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Advanced Search Results For "MULTIVARIATE analysis"

1 - 10 of 316,026 results for
 "MULTIVARIATE analysis"
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Quantification strategies for two-dimensional liquid chromatography datasets using regions of interest and multivariate curve resolution approaches.

Publication Type:Academic Journal

Source(s):Talanta [Talanta] 2022 Sep 01; Vol. 247, pp. 123586. Date of Electronic Publication: 2022 May 27.

Abstract:In this work, three chemometrics-based approaches are compared for quantification purposes when using two-dimensional liquid chromatography (LC×LC-MS), taking as a study case the quantification of amino acids in commercial drug mixtures. Although the a...

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Limitations of multivariate survival analysis.

Publication Type:Editorial & Opinion

Source(s):Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2022 Jul; Vol. 35 (7), pp. 993. Date of Electronic Publication: 2021 Aug 07.

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Reply to "Limitations of multivariate survival analysis".

Publication Type:Editorial & Opinion

Source(s):Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2022 Jul; Vol. 35 (7), pp. 994-995. Date of Electronic Publication: 2021 Dec 28.

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A New Alternative Tool to Analyse Glycosylation in Monoclonal Antibodies Based on Drop-Coating Deposition Raman imaging: A Proof of Concept.

Publication Type:Academic Journal

Source(s):Molecules (Basel, Switzerland) [Molecules] 2022 Jul 09; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 09.

Abstract:Glycosylation is considered a critical quality attribute of therapeutic proteins as it affects their stability, bioactivity, and safety. Hence, the development of analytical methods able to characterize the composition and structure of glycoproteins is...

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Detection of low numbers of bacterial cells in a pharmaceutical drug product using Raman spectroscopy and PLS-DA multivariate analysis.

Publication Type:Academic Journal

Source(s):The Analyst [Analyst] 2022 Jul 22; Vol. 147 (15), pp. 3593-3603. Date of Electronic Publication: 2022 Jul 22.

Abstract:Sterility testing is a laborious and slow process to detect contaminants present in drug products. Raman spectroscopy is a promising label-free tool to detect microorganisms and thus gaining relevance as a future alternative culture-free method for ste...

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Determination of aflatoxin B 1 (AFB 1 ) in maize based on a portable Raman spectroscopy system and multivariate analysis.

Publication Type:Academic Journal

Source(s):Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2022 Jul 05; Vol. 275, pp. 121148. Date of Electronic Publication: 2022 Mar 15.

Abstract:Aflatoxin B 1 (AFB 1 ) is the most widely distributed, most toxic, and most harmful, and it is widely present in moldy grains. This study proposes a new method for quantitative and rapid determination of the AFB 1 content in maize based on Raman spectr...

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Using MVDA with stoichiometric balances to optimize amino acid concentrations in chemically defined CHO cell culture medium for improved culture performance.

Publication Type:Academic Journal

Source(s):Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Feb; Vol. 119 (2), pp. 452-469. Date of Electronic Publication: 2021 Dec 04.

Abstract:Chemically defined (CD) media are routinely used in the production of biologics in Chinese hamster ovary (CHO) cell culture and provide enhanced raw material control. Nutrient optimized CD media is an important path to increase cell growth and monoclon...

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Mass spectrometry imaging to explore molecular heterogeneity in cell culture.

Publication Type:Academic Journal

Source(s):Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jul 19; Vol. 119 (29), pp. e2114365119. Date of Electronic Publication: 2022 Jul 11.

Abstract:Molecular analysis on the single-cell level represents a rapidly growing field in the life sciences. While bulk analysis from a pool of cells provides a general molecular profile, it is blind to heterogeneities between individual cells. This heterogene...

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Preparation of AgNPs self-assembled solid-phase substrate via seed-mediated growth for rapid identification of different bacterial spores based on SERS.

Publication Type:Academic Journal

Source(s):Food research international (Ottawa, Ont.) [Food Res Int] 2022 Oct; Vol. 160, pp. 111426. Date of Electronic Publication: 2022 May 27.

Abstract:In this study, we developed a novel and sensitive AgNPs self-assembled solid-phase (AgNPs-SASP) SERS substrate platform using seed-mediated and liquid interface self-assembly methods and applied the platform for the detection of three bacterial spores....

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Physicochemical characteristics, antioxidant properties and bacterial profiling of three Malaysian honey varieties: a study using multivariate analysis.

Publication Type:Academic Journal

Source(s):Journal of the science of food and agriculture [J Sci Food Agric] 2022 Sep; Vol. 102 (12), pp. 5440-5451. Date of Electronic Publication: 2022 Apr 22.

Abstract:Background: The physicochemical characteristics, antioxidant properties, and bacterial profiles of Heterotrigona itama, Apis dorsata, and Apis mellifera honey of Malaysian origin were studied and the results were assessed using Pearson correlation anal...

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