Advanced Search Results For "HYPOXEMIA"
Your filters
Searching for molecular hypoxia sensors among oxygen-dependent enzymes.
Publication Type: Academic Journal
Source(s): eLife. 7/26/2023, p1-35. 35p.
Abstract: The ability to sense and respond to changes in cellular oxygen levels is critical for aerobic organisms and requires a molecular oxygen sensor. The prototypical sensor is the oxygen-dependent enzyme PHD: hypoxia inhibits its ability to hydroxylate the ...
Determinants of Severe Nocturnal Hypoxemia in Adults with Chronic Thromboembolic Pulmonary Hypertension and Sleep-Related Breathing Disorders.
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine. Jul2023, Vol. 12 Issue 14, p4639. 12p.
Abstract: Objectives: We aimed to investigate the occurrence of sleep-related breathing disorders (SRBDs) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and addressed the effect of pulmonary hemodynamics and SRBD indices on the severity o...
Effects of Normobaric Hypoxia and Adrenergic Blockade over 72 h on Cardiac Function in Rats.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 14, p11417. 20p.
Abstract: In rats, acute normobaric hypoxia depressed left ventricular (LV) inotropic function. After 24 h of hypoxic exposure, a slight recovery of LV function occurred. We speculated that prolonged hypoxia (72 h) would induce acclimatization and, hence, recove...
Hypoxia Activates HIF-1α and Affects Gene Expression and Transcriptional Regulation of PHD in Tegillarca granosa.
Publication Type: Academic Journal
Source(s): Fishes (MDPI AG). Jul2023, Vol. 8 Issue 7, p359. 16p.
Abstract: Hypoxia is a common challenge faced by mollusks, and the role of hypoxia-inducible factor-1α (HIF-1α) in regulating related target genes under hypoxia in Tegillarca granosa (Tg) remains unclear. In this study, we identified gene HIF-1α and further expl...
Biocompatible Phosphorescent O 2 Sensors Based on Ir(III) Complexes for In Vivo Hypoxia Imaging.
Publication Type: Academic Journal
Source(s): Biosensors (2079-6374). Jul2023, Vol. 13 Issue 7, p680. 17p.
Abstract: In this work, we obtained three new phosphorescent iridium complexes (Ir1–Ir3) of general stoichiometry [Ir(N^C)2(N^N)]Cl decorated with oligo(ethylene glycol) fragments to make them water-soluble and biocompatible, as well as to protect them from aggr...
Lactate and pH values in newborns with a history of acute fetal distress.
Publication Type: Academic Journal
Source(s): Boletín Médico del Hospital Infantil de México. jul/ago2023, Vol. 80 Issue 4, p247-252. 6p.
Abstract: Background: Acute fetal distress (AFD) is a condition that requires timely diagnosis because it generates hypoxia, acidosis, and even intrauterine death. This study aimed to determine lactate and pH values in the umbilical cord in full-term newborns (N...
Atomic Force Microscopy and High-Resolution Spectrophotometry for Study of Anoxemia and Normoxemia in Model Experiment In Vitro.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p11043. 21p.
Abstract: The oxygen content in the blood may decrease under the influence of various physicochemical factors and different diseases. The state of hypoxemia is especially dangerous for critically ill patients. In this paper, we describe and analyze the changes i...
Physiological Responses of Anemic Women to Exercise under Hypoxic Conditions.
Publication Type: Academic Journal
Source(s): Physiologia. Jun2023, Vol. 3 Issue 2, p247-258. 12p.
Abstract: When combining two conditions of reduced oxygen availability, anemia and hypoxia, human physiological responses are highly challenged to maintain arterial oxygen delivery, especially during whole-body exercise. The aim of this study was to compare the ...
Non-enzymatic antioxidant blood plasma profile in the period of high training loads of elite speed skaters in the altitude.
Publication Type: Academic Journal
Source(s): Sports Medicine & Health Science (SMHS). Jun2023, Vol. 5 Issue 2, p120-127. 8p.
Abstract: At the altitude, hypoxia and training load are key factors in the development of oxidative stress. Altitude-induced oxidative stress is developed due to the depletion of antioxidant potential. In the current study, we examined the non-enzymatic antioxi...
The Effectiveness of L-arginine in Clinical Conditions Associated with Hypoxia.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. May2023, Vol. 24 Issue 9, p8205. 24p.
Abstract: The review summarises the data of the last 50 years on the effectiveness of the amino acid L-arginine in therapeutic practice in conditions accompanied by different-origin hypoxia. The aim of this review was to analyse the literature and our research d...