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Overall and Event-free Survival in Children with Acute Lymphoblastic Leukemia and Evaluation of Treatment Related Acute Toxicity.
Publication Type: Academic Journal
Source(s): Cam ve Sakura Medical Journal. Aug2022, Vol. 2 Issue 2, p49-58. 10p.
Abstract: Objective: The study aimed to evaluate the acute toxicity, overall survival (OS) and event-free survival (EFS) of children with acute lymphoblastic leukemia (ALL). Material and Methods: This study included retrospective analysis of the medical records ...
An evaluation of participation restrictions and associated factors via the ICF-CY framework in children with acute lymphoblastic leukemia receiving maintenance chemotherapy.
Publication Type: Academic Journal
Source(s): European journal of pediatrics [Eur J Pediatr] 2021 Apr; Vol. 180 (4), pp. 1081-1088. Date of Electronic Publication: 2020 Oct 16.
Abstract: Our aim was to determine impairments in physical functions, activity limitations, and participation restrictions with the International Classification of Functioning, Disability and Health version for Children and Youth (ICF-CY) framework in children w...
The Significance of CD20 Intensity Variance in Pediatric Patients with B-Cell Precursor Acute Lymphoblastic Leukemia.
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine. Feb2023, Vol. 12 Issue 4, p1451. 11p.
Abstract: B-cell precursor acute lyphoblastic leukemia (ALL) is a common pediatric malignancy and patients may have significant benefits from monoclonal antibodies therapy with increased survival rates. Positive CD20 expression is identified in about half of the...
The Landscape of Secondary Genetic Rearrangements in Pediatric Patients with B-Cell Acute Lymphoblastic Leukemia with t(12;21).
Publication Type: Academic Journal
Source(s): Cells (2073-4409). Feb2023, Vol. 12 Issue 3, p357. 21p.
Abstract: The most frequent chromosomal rearrangement in childhood B-cell acute lymphoblastic leukemia (B-ALL) is translocation t(12;21)(p13;q22). It results in the fusion of the ETV6::RUNX1 gene, which is active in the regulation of multiple crucial cellular pa...
Clinicolaboratory Characteristics and Outcome of Pediatric Acute Lymphoblastic Leukemia in a ResourceLimited Setting: A Study from South Egypt.
Publication Type: Academic Journal
Source(s): Research in Oncology. Dec2022, Vol. 18 Issue 2, p61-68. 8p.
Abstract: Background: Remarkable progress has been made in the treatment of pediatric acute lymphoblastic leukemia (ALL), with survival rates reaching > 80% in high-income countries. In Egypt, the outcome of treatment of ALL has been less favorable. Aim: To eval...
Frequent detection of CBFA2T3::GLIS2 fusion and RAM-phenotype in pediatric non-Down syndrome acute megakaryoblastic leukemia: a possible novel relationship with aberrant cytoplasmic CD3 expression.
Publication Type: Academic Journal
Source(s): Leukemia & Lymphoma. Feb2023, Vol. 64 Issue 2, p462-467. 6p.
Abstract: The remaining 14 cases showed negative cCD3 by IHC and/or flow cytometry and 12 cases demonstrated concordant cCD3 expression status between IHC and flow cytometry. None of the AMKL with RAM-phenotype or aberrant cCD3 expression showed co-expression of...
Acute Lymphoblastic Leukemia in Children: Better Transplant Outcomes After Total Body Irradiation-based Conditioning.
Publication Type: Academic Journal
Source(s): In Vivo. Nov/Dec2021, Vol. 35 Issue 6, p3315-3320. 6p.
Abstract: Background/Aim: Comparison of transplant outcomes in long-term follow-up of children after total body irradiation (TBI)- or chemotherapy-based conditioning allogeneic hematopoietic cell transplantation (allo-HCT). Patients and Methods: Patients undergo...
A Gene Signature Comprising Seven Pyroptosis-Related Genes Predicts Prognosis in Pediatric Patients with Acute Myeloid Leukemia.
Publication Type: Academic Journal
Source(s): Acta Haematologica. 2022, Vol. 145 Issue 6, p627-641. 15p.
Abstract: Introduction: The aim of the study was to construct a pyroptosis-related risk score (RS) model for the prognosis of acute myeloid leukemia (AML). Methods: The TARGET (training) and E-MTAB-1216 (validation) datasets were downloaded. Pyroptosis-related g...
A Multicenter Cohort Study on Children Suffering from Acute Lymphoblastic Leukemia: Effects of Obesity on Mortality.
Publication Type: Academic Journal
Source(s): Computational & Mathematical Methods in Medicine. 7/5/2022, p1-9. 9p.
Abstract: Background. Overweight and obesity have been reported in specific patients and disease survivors compared to other types of childhood cancer. This study is aimed at determining the effect of children's obesity on the mortality of acute lymphoblastic le...
Invasive Fungal Infection Caused by Magnusiomyces capitatus in an Immunocompromised Pediatric Patient with Acute Lymphoblastic Leukemia in Mexico City: A Case Report.
Publication Type: Academic Journal
Source(s): Journal of Fungi. Aug2022, Vol. 8 Issue 8, p851-851. 7p.
Abstract: Magnusiomyces capitatus (also denominated "Geotrichum capitatum" and "the teleomorph stage of Saprochaete capitata") mainly affects immunocompromised patients with hematological malignancies in rare cases of invasive fungal infections (IFIs). Few cases...