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Advanced Search Results For "INFLUENZA"

1 - 10 of 223,786 results for
 "INFLUENZA"
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Differential Recognition of Computationally Optimized H3 Hemagglutinin Influenza Vaccine Candidates by Human Antibodies.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Aug 24; Vol. 96 (16), pp. e0089622. Date of Electronic Publication: 2022 Aug 02.

Abstract: Among circulating influenza viruses in humans, H3N2 viruses typically evolve faster than other subtypes and have caused disease in millions of people since emerging in 1968. Computationally optimized broadly reactive antigen (COBRA) technology is one s...

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Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Aug 24; Vol. 96 (16), pp. e0097122. Date of Electronic Publication: 2022 Aug 02.

Authors:

Abstract: The continuous antigenic variation of influenza A viruses remains a major hurdle for vaccine selection; however, the molecular determinants and mechanisms of antigenic change remain largely unknown. In this study, two escape mutants were generated by s...

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Immunological Correlates of Prevention of the Onset of Seasonal H3N2 Influenza.

Publication Type: Academic Journal

Source(s): The Journal of infectious diseases [J Infect Dis] 2022 Nov 11; Vol. 226 (10), pp. 1800-1808.

Abstract: On influenza virus infection or vaccination, immune responses occur, including the production of antibodies with various functions that contribute to protection from seasonal influenza virus infection. In the current study, we attempted to identify the...

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Influenza virus and its subtypes circulating during 2018-2019: A hospital-based study from Assam.

Publication Type: Academic Journal

Source(s): Indian journal of medical microbiology [Indian J Med Microbiol] 2022 Oct-Dec; Vol. 40 (4), pp. 525-530. Date of Electronic Publication: 2022 Aug 21.

Abstract: Purpose: Influenza virus can cause serious respiratory illness sometimes resulting in epidemics and pandemics associated with significant morbidity and mortality across the globe. Hence, continuous surveillance of the activity of the influenza virus an...

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Evolutionary Dynamics of Whole-Genome Influenza A/H3N2 Viruses Isolated in Myanmar from 2015 to 2019.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Oct 31; Vol. 14 (11). Date of Electronic Publication: 2022 Oct 31.

Abstract: This study aimed to analyze the genetic and evolutionary characteristics of the influenza A/H3N2 viruses circulating in Myanmar from 2015 to 2019. Whole genomes from 79 virus isolates were amplified using real-time polymerase chain reaction and success...

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Antiviral Effect of Isoquercitrin against Influenza A Viral Infection via Modulating Hemagglutinin and Neuraminidase.

Publication Type: Academic Journal

Source(s): International journal of molecular sciences [Int J Mol Sci] 2022 Oct 28; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 28.

Authors:

Abstract: Isoquercitrin (IQC) is a component abundantly present in many plants and is known to have an anti-viral effect against various viruses. In this study, we demonstrate that IQC exhibits strong anti-influenza A virus infection, and its effect is closely r...

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Immunogenicity and safety of high-dose quadrivalent influenza vaccine in older adults in Taiwan: A phase III, randomized, multi-center study.

Publication Type: Academic Journal

Source(s): Vaccine [Vaccine] 2022 Oct 26; Vol. 40 (45), pp. 6450-6454. Date of Electronic Publication: 2022 Oct 07.

Abstract: Background: High-dose influenza vaccine offers better protection against influenza/associated complications compared with standard-dose formulation. We evaluated immunogenicity and safety of high-dose influenza vaccine (QIV-HD) and standard-dose (QIV-S...

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Respiratory Vaccination with Hemagglutinin Nanoliposomes Protects Mice from Homologous and Heterologous Strains of Influenza Virus.

Publication Type: Academic Journal

Source(s): Journal of virology [J Virol] 2022 Oct 12; Vol. 96 (19), pp. e0100622. Date of Electronic Publication: 2022 Sep 15.

Abstract: Intranasal vaccination offers the potential advantage of needle-free prevention of respiratory pathogens such as influenza viruses with induction of mucosal immune responses. Optimal design of adjuvants and antigen delivery vehicles for intranasal deli...

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Biphasic Waning of Hemagglutination Inhibition Antibody Titers After Influenza Vaccination in Children.

Publication Type: Academic Journal

Source(s): The Journal of infectious diseases [J Infect Dis] 2022 Sep 21; Vol. 226 (6), pp. 1022-1026.

Abstract: We explored the potential for a biphasic pattern in waning of antibody titers after influenza vaccination. We collected blood samples in a randomized controlled trial of influenza vaccination in children and tested them with hemagglutination inhibition...

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Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus.

Publication Type: Academic Journal

Source(s): Viruses [Viruses] 2022 Sep 17; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 17.

Authors:

Abstract: Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e., egg passage adaptation) contribute to the poor vaccine efficacy (VE), but the evoluti...

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