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Advanced Search Results For "GENES"

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 "GENES"
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Identification of differentially expressed genes and pathways in kidney of ANCA-associated vasculitis by integrated bioinformatics analysis.

Publication Type: Academic Journal

Source(s): Renal failure [Ren Fail] 2022 Dec; Vol. 44 (1), pp. 204-216.

Authors:

Abstract: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systematic of relatively rare autoimmune diseases with unknown cause. Kidney involvement is one of the most common clinical manifestations, and the degree of renal damage i...

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Virtual drug repurposing study for the CGRPR identifies pentagastrin and leuprorelin as putative candidates.

Publication Type: Academic Journal

Source(s): Journal of molecular graphics & modelling [J Mol Graph Model] 2022 Nov; Vol. 116, pp. 108254. Date of Electronic Publication: 2022 Jun 18.

Abstract: Calcitonin gene-related peptide receptor (CGRPR) is a heterodimer consisting of CLR and RAMP1 proteins. Activation of the CGRPR with the endogenous peptide CGRP is known to play a crucial role in migraine pathophysiology. CGRP occupies two regions in t...

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Expression and clinical significance of RAG1 in myelodysplastic syndromes.

Publication Type: Academic Journal

Source(s): Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 1122-1129.

Authors:

Abstract: Objective: To determine the expression level of RAG1 and its clinical significance in myelodysplastic syndromes (MDS).Methods: To explore the candidate genes, the microarray datasets GSE19429, GSE58831, and GSE2779 were downloaded from the Gene Express...

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NetREX-CF integrates incomplete transcription factor data with gene expression to reconstruct gene regulatory networks.

Publication Type: Academic Journal

Source(s): Communications biology [Commun Biol] 2022 Nov 23; Vol. 5 (1), pp. 1282. Date of Electronic Publication: 2022 Nov 23.

Authors:

Abstract: The inference of Gene Regulatory Networks (GRNs) is one of the key challenges in systems biology. Leading algorithms utilize, in addition to gene expression, prior knowledge such as Transcription Factor (TF) DNA binding motifs or results of TF binding ...

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Pituitary-Gland-Based Genes Participates in Intrauterine Growth Restriction in Piglets.

Publication Type: Academic Journal

Source(s): Genes [Genes (Basel)] 2022 Nov 17; Vol. 13 (11). Date of Electronic Publication: 2022 Nov 17.

Authors:

Abstract: Intrauterine growth restriction (IUGR) is a major problem associated with piglet growth performance. The incidence of IUGR is widespread in Rongchang pigs. The pituitary gland is important for regulating growth and metabolism, and research has identifi...

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Validation of suitable reference genes by various algorithms for gene expression analysis in Isodon rubescens under different abiotic stresses.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2022 Nov 15; Vol. 12 (1), pp. 19599. Date of Electronic Publication: 2022 Nov 15.

Authors:

Abstract: Isodon rubescens (Hemsley) H. Hara (Lamiaceae) is a traditional Chinese medicine plant that has been used to treat various human diseases. Oridonin is one of the main active ingredients, and the route of its molecular biosynthesis remains to be determi...

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Paralogous Genes Involved in Embryonic Development: Lessons from the Eye and Other Tissues.

Publication Type: Academic Journal

Source(s): Genes [Genes (Basel)] 2022 Nov 09; Vol. 13 (11). Date of Electronic Publication: 2022 Nov 09.

Authors:

Abstract: During evolution, gene duplications lead to a naturally increased gene dosage. Duplicated genes can be further retained or eliminated over time by purifying selection pressure. The retention probability is increased by functional diversification and by...

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Reliable reference genes and abiotic stress marker genes in Klebsormidium nitens.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2022 Nov 08; Vol. 12 (1), pp. 18988. Date of Electronic Publication: 2022 Nov 08.

Abstract: Microalgae have recently emerged as a key research topic, especially as biological models. Among them, the green alga Klebsormidium nitens, thanks to its particular adaptation to environmental stresses, represents an interesting photosynthetic eukaryot...

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Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene-environment associations.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2022 Nov 04; Vol. 12 (1), pp. 18710. Date of Electronic Publication: 2022 Nov 04.

Abstract: The purpose of this study is to manually and semi-automatically curate a database and develop an R package that will act as a comprehensive resource to understand how biological processes are dysregulated due to interactions with environmental factors....

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Reconstructing horizontal gene flow network to understand prokaryotic evolution.

Publication Type: Academic Journal

Source(s): Open biology [Open Biol] 2022 Nov; Vol. 12 (11), pp. 220169. Date of Electronic Publication: 2022 Nov 30.

Authors:

Abstract: Horizontal gene transfer (HGT) is a major source of phenotypic innovation and a mechanism of niche adaptation in prokaryotes. Quantification of HGT is critical to decipher its myriad roles in microbial evolution and adaptation. Advances in genome seque...

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