Advanced Search Results For "NATURAL immunity"
Your filters
Significance of the cGAS-STING Pathway in Health and Disease.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 17, p13316. 28p.
Abstract: The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a significant role in health and disease. In this pathway, cGAS, one of the major cytosolic DNA sensors in mammalian cells, regulates innate immunity and the STING-...
Pullulan-Based Active Coating Incorporating Potassium Metabisulfite Maintains Postharvest Quality and Induces Disease Resistance to Soft Rot in Kiwifruit.
Publication Type: Academic Journal
Source(s): Foods. Sep2023, Vol. 12 Issue 17, p3197. 18p.
Abstract: Soft rot is a severe postharvest disease of kiwifruit that causes enormous economic losses annually. In this study, we aimed to explore an effective pullulan-based active coating, incorporating food additives to reduce soft rot and extend the shelf lif...
Role of Innate Immunity in Allergic Contact Dermatitis: An Update.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 16, p12975. 27p.
Abstract: Our understanding of allergic contact dermatitis mechanisms has progressed over the past decade. Innate immune cells that are involved in the pathogenesis of allergic contact dermatitis include Langerhans cells, dermal dendritic cells, macrophages, mas...
Transcriptome Analyses Revealed the Wax and Phenylpropanoid Biosynthesis Pathways Related to Disease Resistance in Rootstock-Grafted Cucumber.
Publication Type: Academic Journal
Source(s): Plants (2223-7747). Aug2023, Vol. 12 Issue 16, p2963. 13p.
Abstract: Cucumbers (Cucumis sativus L.) are a global popular vegetable and are widely planted worldwide. However, cucumbers are susceptible to various infectious diseases such as Fusarium and Verticillium wilt, downy and powdery mildew, and bacterial soft rot, ...
Innate Immune System in the Context of Radiation Therapy for Cancer.
Publication Type: Academic Journal
Source(s): Cancers. Aug2023, Vol. 15 Issue 15, p3972. 22p.
Abstract: Simple Summary: Ionizing radiation therapy is an important component of cancer treatment. This review provides a summary of the latest advancements, clinical use, and limitations of radiation therapy. Moreover, this review explores how radiation affect...
Transcriptomic Maps of Colorectal Liver Metastasis: Machine Learning of Gene Activation Patterns and Epigenetic Trajectories in Support of Precision Medicine.
Publication Type: Academic Journal
Source(s): Cancers. Aug2023, Vol. 15 Issue 15, p3835. 31p.
Abstract: Simple Summary: Liver metastasis is a significant factor contributing to mortality associated with colorectal cancer. Establishing the biological mechanisms of metastasis is crucial for refining diagnostics and identifying therapeutic windows for inter...
Emerging Roles of Cells and Molecules of Innate Immunity in Alzheimer's Disease.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 15, p11922. 22p.
Abstract: The inflammatory response that marks Alzheimer's disease (neuroinflammation) is considered a double-edged sword. Microglia have been shown to play a protective role at the beginning of the disease. Still, persistent harmful stimuli further activate mic...
Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis.
Publication Type: Academic Journal
Source(s): Cells (2073-4409). Jul2023, Vol. 12 Issue 14, p1913. 19p.
Abstract: Joint pain severity in arthritic diseases differs between sexes and is often more pronounced in women. This disparity is thought to stem from biological mechanisms, particularly innate immunity, yet the understanding of sex-specific differences in arth...
ROP16 of Toxoplasma gondii Inhibits Innate Immunity by Triggering cGAS-STING Pathway Inactivity through the Polyubiquitination of STING.
Publication Type: Academic Journal
Source(s): Cells (2073-4409). Jul2023, Vol. 12 Issue 14, p1862. 17p.
Abstract: cGAS-STING signaling is a major pathway in inducing type Ⅰ IFN, which plays a crucial role in the defense against T. gondii infection. In contrast, T. gondii develops multiple strategies to counteract the host defense, causing serious diseases in a wid...
Short Peptides of Innate Immunity Protein Tag7 (PGLYRP1) Selectively Induce Inhibition or Activation of Tumor Cell Death via TNF Receptor.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 14, p11363. 12p.
Abstract: In this study, we have found two peptides of Tag7 (PGLYRP1) protein-17.1A (HRDVQRT) and 17.1B (RSNYVLKG), that have different affinities to the TNFR1 receptor and the Hsp70 protein. Peptide 17.1A is able to inhibit signal transduction through the TNFR1...