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Characteristics of tear meniscus using a spectral domain optical coherence tomography in medically controlled glaucoma.
Publication Type: Academic Journal
Source(s): Indian journal of ophthalmology [Indian J Ophthalmol] 2023 Jul; Vol. 71 (7), pp. 2704-2710.
Abstract: Purpose: To compare the tear meniscus height (TMH) and tear meniscus depth (TMD) between medically controlled glaucoma subjects and age-matched controls.Methods: This prospective, cross-sectional, observational study included 50 patients with medically...
Intraocular Adeno-Associated Virus-Mediated Transgene Endothelin-1 Delivery to the Rat Eye Induces Functional Changes Indicative of Retinal Ischemia-A Potential Chronic Glaucoma Model.
Publication Type: Academic Journal
Source(s): Cells [Cells] 2023 Aug 02; Vol. 12 (15). Date of Electronic Publication: 2023 Aug 02.
Abstract: Endothelin-1 (ET-1) overactivity has been implicated as a factor contributing to glaucomatous neuropathy, and it has been utilized in animal models of retinal ischemia. The functional effects of long-term ET-1 exposure and possible compensatory mechani...
Inhibition of NOX4 with GLX351322 alleviates acute ocular hypertension-induced retinal inflammation and injury by suppressing ROS mediated redox-sensitive factors activation.
Publication Type: Academic Journal
Source(s): Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Sep; Vol. 165, pp. 115052. Date of Electronic Publication: 2023 Jul 01.
Abstract: Reactive oxygen species (ROS) overproduction plays an essential role in the etiology of ischemic/hypoxic retinopathy caused by acute glaucoma. NADPH oxidase (NOX) 4 was discovered as one of the main sources of ROS in glaucoma. However, the role and pot...
Assessment of corneal sublayer thickness changes in glaucoma patients using optical coherence tomography and correlation of epithelial layer thinning with dry eye monitoring.
Publication Type: Academic Journal
Source(s): Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2023 Sep; Vol. 43, pp. 103728. Date of Electronic Publication: 2023 Jul 28.
Abstract: Background: In this study, we aimed to assess the central corneal epithelial thickness (CET), central corneal stromal thickness (CST), and total central corneal thickness (CCT) thinning relationships with dry eye development monitoring and underestimat...
Randomized Multicenter Clinical Trial Comparing 0.1% Brimonidine/0.5% Timolol Versus 1% Dorzolamide/0.5% Timolol as Adjuncts to Prostaglandin Analogues: Aibeta Crossover Study.
Publication Type: Academic Journal
Source(s): Advances in therapy [Adv Ther] 2023 Sep; Vol. 40 (9), pp. 4074-4092. Date of Electronic Publication: 2023 Jul 15.
Abstract: Introduction: This multicenter, randomized, comparative, and investigator-masked crossover clinical trial sought to compare the efficacy and tolerability of fixed combinations of 0.1% brimonidine/0.5% timolol (BTFC) versus 1% dorzolamide/0.5% timolol (...
Primary Open-Angle Glaucoma Progression in Glaucoma Patients with Unchanged Topical Treatment over 3 Years - Retrospective Observational Cohort Analysis.
Publication Type: Academic Journal
Source(s): Klinische Monatsblatter fur Augenheilkunde [Klin Monbl Augenheilkd] 2023 Apr; Vol. 240 (4), pp. 467-471. Date of Electronic Publication: 2023 Apr 25.
Abstract: Background: Lowering intraocular pressure (IOP) is a mainstay of glaucoma therapy. It is, however, still an open question whether a comparable level of long-term IOP lowering achieved by different medications results in comparable protection for the re...
Effectiveness and safety of VISULAS ® green selective laser trabeculoplasty: a prospective, interventional multicenter clinical investigation.
Publication Type: Academic Journal
Source(s): International ophthalmology [Int Ophthalmol] 2023 Jul; Vol. 43 (7), pp. 2215-2224. Date of Electronic Publication: 2022 Dec 26.
Abstract: Purpose: To evaluate the effectiveness and safety of Selective Laser Trabeculoplasty (SLT) with the SLT mode of the VISULAS ® green laser in patients with primary open-angle glaucoma (POAG).Methods: This prospective, interventional multicenter clinical...
24-Hour efficacy of single primary selective laser trabeculoplasty versus latanoprost eye drops for Naïve primary open-angle glaucoma and ocular hypertension patients.
Publication Type: Academic Journal
Source(s): Scientific reports [Sci Rep] 2023 Jul 27; Vol. 13 (1), pp. 12179. Date of Electronic Publication: 2023 Jul 27.
Abstract: This prospective, observer-masked, randomized clinical trial was conducted between December 2018 and June 2021 at Eye Hospital, China Academy of Chinese Medical Sciences. A total of 45 glaucoma patients from Beijing, China, were enrolled in this clinic...
A randomized clinical trial comparing three fixed combinations of bimatoprost with timolol in patients with open-angle glaucoma or ocular hypertension.
Publication Type: Academic Journal
Source(s): Current medical research and opinion [Curr Med Res Opin] 2023 May; Vol. 39 (5), pp. 775-783. Date of Electronic Publication: 2023 Apr 17.
Abstract: Objective: To compare the efficacy and safety of two fixed combination, preservative-free eye drops (bimatoprost 0.01% in combination with either timolol 0.1% or 0.5%) in a gel formulation, with bimatoprost 0.03%/timolol 0.5% in patients with open-angl...
Practice patterns and costs of glaucoma treatment in Japan.
Publication Type: Academic Journal
Source(s): Japanese journal of ophthalmology [Jpn J Ophthalmol] 2023 Sep; Vol. 67 (5), pp. 590-601. Date of Electronic Publication: 2023 Jun 24.
Abstract: Purpose: Understanding the practice patterns and costs of glaucoma care in real-world clinical settings is important for optimizing medical expenses. However, glaucoma treatment trends and associated costs in Japan are unknown. We aimed to unveil glauc...