ear Nose Throat J] 2023 Mar; Vol. 102 (3), pp. 198-203. Date of Electronic Publication: 2022 Nov 23.
Abstract: Objectives: Eustachian tube dysfunction (ETD) is frequent in children with adenoid hypertrophy (AH). Although the most common treatment of AH is surgical removal of adenoid tissue, numerous studies have reported the efficacy of intranasal steroids. The...
Effect of MP-AzeFlu compared to monotherapy on COX-2, PGE 2 , and EP2 gene expression in upper airway mucosa.
Publication Type: Academic Journal
Source(s): Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Jan; Vol. 11 (1), pp. e709.
Abstract: MP-AzeFlu (intranasal fluticasone and azelastine) has been widely studied and has demonstrated efficacy in Allergic rhinitis with a superior effect compared to these drugs administered individually; however, the mechanism by which MP-AzeFlu produces th...
Comparison of Sinus Deposition from an Aqueous Nasal Spray and Pressurised MDI in a Post-Endoscopic Sinus Surgery Nasal Replica.
Publication Type: Academic Journal
Source(s): Pharmaceutical research [Pharm Res] 2022 Feb; Vol. 39 (2), pp. 317-327. Date of Electronic Publication: 2022 Feb 08.
Abstract: Background: Optimising intranasal distribution and retention of topical therapy is essential for effectively managing patients with chronic rhinosinusitis, including those that have had functional endoscopic sinus surgery (FESS). This study presents a ...
Therapeutic Response to Single-Inhaler Triple Therapies in Moderate-to-Severe COPD.
Publication Type: Academic Journal
Source(s): Respiratory care [Respir Care] 2023 Mar; Vol. 68 (3), pp. 330-337.
Abstract: Background: COPD is characterized by progressive and irreversible air flow limitations. Single-inhaler therapies (SITTs) incorporating an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting β 2 -agonist have been shown to eff...
Corticosteroid treatment attenuates anxiety and mPFC-amygdala circuit dysfunction in allergic asthma.
Publication Type: Academic Journal
Source(s): Life sciences [Life Sci] 2023 Feb 15; Vol. 315, pp. 121373. Date of Electronic Publication: 2023 Jan 05.
Abstract: Aims: Allergic asthma is associated with anxiety-related behaviors, leading to poor quality of life. Previous studies mainly described the neuropathophysiology of asthma-induced anxiety. However, the effects of corticosteroids, the most common anti-inf...
Optical photothermal infrared spectroscopy for nanochemical analysis of pharmaceutical dry powder aerosols.
Publication Type: Academic Journal
Source(s): International journal of pharmaceutics [Int J Pharm] 2023 Feb 05; Vol. 632, pp. 122563. Date of Electronic Publication: 2022 Dec 28.
Abstract: The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state. The conventional wet assay of the chemical composition of parti...
In Vitro Drug Delivery of a Fixed-Dose Combination of Fluticasone Furoate/Umeclidinium/Vilanterol from a Dry Powder Inhaler.
Publication Type: Academic Journal
Source(s): Journal of aerosol medicine and pulmonary drug delivery [J Aerosol Med Pulm Drug Deliv] 2023 Feb; Vol. 36 (1), pp. 34-43. Date of Electronic Publication: 2023 Jan 25.
Abstract: Background: Dry powder inhalers (DPIs) require patients to impart sufficient energy through inhalation to ensure adequate dose emission, medication deaggregation, and resultant particle sizes suitable for lung deposition. There is an ongoing d...