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Advanced Search Results For "IMMUNOSUPPRESSIVE agents"

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 "IMMUNOSUPPRESSIVE agents"
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[Biosynthesis of immunosuppressant tacrolimus: a review].

Publication Type: Academic Journal

Source(s): Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2023 Aug 25; Vol. 39 (8), pp. 3095-3110.

Authors:

Abstract: Tacrolimus (FK506) is a 23-membered macrolide with immunosuppressant activity that is widely used clinically for treating the rejection after organ transplantation. The research on tacrolimus production was mainly focused on biosynthesis methods, withi...

Transplant Trial Watch.

Publication Type: Editorial & Opinion

Source(s): Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2023 Jul 27; Vol. 36, pp. 11742. Date of Electronic Publication: 2023 Jul 27 (Print Publication: 2023).

Authors:

Abstract: Competing Interests: The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series.

Publication Type: Academic Journal

Source(s): Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Jun; Vol. 11 (3), pp. e01103.

Abstract: Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored using therapeutic drug monitoring. We present three cases in which MPA exposure...

Do the drug doses of conventional synthetic DMARDs used for the treatment of biologic/targeted-synthetic DMARDs naive rheumatoid arthritis patients affect QuantiFERON-TB Gold Plus test results?

Publication Type: Academic Journal

Source(s): Rheumatology international [Rheumatol Int] 2023 Aug; Vol. 43 (8), pp. 1445-1451. Date of Electronic Publication: 2023 Apr 01.

Abstract: We aimed to obtain the effects of immunosuppressive doses on the QuantiFERON-TB Gold Plus (QFT-Plus) test results in Rheumatoid Arthritis (RA) patients. Besides this, the impact of the TB2 tube in QFT-Plus test was also investigated. This study include...

An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil's Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer.

Publication Type: Academic Journal

Source(s): Molecules (Basel, Switzerland) [Molecules] 2023 Aug 01; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 01.

Abstract: Antimetabolites, especially 5-fluorouracil, are commonly used clinically to treat breast, colon, and other cancers. However, their side effects and inefficiency in monotherapy have prompted further searches for new combinations. Thus, the anticancer ef...

Successful treatment of urticarial vasculitis with omalizumab in children: a case series.

Publication Type: Academic Journal

Source(s): Clinical and experimental dermatology [Clin Exp Dermatol] 2023 Sep 19; Vol. 48 (10), pp. 1145-1148.

Authors:

Abstract: Urticarial vasculitis (UV) is a small vessel leucocytoclastic vasculitis, which often needs to be distinguished from urticaria and other dermatoses. Treatment of UV in children is challenging because of the unsatisfying efficacy of antihistamines and t...

Age and memory B cells at baseline are associated with risk of relapse and memory B-cell reappearance following anti-CD20 treatment in pediatric frequently-relapsing/steroid-dependent nephrotic syndrome.

Publication Type: Academic Journal

Source(s): Kidney international [Kidney Int] 2023 Sep; Vol. 104 (3), pp. 577-586. Date of Electronic Publication: 2023 Jun 28.

Abstract: B-cell depleting anti-CD20 monoclonal antibodies, such as rituximab, have proven efficacy in children with frequently-relapsing/steroid-dependent nephrotic syndrome (FR/SDNS). However, drug-free remission is variable and specific baseline markers predi...

Management of dental care of patients on immunosuppressive drugs for chronic immune-related inflammatory diseases: a survey of French dentists' practices.

Publication Type: Academic Journal

Source(s): BMC oral health [BMC Oral Health] 2023 Aug 09; Vol. 23 (1), pp. 545. Date of Electronic Publication: 2023 Aug 09.

Abstract: Objectives: The aim of the study was to provide an overview of the practices of French general dentists (GDs) and specialists (SDs) concerning the management of patients with inflammatory bowel diseases (IBDs), rheumatic inflammatory diseases (IRDs), a...

Evidence-base for the beneficial effect of nutraceuticals in canine dermatological immune-mediated inflammatory diseases - A literature review.

Publication Type: Academic Journal

Source(s): Veterinary dermatology [Vet Dermatol] 2023 Aug; Vol. 34 (4), pp. 266-283. Date of Electronic Publication: 2023 Mar 20.

Abstract: Background: Immune-mediated inflammatory diseases (IMIDs) are associated with an abnormal immune response, resulting in a disturbed homeostasis and chronic inflammation. Most canine dermatological IMIDs (cDIMIDs), such as allergies, autoimmune and immu...

Drug interactions of tacrolimus with letermovir and azole antifungals following hematopoietic stem cell transplantation: A retrospective observational analysis.

Publication Type: Academic Journal

Source(s): Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Aug; Vol. 11 (4), pp. e01120.

Abstract: Tacrolimus interacts with letermovir and azole antifungals, whereas letermovir has nonuniform effects on the pharmacokinetics of azole antifungals. We retrospectively investigated the interaction of tacrolimus (continuous infusion) with letermovir cons...

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