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Advanced Search Results For "GENETIC regulation"

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 "GENETIC regulation"
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Bacterial approaches to sensing and responding to respiration and respiration metabolites.

Publication Type: Academic Journal

Source(s): Molecular microbiology [Mol Microbiol] 2021 Oct; Vol. 116 (4), pp. 1009-1021. Date of Electronic Publication: 2021 Aug 25.

Abstract: Bacterial respiration of diverse substrates is a primary contributor to the diversity of life. Respiration also drives alterations in the geosphere and tethers ecological nodes together. It provides organisms with a means to dissipate reductants and ge...

Genetic variant within CDK6 regulates immune response to palbociclib treatment.

Publication Type: Academic Journal

Source(s): Clinical immunology (Orlando, Fla.) [Clin Immunol] 2022 Feb; Vol. 235, pp. 108777. Date of Electronic Publication: 2021 Jun 08.

Abstract: Everyone carries a set of genetic variants that contribute to regulation of the levels of blood cells, with unknown clinical impact. One of them, rs445 within the cell-cycle checkpoint gene CDK6, reduces the levels of myeloid cell types including granu...

ABCC8 is correlated with immune cell infiltration and overall survival in lower grade glioma.

Publication Type: Academic Journal

Source(s): Biocell. 2023, Vol. 47 Issue 1, p109-132. 15p.

Abstract: ATP binding cassette subfamily C member 8 (ABCC8) encodes a protein regulating the ATP-sensitive potassium channel. Whether the level of ABCC8 mRNA in lower grade glioma (LGG) correlates with immune cell infiltration and patient outcomes has not been e...

Identification of the Hub Genes and Potential Regulation Network in Chronic Hepatitis B via Bioinformatics Analysis.

Publication Type: Academic Journal

Source(s): Disease Markers. 9/23/2022, p1-12. 12p.

Abstract: Background. Chronic hepatitis B (CHB) is a serious infectious disease which is induced by hepatitis B virus (HBV) infection. This project was conducted to reveal the potential mechanism in CHB development via analyzing the public clinical data. Methods...

Perfecting or selecting? When 'kinds of children' are the objective.

Publication Type: Academic Journal

Source(s): Journal of Marketing Management. May2022, Vol. 38 Issue 5/6, p478-482. 5p.


Abstract: With news of the birth of the world's first babies following embryo gene editing breaking in November 2018, transhumanist aspirations to biotechnologically augment human capacities seem that much closer to reality. In this commentary, I argue that rece...

Dynamic molecular evolution of a supergene with suppressed recombination in white-throated sparrows.

Publication Type: Academic Journal

Source(s): eLife. 8/30/2022, p1-24. 24p.

Abstract: In white-throated sparrows, two alternative morphs differing in plumage and behavior segregate with a large chromosomal rearrangement. As with sex chromosomes such as the mammalian Y, the rearranged version of chromosome two (ZAL2m) is in a near-consta...

Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways.

Publication Type: Academic Journal

Source(s): eLife. 9/21/2022, p1-31. 31p.

Abstract: How cells control gene expression is a fundamental question. The relative contribution of protein-level and RNA-level regulation to this process remains unclear. Here, we perform a proteogenomic analysis of tumors and untransformed cells containing som...

Profiles of Acetylation Regulation Genes Contribute to Malignant Progression and Have a Clinical Prognostic Impact on Liver Cancer.

Publication Type: Academic Journal

Source(s): Disease Markers. 9/10/2022, p1-19. 19p.

Abstract: Background. Several studies have demonstrated that acetylation was involved in the process of liver cancer. This study aimed to establish an effective predictive prognostic model using acetylation regulation genes in liver cancer. Methods. Two datasets...

Transcriptional changes through menstrual cycle reveal a global transcriptional derepression underlying the molecular mechanism involved in the window of implantation.

Publication Type: Academic Journal

Source(s): Molecular human reproduction [Mol Hum Reprod] 2021 May 08; Vol. 27 (5).

Abstract: The human endometrium is a dynamic tissue that only is receptive to host the embryo during a brief time in the middle secretory phase, called the window of implantation (WOI). Despite its importance, regulation of the menstrual cycle remains incomplete...

Differential Expression of Hub Genes and Activation of p53 by Anti-cancer Compound Curaxin CBL0137.

Publication Type: Academic Journal

Source(s): American Journal of Undergraduate Research. Sep2022, Vol. 19 Issue 2, p33-42. 10p.

Abstract: Cancer is a global concern, and there is a need for effective drugs. CBL0137 is a small water-soluble molecule and a new secondgeneration compound in the family of curaxins with potential anti-cancer activity. Curaxins in general, including CBL0137, in...