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Advanced Search Results For "HYPOXEMIA"

1 - 10 of 49,385 results for
 "HYPOXEMIA"
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Unravelling the characterization of hypoxia‐inducible factor‐1α (HIF‐1α) and antioxidant enzymes in clam Cyclina sinensis in response to hypoxia.

Publication Type: Academic Journal

Source(s): Aquaculture Research. Dec2022, Vol. 53 Issue 17, p5937-5945. 9p.

Abstract: Aquatic hypoxia has negative or detrimental effects on clams. To cope with hypoxia stress, a complex series of physiological and biochemical strategies can be employed in clams. Hypoxia‐inducible factor‐1α (HIF‐1α) and antioxidant enzymes are commonly ...

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Activities of Catalase and Peroxidase in Wheat and Rice Plants under Conditions of Anoxia and Post-Anoxic Aeration.

Publication Type: Academic Journal

Source(s): Russian Journal of Plant Physiology. Dec2022, Vol. 69 Issue 6, p1-15. 15p.

Abstract: Effects of anoxia and subsequent reaeration on formation of hydrogen peroxide, and activities of catalase (EC 1.11.1.6) and guaiacol peroxidase (EC 1.11.1.7) were studied in wheat and rice plants that are contrasting in their tolerance to hypoxia. It w...

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A 77-Year-Old Woman With Capillary Hypoxia and Perioral Cyanosis.

Publication Type: Academic Journal

Source(s): CHEST. Dec2022, Vol. 162 Issue 6, pe295-e299. 5p.

Abstract: A 77-year-old woman with asthma, hypothyroidism, irritable bowel syndrome, overactive bladder, and multiple rheumatologic conditions was sent from the clinic to the ED for evaluation of hypoxia. In the clinic, she reported dizziness without shortness o...

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Targeted Singlet Oxygen Delivery: A Bioorthogonal Metabolic Shunt Linking Hypoxia to Fast Singlet Oxygen Release.

Publication Type: Academic Journal

Source(s): Angewandte Chemie. 11/21/2022, Vol. 134 Issue 47, p1-5. 5p.

Abstract: Singlet oxygen can be generated by thermal cycloreversion of aromatic endoperoxides. However, for any practical potential of chemically generated singlet oxygen within a therapeutic context, the time and place of the release of this cytotoxic species m...

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Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor.

Publication Type: Academic Journal

Source(s): Cells (2073-4409). Nov2022, Vol. 11 Issue 22, p3595. 18p.

Abstract: The HIF-1 and HIF-2 (HIF1/2) hypoxia responses are frequently upregulated in cancers, and HIF1/2 inhibitors are being developed as anticancer drugs. How could cancers resist anti-HIF1/2 therapy? We studied metabolic and molecular adaptations of HIF-1β-...

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Polar localization of CheO under hypoxia promotes Campylobacter jejuni chemotactic behavior within host.

Publication Type: Academic Journal

Source(s): PLoS Pathogens. 11/3/2022, Vol. 18 Issue 11, p1-24. 24p.

Abstract: Campylobacter jejuni is a food-borne zoonotic pathogen of worldwide concern and the leading cause of bacterial diarrheal disease. In contrast to other enteric pathogens, C. jejuni has strict growth and nutritional requirements but lacks many virulence ...

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The effects of the superoxide dismutase mimetic, MnTMPyP, post hypoxia and oxygen glucose deprivation in isolated rat hippocampal slices.

Publication Type: Academic Journal

Source(s): Brain Research Bulletin. Nov2022, Vol. 190, p105-115. 11p.

Abstract: The contributions of hypoxia, oxygen glucose deprivation (OGD) and oxidative stress, to the pathophysiology of acute ischemic stroke (AIS) are well established and can lead to disruptions in synaptic signaling. Antioxidant compounds have previously bee...

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Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II.

Publication Type: Academic Journal

Source(s): Cells (2073-4409). Nov2022, Vol. 11 Issue 21, p3424. 16p.

Abstract: Hypoxia stabilizes the transcription factor HIF-1α, which promotes the transcription of many genes essential to adapt to reduced oxygen levels. Besides proline hydroxylation, expression of HIF-1α is also regulated by a range of other posttranslational ...

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Cross-adaptation between heat and hypoxia: mechanistic insights into aerobic exercise performance.

Publication Type: Academic Journal

Source(s): American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Nov2022, Vol. 323 Issue 5, pR661-R669. 9p.

Abstract: Acclima(tiza)tion to heat or hypoxia enhances work capacity in hot and hypoxic environmental conditions, respectively; an acclimation response is considered to be mediated by stimuli-specific molecular/systemic adaptations and potentially facilitated b...

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Disturbance of Hypoxia Response and Its Implications in Kidney Diseases.

Publication Type: Academic Journal

Source(s): Antioxidants & Redox Signaling. Nov2022, Vol. 37 Issue 13, p936-955. 20p.

Abstract: Significance: The disturbance of the hypoxia response system is closely related to human diseases, because it is essential for the maintenance of homeostasis. Given the significant role of the hypoxia response system in human health, therapeutic applic...

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