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Quality of laboratory biomarker monitoring during treatment with lithium in patients with bipolar disorder.
Publication Type: Academic Journal
Source(s): Bipolar disorders [Bipolar Disord] 2023 Sep; Vol. 25 (6), pp. 499-506. Date of Electronic Publication: 2023 Feb 01.
Abstract: Background: Clinical guidelines recommend monitoring of creatinine and lithium throughout treatment with lithium. We here assessed the extent to which this occurs in healthcare in Sweden.Methods: This is an observational study of all adults with bipola...
Practices, knowledge, and attitudes about lithium treatment: Results of online surveys completed by clinicians and lithium-treated patients.
Publication Type: Academic Journal
Source(s): Journal of psychiatric research [J Psychiatr Res] 2023 Aug; Vol. 164, pp. 335-343. Date of Electronic Publication: 2023 Jun 26.
Abstract: Background: Lithium remains the gold-standard medication for acute and prophylactic treatment of bipolar disorder. Understanding clinicians' practices and patients' experiences, knowledge and attitudes about lithium may improve its clinical use.Methods...
Different pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania.
Publication Type: Academic Journal
Source(s): Journal of psychiatric research [J Psychiatr Res] 2023 Aug; Vol. 164, pp. 192-201. Date of Electronic Publication: 2023 Jun 17.
Abstract: Lithium carbonate (LiCO) is a mainstay therapeutic for the prevention of mood-episode recurrences in bipolar disorder (BD). Unfortunately, its narrow therapeutic index is associated with complications that may lead to treatment non-compliance. Intrigui...
Preparation and Performance of Regenerated Al 2 O 3 -Coated Cathode Material LiNi 0.8 Co 0.15 Al 0.05 O 2 from Spent Power Lithium-Ion Batteries.
Publication Type: Academic Journal
Source(s): Molecules (Basel, Switzerland) [Molecules] 2023 Jul 02; Vol. 28 (13). Date of Electronic Publication: 2023 Jul 02.
Abstract: In this study, LiNi 0.8 Co 0.15 Al 0.05 O 2 @x%Al 2 O 3- coated cathode materials were regeneratively compounded by the solid-phase sintering method, and their structural characterization and electrochemical performance were systematically analyzed. Th...
Lithium Therapy in Old Age: Recommendations from a Delphi Survey.
Publication Type: Academic Journal
Source(s): Pharmacopsychiatry [Pharmacopsychiatry] 2023 Sep; Vol. 56 (5), pp. 188-196. Date of Electronic Publication: 2023 Jul 28.
Abstract: Introduction: While lithium (Li) has been well established for the treatment of bipolar disorder, geriatric patients require special attention when it comes to issues of drug safety. Declining renal function, amongst other medical conditions, and polyp...
Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors.
Publication Type: Academic Journal
Source(s): Translational psychiatry [Transl Psychiatry] 2023 Jul 13; Vol. 13 (1), pp. 258. Date of Electronic Publication: 2023 Jul 13.
Abstract: Central nervous system (CNS) tumors account for almost a third of pediatric cancers and are the largest contributor to cancer-related death in children. Cranial radiation therapy (CRT) is, often in combination with chemotherapy and surgery, effective i...
Lithium prevents glucocorticoid‑induced chondrocyte autophagy: An in vitro study.
Publication Type: Academic Journal
Source(s): Molecular medicine reports [Mol Med Rep] 2023 Oct; Vol. 28 (4). Date of Electronic Publication: 2023 Aug 18.
Abstract: Glucocorticoids can induce chondrocyte autophagy. Lithium is a classical regulator of autophagy. The present study aimed to determine whether lithium can prevent glucocorticoid‑induced chondrocyte autophagy by regulating the PI3K/AKT/mTOR signaling pat...
Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways.
Publication Type: Academic Journal
Source(s): Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2023 Jun; Vol. 48 (7), pp. 1000-1010. Date of Electronic Publication: 2022 Nov 14.
Abstract: Bipolar disorder (BD) is a highly heritable mood disorder with intermittent episodes of mania and depression. Lithium is the first-in-line medication to treat BD, but it is only effective in a subset of individuals. Large-scale human genomic studies ha...
Determination of lithium concentration in capillary blood using volumetric dried blood spots.
Publication Type: Academic Journal
Source(s): Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Apr 01; Vol. 227, pp. 115269. Date of Electronic Publication: 2023 Jan 29.
Abstract: Background: Lithium is a cornerstone in the treatment of bipolar disorder and is considered one of the most effective treatments in psychiatry at large. Lithium treatment requires individual dosing with frequent serum concentration measurements due to ...
Lithium use and the risk of chronic kidney disease.
Publication Type: Editorial & Opinion
Source(s): Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2023 Apr; Vol. 132 (4), pp. 295-296. Date of Electronic Publication: 2023 Jan 13.