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Intraspecific microdiversity and ecological drivers of lactic acid bacteria in naturally fermented milk ecosystem.
Publication Type: Academic Journal
Source(s): Science bulletin [Sci Bull (Beijing)] 2023 Oct 30; Vol. 68 (20), pp. 2405-2417. Date of Electronic Publication: 2023 Sep 04.
Abstract: Traditional fermented milks are produced by inoculating technique, which selects well-adapted microorganisms that have been passed on through generations. Few reports have used naturally fermented milks as model ecosystems to investigate the mechanism ...
Novel P335-like Phage Resistance Arises from Deletion within Putative Autolysin yccB in Lactococcus lactis .
Publication Type: Academic Journal
Source(s): Viruses [Viruses] 2023 Oct 31; Vol. 15 (11). Date of Electronic Publication: 2023 Oct 31.
Abstract: Lactococcus lactis and Lactococcus cremoris are broadly utilized as starter cultures for fermented dairy products and are inherently impacted by bacteriophage (phage) attacks in the industrial environment. Consequently, the generation of bacteriophage-...
A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis-Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes.
Publication Type: Academic Journal
Source(s): Diabetes [Diabetes] 2023 Oct 01; Vol. 72 (10), pp. 1470-1482.
Abstract: Immunomodulation combined with antigen therapy holds great promise to arrest autoimmune type 1 diabetes, but clinical translation is hampered by a lack of prognostic biomarkers. Low-dose anti-CD3 plus Lactococcus lactis bacteria secreting proinsulin an...
Delineation of a lactococcal conjugation system reveals a restriction-modification evasion system.
Publication Type: Academic Journal
Source(s): Microbial biotechnology [Microb Biotechnol] 2023 Jun; Vol. 16 (6), pp. 1250-1263. Date of Electronic Publication: 2023 Mar 21.
Abstract: Plasmid pUC11B is a 49.3-kb plasmid harboured by the fermented meat isolate Lactococcus lactis subsp. lactis UC11. Among other features, pUC11B encodes a pMRC01-like conjugation system and tetracycline-resistance. In this study, we demonstrate that thi...
Cell-to-cell non-conjugative plasmid transfer between Bacillus subtilis and lactic acid bacteria.
Publication Type: Academic Journal
Source(s): Microbial biotechnology [Microb Biotechnol] 2023 Apr; Vol. 16 (4), pp. 784-798. Date of Electronic Publication: 2022 Dec 22.
Abstract: Bacillus subtilis is a soil-dwelling bacterium that can interact with a plethora of other microorganisms in its natural habitat. Due to the versatile interactions and its ability to form nanotubes, i.e., recently described membrane structures that trad...
Construction of a food-grade gene editing system based on CRISPR-Cas9 and its application in Lactococcus lactis NZ9000.
Publication Type: Academic Journal
Source(s): Biotechnology letters [Biotechnol Lett] 2023 Aug; Vol. 45 (8), pp. 955-966. Date of Electronic Publication: 2023 Jun 02.
Abstract: Clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) system has been widely used in gene editing of various organisms. However, food-grade gene editing systems in lactic acid bacteria are still preliminary. Red/E...
Expanding strain coverage of a group A Streptococcus pilus-expressing Lactococcus lactis mucosal vaccine.
Publication Type: Academic Journal
Source(s): Immunology and cell biology [Immunol Cell Biol] 2023 Jul; Vol. 101 (6), pp. 545-555. Date of Electronic Publication: 2023 Apr 24.
Abstract: Group A Streptococcus (GAS) is a human pathogenic bacterium that can trigger a wide range of diseases, including the autoimmune diseases acute rheumatic fever and rheumatic heart disease, causing major morbidity and mortality in many low- and middle-in...
Neuroprotective effects of hydroponic ginseng fermented by Lactococcus lactis KC24 in oxidatively stressed SH-SY5Y cells.
Publication Type: Academic Journal
Source(s): Journal of the science of food and agriculture [J Sci Food Agric] 2023 Jul; Vol. 103 (9), pp. 4413-4420. Date of Electronic Publication: 2023 Mar 09.
Abstract: Background: Panax ginseng Meyer, a traditional herb in Asia, contains bioactive compounds such as polyphenolic compounds, flavonoids, and ginsenosides. Furthermore, fermentation with probiotics can promote the biofunctional activities of ginseng. This ...
Determination of antilisterial effect of some microbial isolates from traditional zlatar cheese during the fermentation of soft white cheese.
Publication Type: Academic Journal
Source(s): Food science and technology international = Ciencia y tecnologia de los alimentos internacional [Food Sci Technol Int] 2023 Jul; Vol. 29 (5), pp. 529-540. Date of Electronic Publication: 2022 Apr 28.
Abstract: The aim of this study was to select autochthonous lactic acid bacteria (LAB) isolates with antilisterial activity from Zlatar cheese and to evaluate the ability of selected LAB to control Listeria monocytogenes growth during soft white cheese productio...
Cloning and Recombinant Protein Expression in Lactococcus lactis.
Publication Type: Academic Journal
Source(s): Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2652, pp. 3-20.
Abstract: The Lactococcus lactis, a Gram-positive bacteria, is an ideal expression host for the overproduction of heterologous proteins in a properly folded and functional form. L. lactis has been identified as an efficient cell factory, generally recognized as ...